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  1. Hip replacement is divided into total hip arthroplasty (THA) and hemiarthroplasty (HA); it is still controversial whether to choose THA or HA for femoral neck fractures (FNF). The goal of this study was to rev...

    Authors: Xinbo Li and Jianning Luo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:172

    Content type: Systematic review

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  2. When multicystic vesicles (precursors of exosomes) are formed in cells, there are two results. One is decomposition by lysosomes, and the other is the generation of exosomes that are transported out through th...

    Authors: Wenbo Zhao, Junxian Hu and Qingyi He

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:171

    Content type: Research article

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  3. The dysregulation of circular RNAs (circRNAs) has been identified in various human diseases, including osteoarthritis (OA). The purpose of this study was to identify the role and mechanism of circ_SLC39A8 in r...

    Authors: Jizhe Yu, Yushuang Qin and Naxin Zhou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:170

    Content type: Research article

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  4. The purpose of this prospective study was to introduce the application of a double reverse traction repositor (DRTR) in the retrograde intramedullary nailing (RE-IMN) of AO/OTA 33A distal femur fractures.

    Authors: Xiaodong Lian, Kuo Zhao, Wei Chen, Junzhe Zhang, Junyong Li, Hongyu Meng, Zhiyong Hou and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:168

    Content type: Research article

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  5. Lumbar interbody fusion is a standard technique for treating degenerative lumbar disorders involving instability. Due to its invasiveness, a minimally invasive technique, extraforaminal lumbar interbody fusion...

    Authors: Motohide Shibayama, Guang Hua Li, Li Guo Zhu, Zenya Ito and Fujio Ito

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:166

    Content type: Research article

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  6. Circular RNAs (circRNAs) are associated with rheumatoid arthritis (RA) development. The purpose of this study is to explore the function and mechanism of circRNA fragile mental retardation 2 (circ-AFF2) in the...

    Authors: Wei Qu, Ling Jiang and Guanhua Hou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:165

    Content type: Research article

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  7. Wide-awake local anesthesia no tourniquet (WALANT) technique has emerged among hand surgeons with other indications. Surgeries involving pedicled flap and revascularization are no longer used as contraindicati...

    Authors: Jianhua Xu, Lu Yin, Shuming Cao, Haihua Zhan, Jianbing Zhang, Qiang Zhou and Ketong Gong

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:164

    Content type: Research article

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  8. Heterotopic ossifications are a common complication after total hip arthroplasty. Low-dose radiation therapy and non-steroidal anti-inflammatory drugs have proven to effectively reduce the rate of heterotopic ...

    Authors: Stella Oberberg, Jan Nottenkämper, Matthias Heukamp, Jan Krapp and Roland E. Willburger

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:163

    Content type: Research article

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  9. Fast track surgery (FTS) has been gradually applied in perioperative management of orthopedic surgery, but there still some research suspected that the prognosis of patients is not as expected and the cost is ...

    Authors: Mingyang Jiang, Siyi Liu, Huachu Deng, Xuzhi Liang and Zhandong Bo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:162

    Content type: Systematic review

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  10. COVID-19 was declared a global emergency in the first quarter of 2020. It is has resulted in and continues in over a million deaths worldwide and halted medical systems and particularly elective surgeries worl...

    Authors: Maciej J. K. Simon and William D. Regan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:161

    Content type: Research article

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  11. This study was designed to observe the expression of important hedgehog (Hh) signal factors in the bone tissue of rats with chronic fluorosis and cultured osteoblasts in order to investigate the role and signi...

    Authors: Chaonan Deng, Lin Xu, Ying Zhang, Lina Zhao, Yan Linghu and Yanni Yu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:160

    Content type: Research article

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  12. Computer-assisted three-dimensional (3D) planning is increasingly delegated to biomedical engineers. So far, the described fracture reduction approaches rely strongly on the performance of the users. The goal ...

    Authors: Christoph Zindel, Philipp Fürnstahl, Armando Hoch, Tobias Götschi, Andreas Schweizer, Ladislav Nagy and Simon Roner

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:159

    Content type: Research article

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  13. Adult developmental dysplasia of the hip is an untreated congenital hip dysplasia that results in adult hip pain. One of the usual and effective methods for the treatment of this condition is periacetabular os...

    Authors: Rui Luo, Guomin Li, Bo Li, Ruyin Hu and Yankun Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:157

    Content type: Research article

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  14. Accurate preoperative planning is an important step for accurate reconstruction in total hip arthroplasty (THA). Presently, preoperative planning is completed using either a two-dimensional (2D) template or th...

    Authors: Jiabang Huo, Guangxin Huang, Dong Han, Xinjie Wang, Yufan Bu, Ya Chen, Daozhang Cai and Chang Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:156

    Content type: Research article

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  15. On the 11th March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Multiple new guidelines were proposed and existing models of social, domestic and hospital care altered. Most he...

    Authors: Alice Wignall, Vasileios Giannoudis, Chiranjit De, Andrea Jimenez, Simon Sturdee, Sohail Nisar, Hemant Pandit, Aashish Gulati and Jeya Palan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:155

    Content type: Research article

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  16. The coronavirus disease 2019 (COVID-19) pandemic has led to dramatic disruptions to orthopedic services. The purpose of this study is to quantify the reinstatement of elective orthopedic surgeries of our insti...

    Authors: Teng-fei Lou, Zun Ren, Zheng-hua Sun, Wei Wang and Cun-yi Fan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:154

    Content type: Research article

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  17. This study aims to analyze the clinical outcome of a new ultrasound-guided surgery for partial plantar fasciotomy performed with a needle for treatment of plantar fasciitis.

    Authors: A. Iborra, M. Villanueva, P. Sanz-Ruiz, Antonio Martin and Concepción Noriega

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:153

    Content type: Research article

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  18. Elderly patients with femoral neck fractures are at a higher risk of dislocation after hip arthroplasty procedures. In comparison with total hip arthroplasty (THA), bipolar hemiarthroplasty (HA) and dual-mobil...

    Authors: Hsuan-Hsiao Ma, Te-Feng Arthur Chou, Fu-Yuan Pai, Shang-Wen Tsai, Cheng-Fong Chen, Po-Kuei Wu and Wei-Ming Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:152

    Content type: Research article

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  19. Spina bifida occulta (SBO) is one of the most common congenital spinal deformities. Although many studies have demonstrated the influence of lumbosacral dysplasia on low back pain (LBP) in young athletes, ther...

    Authors: Wenhao Li, Zhencheng Xiong, Chunke Dong, Jipeng Song, Liubo Zhang, Jun Zhou, Yanlei Wang, Ping Yi, Feng Yang, Xiangsheng Tang and Mingsheng Tan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:151

    Content type: Research article

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  20. We aimed to investigate the therapeutic effects of Moringa oleifera leaf extracts on osteogenic induction of rat bone marrow mesenchymal stem cells (BMSCs) following peroxidative damage and to explore the underly...

    Authors: Meiling Liu, Haifeng Ding, Hongzhi Wang, Manfeng Wang, Xiaowei Wu, Lu Gan, Luyang Cheng and Xianglu Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:150

    Content type: Research article

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  21. Knee osteoarthritis associated with extra-articular deformity (EAD) can confront the arthroplasty surgeons with challenges of bone resection and soft tissue balancing. The aim of this study was to describe a s...

    Authors: Jing-yang Sun, Guo-qiang Zhang, Jun-min Shen, Yin-qiao Du, Tie-jian Li, Zong-jie Geng, Yong-gang Zhou and Yan Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:149

    Content type: Research article

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  22. Popliteomeniscal fascicles (PMF) are considered the posterolateral meniscocapsular extensions which connect the lateral meniscus to the edge of the tibia. PMFs disruption leads to hypermobility of the lateral ...

    Authors: Alessio D’Addona, Andrea Izzo, Giovanni Di Vico, Donato Rosa and Nicola Maffulli

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:148

    Content type: Systematic review

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  23. Silymarin (SMN), a polyphenolic flavonoid, is involved in multiple bioactive functions including anti-inflammation. Pretreatment with SMN demonstrated chondroprotection against tumour necrosis factor-alpha (TN...

    Authors: Wen-Tien Wu, Yi-Ru Chen, Dai-Hua Lu, Fedor Svyatoslavovich Senatov, Kai-Chiang Yang and Chen-Chie Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:147

    Content type: Research article

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  24. A great deal of evidence has supported that growth differentiation factor 5 (GDF5) is associated with the occurrence of knee osteoarthritis (KOA), while their results are not consistent. In the present study, ...

    Authors: Bin Jia, Yaping Jiang, Yingxing Xu, Yingzhen Wang and Tao Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:146

    Content type: Systematic review

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  25. Muscle strength around the hip after total hip arthroplasty (THA) is crucial for preventing dislocation and limping. This study aimed to assess and compare muscle volume and degeneration after THA using the po...

    Authors: Taku Ukai, Goro Ebihara, Haruka Omura and Masahiko Watanabe

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:145

    Content type: Research article

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  26. The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL...

    Authors: Hai Wang, Leilei Qin, Jiawei Wang and Wei Huang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:144

    Content type: Research article

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  27. Osteoarthritis (OA) is the most common joint disorder in the USA, and knee OA has the highest prevalence. Inflammation and decrease in vascularization are key factors in the degeneration of articular cartilage...

    Authors: Ashim Gupta, Nicola Maffulli, Hugo C. Rodriguez, Cassidy E. Lee, Howard J. Levy and Saadiq F. El-Amin III

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:143

    Content type: Study protocol

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  28. Leg length inequalities (LLI) are a common condition that can be associated with detrimental effects like low back pain and osteoarthritis. Inertial measurement units (IMUs) offer the chance to analyze daily a...

    Authors: Hannah Lena Siebers, Jörg Eschweiler, Valentin M. Quack, Markus Tingart and Marcel Betsch

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:142

    Content type: Research article

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  29. Half of osteonecrosis of the femoral head (ONFH) patients suffer femoral head collapse at initial diagnosis, and more than half are bilaterally affected. This study developed a percutaneous autologous impactio...

    Authors: Yutaka Kuroda, Manabu Nankaku, Yaichiro Okuzu, Toshiyuki Kawai, Koji Goto and Shuichi Matsuda

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:141

    Content type: Research article

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  30. To clarify contemporary indications for first-time revision surgery after primary cementless total hip arthroplasty (THA) for addressing potential issues with cementless THA.

    Authors: Goro Motomura, Satoshi Hamai, Satoshi Ikemura, Masanori Fujii, Shinya Kawahara, Soichiro Yoshino and Yasuharu Nakashima

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:140

    Content type: Research article

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  31. To investigate osteointegration at the graft-bone interface and the prevention of osteoarthritis after anterior cruciate ligament (ACL) reconstruction using a silk-collagen scaffold with both ends modified by ...

    Authors: Fanggang Bi, Yangdi Chen, Junqi Liu, Yafei Wang, Danfeng Xu and Ke Tian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:139

    Content type: Research article

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  32. Biomechanical comparison of wedge and biconcave deformity of different height restoration after augmentation of osteoporotic vertebral compression fractures was analyzed by three-dimensional finite element ana...

    Authors: Xiao-Hua Zuo, Yin-Bing Chen, Peng Xie, Wen-Dong Zhang, Xiang-Yun Xue, Qian-Xi Zhang, Ben Shan, Xiao-Bing Zhang, Hong-Guang Bao and Yan-Na Si

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:138

    Content type: Research article

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  33. Periprosthetic infection is a major cause of failure after segmental endoprosthetic reconstruction. The purpose of this study is to determine whether certain aspects of drain output affect infection risk, part...

    Authors: Jiayong Liu, Zhengfu Fan, Marc El Beaino, Valerae O. Lewis, Bryan S. Moon, Robert L. Satcher, Justin E. Bird, Spencer J. Frink and Patrick P. Lin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:137

    Content type: Research article

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  34. The Wnt planar cell polarity (PCP) pathway is implicated in osteoarthritis (OA) both in animals and in humans. Van Gogh-like 2 (Vangl2) is a key PCP protein that is required for the orientation and alignment o...

    Authors: Ke Zhang, Zhuoying Li, Yunyang Lu, Linyi Xiang, Jiadong Sun and Hong Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:136

    Content type: Research article

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  35. To evaluates the efficacy and safety of rivaroxaban versus aspirin in prevention of venous thromboembolism (VTE) following total hip (THA) or knee arthroplasty (TKA) or hip fracture surgery.

    Authors: Bangsheng Hu, Lianxiang Jiang, Haixia Tang, Meizhu Hu, Jun Yu and Zeping Dai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:135

    Content type: Systematic review

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  36. The aim of this study is to investigate the prognostic value of tibial component coverage (over-hang and under-hang) and the alignment of total knee arthroplasty (TKA) components 1 week after surgery. We selec...

    Authors: Changquan Liu, Guanglei Zhao, Kangming Chen, Jinyang Lyu, Jie Chen, Jingsheng Shi, Gangyong Huang, Feiyan Chen, Yibing Wei, Siqun Wang and Jun Xia

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:134

    Content type: Research article

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  37. Osteoarthritis (OA) is thought to be the most prevalent chronic joint disease, especially in Tibet of China. Here, we aimed to explore the integrative lncRNA and mRNA landscape between the OA patients of Tibet...

    Authors: Junming Luo, Xiaoqin Luo, Zhili Duan, Wenbin Bai, Xiaoming Che, Zhongshu Shan, Xiaona Li and Jinwu Peng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:133

    Content type: Research article

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  38. Osteoarthritis (OA) is a kind of systemic musculoskeletal disorder and a most important factor for causing disability and physical painfulness. Nevertheless, due to the fact that OA can be triggered by multipl...

    Authors: Chao Li, Li Li and Tian Lan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:132

    Content type: Research article

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  39. Three-dimensional preoperative planning was applied for the osteosynthesis of distal radius fractures. The objective of this study was to evaluate the reproducibility of three-dimensional preoperative planning...

    Authors: Yuichi Yoshii, Takeshi Ogawa, Atsuo Shigi, Kunihiro Oka, Tsuyoshi Murase and Tomoo Ishii

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:131

    Content type: Research article

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  40. Although integrated traditional Chinese medicine (TCM) has long been indicated to be effective in the treatment of sciatica and is widely used in the management of this condition, the mechanism by which integr...

    Authors: Yi Wang, Guogang Dai, Yan Xu, Ling Jiang, Zhibin Fu, Jiao Xia, Guogang Tian and Wanli Du

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:130

    Content type: Research article

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  41. Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate...

    Authors: Minghui Sun, Weijun Wang, Lingtian Min, Cheng Chen, Qing Li and Wenjie Weng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:129

    Content type: Research article

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  42. Whether vastus medialis obliquus atrophy exists in patients with patellofemoral pain syndrome and whether the amount of atrophy differs between the vastus medialis obliquus and vastus lateralis muscles remain ...

    Authors: Conglei Dong, Ming Li, Kuo Hao, Chao Zhao, Kang Piao, Wei Lin, Chongyi Fan, Yingzhen Niu and Wang Fei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:128

    Content type: Research article

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  43. With the fourth largest metropolitan population density, motor vehicle drivers in Adelaide, South Australia, record the most number of motor vehicle insurance claims in Australia. Previous studies have shown a...

    Authors: John M. Abrahams, Christopher Sagar and Mark Rickman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:127

    Content type: Research article

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  44. This study was conducted with the aim to compare the effect of posterior condyle offset (PCO) changes on knee joint function of patients following total knee replacement (TKR).

    Authors: Yimin Zhang, Jun Wang, Miao Zhang and Yun Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:126

    Content type: Research article

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  45. Recently, a standardized uptake value (SUV) has been used to evaluate bone single-photon emission computed tomography (SPECT). The aim of this study was to investigate quantitative SPECT imaging of uninfected ...

    Authors: Keisuke Oe, Feibi Zeng, Tomoaki Fukui, Munenobu Nogami, Takamichi Murakami, Tomoyuki Matsumoto, Ryosuke Kuroda and Takahiro Niikura

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:125

    Content type: Research article

    Published on:

  46. Osteoarthritis (OA) is a multiple factorial disease with unidentified specific markers. The alternate method such as biochemical and genetic markers for the diagnosis of osteoarthritis is an undeniable need of...

    Authors: Yasmin Badshah, Maria Shabbir, Hunza Hayat, Zoha Fatima, Asad Burki, Sidra Khan and Shafiq ur Rehman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:124

    Content type: Research article

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  47. This study was performed to investigate the change in the bony alignment of the foot after tendo-Achilles lengthening (TAL) and the factors that affect these changes in patients with planovalgus foot deformity.

    Authors: Nak Tscheol Kim, Young Tae Lee, Moon Seok Park, Kyoung Min Lee, Oh Sang Kwon and Ki Hyuk Sung

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:118

    Content type: Research article

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