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  1. Titanium and its alloys have been widely employed for bone tissue repair and implant manufacturing. The rapid development of three-dimensional (3D) printing technology has allowed fabrication of porous titaniu...

    Authors: Yifei Gu, Yi Sun, Sohaib Shujaat, Annabel Braem, Constantinus Politis and Reinhilde Jacobs
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:68
  2. Patellar dislocations in patients presenting with recurrent patellofemoral instability can damage the surrounding structures, limiting patient’s participation to recreational activities and quality of life. Th...

    Authors: Filippo Migliorini, Emanuela Marsilio, Francesco Oliva, Jörg Eschweiler, Frank Hildebrand and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:63
  3. High tibial osteotomy (HTO) has been used for the treatment of patients with knee osteoarthritis. However, the successful implementation of HTO requires precise intraoperative positioning, which places greater...

    Authors: Zhuang Miao, Songlin Li, Desu Luo, Qunshan Lu and Peilai Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:62
  4. This study assessed the accuracy of robotic-arm-assisted total knee arthroplasty (RATKA) for bone resection, component size prediction, implant placement, and limb alignment.

    Authors: Chenkai Li, Zian Zhang, Guanrong Wang, Chun Rong, Wanping Zhu, Xinzhe Lu, Yikai Liu and Haining Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:61
  5. While the precise measurement of the range of motion (ROM) of the elbow joint is important for clinical assessment and rehabilitation, problems include low accuracy and reproducibility in goniometer measuremen...

    Authors: Kohei Yamaura, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takeshi Kataoka, Takashi Kurosawa, Shintaro Mukohara, Yuichi Hoshino, Takahiro Niikura, Kouki Nagamune and Ryosuke Kuroda
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:60
  6. The empirical use of tranexamic acid (TXA) for bleeding remains controversial because of the distinct fibrinolytic phenotypes observed after injury. This study sought to assess the efficacy of postoperative TX...

    Authors: Jiacheng Liu, Han Wang, Xiangdong Wu, Yiting Lei and Wei Huang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:59
  7. Surgical management of adolescent idiopathic scoliosis (AIS) can be performed using standard posterior spinal fusion (PSF) or with a posterior minimally invasive approach. Minimally invasive scoliosis surgery ...

    Authors: Honghao Yang, Xiangyuan Jia and Yong Hai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:58
  8. This study retrospectively analyzed and evaluated the potential correlations of serum calcium, serum phosphorus, and calcium-phosphorus product (Ca–P product) with the incidence of osteoporotic vertebral compr...

    Authors: Pu Ying, Mingjia Gu, Xiaowei Jiang, Yue Xu, Lu Tong, Yi Xue, Qiang Wang, Zhihui Huang, Wenge Ding and Xiaoyu Dai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:57
  9. Elderly acetabular fractures are one of the more difficult types of fractures to resolve. For patients at this age, the more common type of fracture is comminuted. How to better fix this type of fracture has a...

    Authors: Guixiong Huang, Kaifang Chen, Yulong Wang and Xiaodong Guo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:56
  10. We evaluated the radiologic and clinical outcomes of a lateral incision single plate with and a single-incision double plating in elderly patients with osteoporotic distal femoral fractures.

    Authors: Dae Jin Nam, Min Seok Kim, Tae Ho Kim, Min Woo Kim and Suc Hyun Kweon
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:55
  11. Circular RNAs (circRNAs) have emerged as vital regulators in the development of rheumatoid arthritis (RA). In this study, we aimed to explore the functions and mechanisms of circ_0001947 in RA.

    Authors: Yang Yang, Shudian Lin, Zhou Yang, Yanyan Huang and Feng Zhan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:54
  12. Osteoclast cell increase is a major risk factor for osteoporosis and degenerative bone and joint diseases. At present, RANKL and M-CSF are commonly used to induce osteoclastogenesis. Thioacetamide (TAA) can le...

    Authors: XiaoLi Jin, Yang Li, Yayang Yang, Hao Shen, Jin Chen, Bin Xu and Jian Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:53
  13. Although the use of intraoperative computed tomography (CT)-based navigation systems is unlikely to cause intraoperative contamination more than the use of intraoperative fluoroscopy, the association between i...

    Authors: Gentaro Kumagai, Kanichiro Wada, Sunao Tanaka, Toru Asari, Yohshiro Nitobe and Yasuyuki Ishibashi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:52
  14. The treatment of comminuted posterior wall acetabular fractures remains challenging due to the difficulty in understanding of fracture patterns and lack of appropriate preoperative planning process. Virtual pr...

    Authors: Yifan Zheng, Jianan Chen, Siyu Yang, Xi Ke, Dan Xu, Guodong Wang, Xianhua Cai and Ximing Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:51
  15. To identify medial open-wedge high tibial osteotomy (MOWHTO) prognostic factors with wedge-shaped spacer implantation (spacer-type MOWHTO) for varus medial compartment knee osteoarthritis.

    Authors: Fengkun Wang, Wenru Ma, Jinli Chen, Wenbin Cong, Yingze Zhang, Tengbo Yu and Yi Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:50
  16. Adipose-derived mesenchymal stem cells (ADSCs), as seed cells for tendon tissue engineering, are promising for tendon repair and regeneration. But for ADSCs, diverse oxygen tensions have different stimulatory ...

    Authors: Xing Guo, Denghua Huang, Dan Li, Longfei Zou, Hui Lv, Yuanhui Wang and Meiyun Tan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:49
  17. Knee osteoarthritis (KOA) is based on degenerative pathological changes. miR-155 is involved in regulating KOA. This study estimated the mechanism of miR-155 in mouse KOA chondrocytes.

    Authors: Gen Li, Lijun Xiu, Xiaoyun Li, Lisha Ma and Jihui Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:48
  18. The clinical outcomes of using a zero-profile for anterior cervical decompression and fusion were evaluated by comparison with anterior cervical plates.

    Authors: Tingxin Zhang, Nana Guo, Gang Gao, Hao Liu, Yanhong Li, Feng Gao, Qingxin Zhang, Xiaoyang Tao, Wupeng Yang and Yongjiang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:47
  19. This study aimed to evaluate the short-term effect of radial shockwave on the median nerve pathway as a new model method in patients with mild-to-moderate carpal tunnel syndrome.

    Authors: Atieh Habibzadeh, Roghayeh Mousavi-Khatir, Payam Saadat and Yahya Javadian
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:46
  20. Fifth metatarsal base fracture (fifth MBF) and lateral collateral ankle ligament (LCAL) injury are mainly caused by plantar flexion and inversion of the foot. However, there is no relevant report on the incide...

    Authors: Hongbin Cao, Nan Li, Guixin Wang and Jinquan He
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:45
  21. Surgical treatment is advised for unstable distal clavicle fractures (UDCFs). Various kinds of internal fixation methods have been used, but the best fixation is still controversial.

    Authors: Yinglong Xu, Xiaobo Guo, Hui Peng, Hai Dai, Zonggui Huang and Jinmin Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:43
  22. Image-guided joint aspirations used to assist the diagnosis of periprosthetic joint infection (PJI) may commonly result in a dry tap–or insufficient fluid for culture and cell count analysis. Dry tap aspiratio...

    Authors: Justin Ong, Alex Tang, Joshua C. Rozell, James S. Babb, Ran Schwarzkopf and Dana Lin
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:42
  23. The purpose of this study was to investigate the incidence of deep vein thrombosis (DVT) and clarify the risk factors of DVT in patients with femoral neck fracture.

    Authors: Chenhao Dou, Tianhua Li, Shuhong Yang, Qian Geng, Qing Lu, Yahui Zhang, Jingjing Yu, Fang Hu and Junqin Ding
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:41
  24. Recently facet joint block has been increasingly used to relief the residual pain after vertebral augmentation, but whether it can be a complementary or alternative to vertebral augmentation remain largely unk...

    Authors: Zhi Chen, Chenyang Song, Jianwen Chen, Jun Sun and Wenge Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:40
  25. Calcaneal fractures are associated with numerous complications and a poor prognosis with significant long-term quality-of-life issues, regardless of treatment. Therefore, in-depth research into the underlying ...

    Authors: Qingwen Yu, Zhirui Li, Jiantao Li, Qinghua Yu, Licheng Zhang, Daohong Liu, Mingzhu Zhang and Peifu Tang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:39
  26. Ankle sprain is the most common lower limb injury in physically active individuals. Loss of function, decreased postural control (PC), strength deficit, and reduced range of motion (ROM) are common after acute...

    Authors: Antonio Manoel Goulart Neto, Nicola Maffulli, Filippo Migliorini, Fábio Sprada de Menezes and Rodrigo Okubo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:38
  27. Osteosarcoma (OS) is one of the most common malignant bone tumors in children and adolescents. Circular RNAs (circRNAs) are critical regulators involved in multiple physiological and pathological processes. Ho...

    Authors: Ziyan Zhang, Lin Zhou, Shicheng Zhou and Xin Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:37
  28. Recently, the management of musculoskeletal disorders with the patients' own stem cells, isolated from the walls of small blood vessels, which can be found in great numbers in the adipose tissue, has received ...

    Authors: John P. Furia, Mark A. Lundeen, Jason L. Hurd, David A. Pearce, Christopher Alt, Eckhard U. Alt, Christoph Schmitz and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:36
  29. The treatment of complex 3- and 4-part proximal humeral fractures has been controversial due to numerous postoperative complications. With the further study of medial support and blood supply of humeral head, ...

    Authors: Hao Xiang, Yan Wang, Yongliang Yang, Fanxiao Liu, Qingsen Lu, Lingpeng Kong, Mingzhen Li, Yong Han and Fu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:35
  30. Fluorescence-guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) and other contrast agents has shown its efficacy in improving resection margins, local recurrence and survival rates in several medical disc...

    Authors: Wiebke K. Guder, Wolfgang Hartmann, Clarissa Buhles, Maike Burdack, Maike Busch, Nicole Dünker, Jendrik Hardes, Uta Dirksen, Sebastian Bauer and Arne Streitbürger
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:34
  31. Talar cartilage injury is a kind of disease that causes long-term and chronic pain of ankle joint. Autologous osteochondral transplantation has been viewed as an alternative choice for treating these lesions, ...

    Authors: Xin Wang, Dong Zhang, Fengqi Zhang, Lin Jin, Donglin Shi and Zhiyong Hou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:33
  32. The subcutaneous screw rod system, commonly known as the internal pelvic fixator (INFIX), is useful in managing unstable pelvic ring fractures. Conventional INFIX and transiliac–transsacral (TITS) screw techni...

    Authors: Akihiko Hiyama, Taku Ukai, Satoshi Nomura and Masahiko Watanabe
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:32
  33. To determine the incidence of concomitant intra-articular glenohumeral injuries in patients undergoing surgical management from distal clavicle fractures (DCF) with shoulder arthroscopy and their impact on out...

    Authors: Theodorakys Marín Fermín, Filippo Migliorini, Emmanuel Papakostas, Khalid Al-Khelaifi, David Ricardo Maldonado, Jean Michel Hovsepian and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:31
  34. Unilateral biportal endoscopic discectomy (UBE) is a rapidly growing surgical method that uses arthroscopic system for treatment of lumbar disc herniation (LDH), while percutaneous endoscopic lumbar discectomy...

    Authors: Hao-Wei Jiang, Cheng-Dong Chen, Bi-Shui Zhan, Yong-Li Wang, Pan Tang and Xue-Sheng Jiang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:30
  35. Induced membrane (IM) is the key component of Masquelet reconstruction surgery for the treatment of bone defects. IM is formed around the cement spacer and is known to secrete growth factors and osteoinductive...

    Authors: Takahiro Niikura, Takahiro Oda, Naoe Jimbo, Masato Komatsu, Keisuke Oe, Tomoaki Fukui, Tomoyuki Matsumoto, Shinya Hayashi, Takehiko Matsushita, Tomoo Itoh and Ryosuke Kuroda
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:29
  36. Rotator cuff tears are one of the most common shoulder injuries in the older population. This study aimed to determine whether acromioplasty reliably decreases the critical shoulder angle (CSA) and describe an...

    Authors: Mingtao Zhang, Zhitao Yang, Borong Zhang, Tao Liu, Jin Jiang and Xiangdong Yun
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:28
  37. Anteromedial cortical support apposition (positive and/or neutral cortical relations) is crucial for surgical stability reconstruction in the treatment of trochanteric femur fractures. However, the loss of fra...

    Authors: Hui Song, Shi-Min Chang, Sun-Jun Hu and Shou-Chao Du
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:27
  38. Although ACDF has been widely used in treating cervical spondylosis and related diseases, the complications along with this anterior surgical technique have hindered its application and affected the postoperat...

    Authors: Leixin Wei, Chen Xu, Minjie Dong, Yibo Dou, Ye Tian, Huiqiao Wu, Xiaodong Wu, Xinwei Wang, Huajiang Chen, Xiaolong Shen, Peng Cao and Wen Yuan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:26
  39. This study aimed to assess whether use of continuous passive motion (CPM) could improve range of motion in patients after total knee arthroplasty (TKA), if it could affect the surgical wound aspect (SWA) and i...

    Authors: Sergi Gil-González, Ricardo Andrés Barja-Rodríguez, Antoni López-Pujol, Hussein Berjaoui, Jose Enrique Fernández-Bengoa, Juan Ignacio Erquicia, Joan Leal-Blanquet and Xavier Pelfort
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:25
  40. The shoulder joint is the most commonly injured joint in CrossFit practitioners, because of the high intensity and loads associated with this sport. Despite the large number of clinical cases, there is a short...

    Authors: Elisa Raulino Silva, Nicola Maffulli, Filippo Migliorini, Gilmar Moraes Santos, Fábio Sprada de Menezes and Rodrigo Okubo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:24
  41. The treatment of anterior shoulder instability is a focus in the field of sports medicine. While much research has been conducted, few bibliometric studies have been performed in this field. This study analyze...

    Authors: Mingtao Zhang, Zhitao Yang, Borong Zhang, Tao Liu and Xiangdong Yun
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:23
  42. Morton's neuroma (MN) is a common cause of forefoot pain. After failure of conservative management, surgical procedures include neurectomy or neuroma preserving procedures; resection of deep transverse interme...

    Authors: Manjunath Koti, Nicola Maffulli, Muwaffak Al-Shoaibi, Michael Hughes and Jack McAllister
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:22
  43. The clinical utility of radiofrequency (RF) in patients with knee osteoarthritis (OA) remains unclear. We conducted a meta-analysis to systematically evaluate the efficacy and safety of RF treatment in patient...

    Authors: Jian Liu, Ting Wang and Zhen-Hua Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:21
  44. The lung injury is often secondary to severe trauma. In the model of crush syndrome, there may be secondary lung injury. We hypothesize that high-mobility group box 1 (HMGB1), released from muscle tissue, medi...

    Authors: Bin-Fei Zhang, Wei Song, Jun Wang, Peng-Fei Wen and Yu-Min Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:20
  45. To explore the relationship between the strength of posterior cervical extensors (PCEs) and cervical sagittal alignment in Hirayama disease (HD) patients.

    Authors: Ye Tian, Lin Xie, Jianyuan Jiang and Hongli Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:19
  46. The efficacy of tourniquet use during primary total knee arthroplasty (TKA) is thought to reduce intraoperative blood loss, improve surgical exposure, and optimize cement fixation. Tranexamic acid (TXA) use ca...

    Authors: Changjiao Sun, Xiaofei Zhang, Qi Ma, Yan Tu, Xu Cai and Yonggang Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:18
  47. To compare the anterior translation and internal rotation of tibia on magnetic resonance imaging (MRI) between adult and adolescent patients with anterior cruciate ligament (ACL) tears.

    Authors: Chih-Kai Hong, Yu-Ju Lin, Ting-An Cheng, Chih-Hsun Chang, Kai-Lan Hsu, Fa-Chuan Kuan and Wei-Ren Su
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:17
  48. Good clinical outcomes for locking plates as an external fixator to treat tibial fractures have been reported. However, external locking plate fixation is still generally rarely performed. This study aimed to ...

    Authors: Dejan Blažević, Janoš Kodvanj, Petra Adamović, Dinko Vidović, Zlatko Trobonjača and Srećko Sabalić
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:16
  49. This study aims to investigate the incidence, occurrence timing and locations of preoperative DVT and identify the associated factors in this group.

    Authors: Kai Ding, Haicheng Wang, Yuxuan Jia, Yan Zhao, Weijie Yang, Wei Chen and Yanbin Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:15

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