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  1. The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these...

    Authors: Xing-jin Wang, Hao Liu, Jun-bo He, Quan Gong, Ying Hong, Xin Rong, Chen Ding, Bei-yu Wang, Yi Yang and Yang Meng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:518

    Content type: Research article

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  2. Direct anterior approach (DAA) has several advantages including shorter length of hospital stay, faster recovery, and better functional outcome while this approach may cause damage to the lateral femoral cutan...

    Authors: Ong-art Phruetthiphat, Vasin Sangthumprateep, Songpol Trakulngernthai, Noppadol Aegakkatajit, Thanainit Chotanaphuti and Malee Chanpoo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:513

    Content type: Research article

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  3. Developmental dysplasia of the hip (DDH) is a highly prevalent hip disease among children. However, its pathogenesis remains unclear. MicroRNAs (miRNA) are important regulators of cartilage development. In a p...

    Authors: Rui Ding, Xijuan Liu, Jian Zhang, Jinghong Yuan, Sikuan Zheng, Xigao Cheng and Jingyu Jia

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:512

    Content type: Research article

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  4. Cannulated screws (CS) are one of the most widely used treatments for femoral neck fracture, however, associated with high rate of complications. In this study, we designed a new type of cannulated screws call...

    Authors: Kai Ding, Weijie Yang, Jian Zhu, Xiaodong Cheng, Haicheng Wang, Du Hao, Song Yinuo, Yanbin Zhu, Yingze Zhang, Wei Chen and Qi Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:511

    Content type: Research article

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  5. The occurrence of chemoresistance is a common problem in tumor treatment. Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance. However, the role and the underlying molecular mechan...

    Authors: Yumei Bai, Yanghua Li, Juan Bai and Yumei Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:510

    Content type: Research article

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  6. Pertrochanteric fractures of the femur in the elderly are very common. As the average age of the population increases, the incidence of such fractures also raises, resulting in high healthcare costs. The type ...

    Authors: Giuseppe Gargano, Nicola Poeta, Francesco Oliva, Filippo Migliorini and Nicola Maffulli

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:509

    Content type: Research article

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  7. Improved oncological and surgical measures now enable curative treatment of malignant lower extremity tumors in majority of cases. Complication rates associated with surgical resection of lower extremity tumor...

    Authors: Moritz von Salis-Soglio, Mohamed Ghanem, Christian Lycke, Andreas Roth and Georg Osterhoff

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:508

    Content type: Research article

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  8. The anterior cruciate ligament (ACL) has a key role as a dynamic stabilizer of the knee joints, and ACL dysfunction caused by traumatic or degenerative rupture accelerates osteoarthritis progression. Thus, it ...

    Authors: Masaru Idota, Shinya Ishizuka, Hideki Hiraiwa, Satoshi Yamashita, Hiroki Oba, Yusuke Kawamura, Takefumi Sakaguchi, Takahiro Haga, Takafumi Mizuno, Itaru Kawashima, Kanae Kuriyama and Shiro Imagama

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:507

    Content type: Research article

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  9. Open reduction internal fixation (ORIF) has long been the conventional procedure for managing displaced patella fracture. This surgical approach has certain drawbacks, which might affect clinical outcomes and ...

    Authors: Chun-Hong Lo and Chih-Hwa Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:506

    Content type: Systematic review

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  10. The femoral neck system (FNS) may be a valid alternative for treating femoral neck fractures, but few studies have compared the outcomes between FNS and cannulated cancellous screws. This study aimed to compar...

    Authors: Yunfeng Tang, Zhen Zhang, Limin Wang, Wei Xiong, Qian Fang and Guanglin Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:504

    Content type: Research article

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  11. Dimensional measurements have been implemented on a variety of entities in morphological studies of the sub-axial cervical vertebral endplate. Despite great progress, little information between the mid-sagitta...

    Authors: Long Wang, Hao T. Luo, Wei Lu, Xing Bo Cai, Chen Yu and Sheng Lu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:503

    Content type: Research article

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  12. Acute compartment syndrome (ACS) is an underestimated complication following tibial plateau fractures. Understanding predictors of ACS in the lower leg after a fracture of the tibial plateau may guide earlier ...

    Authors: Xiangtian Deng, Hongzhi Hu, Zhipeng Ye, Jian Zhu, Yiran Zhang and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:502

    Content type: Research article

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  13. The important functional role the rotator cuff (RC) and biceps play in the shoulder, the close anatomical relationship between them and the high incidence of injuries require an appropriate multidisciplinary t...

    Authors: Rocio Aldon-Villegas, Veronica Perez-Cabezas and Gema Chamorro-Moriana

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:501

    Content type: Systematic review

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  14. Heterotopic ossification (HO) represents pathological lesions that refer to the development of heterotopic bone in extraskeletal tissues around joints. This study investigates the genetic characteristics of bo...

    Authors: Zhanyu Yang, Delong Liu, Rui Guan, Xin Li, Yiwei Wang and Bin Sheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:499

    Content type: Research article

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  15. Finite element analysis (FEA) is an important tool during the spinal biomechanical study. Irregular surfaces in FEA models directly reconstructed based on imaging data may increase the computational burden and...

    Authors: Jingchi Li, Chen Xu, Xiaoyu Zhang, Zhipeng Xi, Shenglu Sun, Ke Zhang, Xiaoyang Fang, Lin Xie, Yang Liu and Yueming Song

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:498

    Content type: Research article

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  16. The purpose of this study was to evaluate and compare the long-term clinical outcomes between the total patellectomy and osteosynthesis with tension band wiring in patients with highly comminuted patella fract...

    Authors: Xiangtian Deng, Lian Zhu, Hongzhi Hu, Jian Zhu, Weijian Liu, Junzhe Zhang, Sifan Yang, Zhipeng Ye, Haitao Guan, Boyu Zhang, Xiaodong Cheng and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:497

    Content type: Research article

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  17. Calcium phosphate-based bone graft substitutes are used to facilitate healing in bony defects caused by trauma or created during surgery. Here, we present an injectable calcium phosphate-based bone void filler...

    Authors: Jacob T. Landeck, William R. Walsh, Rema A. Oliver, Tian Wang, Mallory R. Gordon, Edward Ahn and Colin D. White

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:496

    Content type: Research article

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  18. This study investigates whether three-dimensional (3D) printing-assisted revision total hip/knee arthroplasty could improve its clinical and radiological outcomes and assess the depth and breadth of research c...

    Authors: Rui Zhang, Jiajun Lin, Fenyong Chen, Wenge Liu and Min Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:495

    Content type: Systematic review

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  19. Myelomeningocele (MMC) is the most common and severe form of spina bifida and imposes a significant burden on patients and the healthcare system. Recently, the multidisciplinary management of MMC has become po...

    Authors: Parnian Shobeiri, Ana Presedo, Amirali Karimi, Sara Momtazmanesh, Fardis Vosoughi and Mohammad Hossein Nabian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:494

    Content type: Systematic review

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  20. The aims of current study were to present the clinical outcomes in patients with pediatric tibia shaft fractures who were treated with unilateral external fixation combined with joystick for fracture reduction...

    Authors: Xinhui Wang, Zhe Zhang, Xizhi Hou, Bao Wang, Yongdong Li and Tao Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:493

    Content type: Research article

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  21. This study aimed to evaluate the clinical efficacy of femoral head and neck fenestration combined with autologous bone mixed with β-tricalcium phosphate porous bioceramic bone (light bulb procedure) through Or...

    Authors: Dawei Liang, Jia Pei, Leilei Zhang, Haonan Ling, Youwen Liu and Xiantao Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:492

    Content type: Research article

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  22. This study aimed to explore the epidemiological and microbiological characteristics of fracture-related infection (FRI), analyze the drug resistance characteristics of major pathogens, and provide timely and r...

    Authors: Baisheng Wang, Xiaoguang Xiao, Jingdong Zhang, Wenfeng Han, Salad Abdirahman Hersi and Xin Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:490

    Content type: Research article

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  23. This study was designed to compare the ultimate tensile strength and force to 2 mm gap formation among 50% partial, 75% partial, and complete circumferential epitendinous suture with a combination of 4-strand ...

    Authors: Thepparat Kanchanathepsak, Wilarat Wairojanakul, Sorasak Suppaphol, Ittirat Watcharananan, Panithan Tuntiyatorn and Tulyapruek Tawonsawatruk

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:489

    Content type: Research article

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  24. Total hip arthroplasty (THA) has been used for over five decades for treating hip osteoarthritis. THA is a surgical procedure associated with prolonged hospital length of stay (LOS). The aim of this study was ...

    Authors: Raul Frankllim de Carvalho Almeida, Humberto Oliveira Serra and Liszt Palmeira de Oliveira

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:488

    Content type: Research article

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  25. The correlations between patient characteristics and early postoperative functional performances after total knee arthroplasty have not been adequately studied. The purpose of this study was to clarify the eff...

    Authors: Yoshinori Ishii, Hideo Noguchi, Junko Sato, Ikuko Takahashi, Hana Ishii, Ryo Ishii, Kei Ishii and Shin-Ichi Toyabe

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:487

    Content type: Research article

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  26. This retrospective study aimed to analyze the influence of Modic changes (MCs) on the clinical and radiographic outcomes of transforaminal lumbar interbody fusion with hybrid graft.

    Authors: Jiaxun Jiao, Jiaqi Li, Yun Luo and Wei Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:486

    Content type: Research article

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  27. The anterolateral muscle-sparing total hip arthroplasty (THA) in the supine position is advantageous owing to the very low-dislocation rate and excellent leg length discrepancy control. However, femur exposure...

    Authors: Hidetatsu Tanaka, Norikazu Yamada, Hiroaki Kurishima, Yu Mori, Takashi Sakamoto, Masamizu Oyama and Toshimi Aizawa

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:485

    Content type: Research article

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  28. We aimed to determine the ideal surgical timing in the first 24 hours after admission to the hospital of pediatric supracondylar humerus fractures (SHF) that do not require emergent intervention.

    Authors: Mustafa Caner Okkaoglu, Fırat Emin Ozdemir, Erdi Ozdemir, Mert Karaduman, Ahmet Ates and Murat Altay

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:484

    Content type: Research article

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  29. Children with early-onset scoliosis living in high-altitude areas have severe deformities and poor nutritional status. However, no reports on early-onset scoliosis treatment using traditional growing rods in s...

    Authors: Haijun Jiang, Junrui Jonathan Hai, Peng Yin, Qingjun Su, Shiqi Zhu, Aixing Pan, Yunsheng Wang and Yong Hai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:483

    Content type: Research article

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  30. Bone marrow infiltration (BMI) is a devastating stage of paediatric lymphoma. Prompt diagnosis of BMI in newly diagnosed paediatric lymphoma patients is critical but can be very challenging at present.

    Authors: Zhizhuo Li, Chengxin Li, Bingrong Chen, Lijun Shi, Fuqiang Gao, Peixu Wang and Wei Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:482

    Content type: Systematic review

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  31. Thumb duplication is a very common congenital malformation. This study describes and compares the phenotypic manifestations of polydactyly between southwest and northeast China. However, previous studies had a...

    Authors: Yingling Yao, Haolin Zhou, Lianyong Li and Guoxin Nan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:481

    Content type: Research article

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  32. The role of open cerclage wiring in comminuted femoral shaft fracture treatment with intramedullary nails remains unclear. Here, we analyzed the effect of open cerclage wiring and the risk factors for nonunion...

    Authors: Tzu-Hao Wang, Hao-Chun Chuang, Fa-Chuan Kuan, Chih-Kai Hong, Ming-Long Yeh, Wei-Ren Su and Kai-Lan Hsu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:480

    Content type: Research article

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  33. Minocycline black bone disease is a rare finding that can cause concern when unexpectedly encountered during routine arthroplasty. Prolonged minocycline use can cause selective staining of subchondral bone, wh...

    Authors: William Steadman, Zak Brown and Christopher J. Wall

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:479

    Content type: Systematic review

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  34. The aim of anterior cruciate ligament reconstruction (ACLR) is to restore the function of the knee joint, protect the cartilage, and reduce the occurrence of osteoarthritis. However, due to the structural limi...

    Authors: DingYuan Fan, Jia Ma and Lei Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:478

    Content type: Systematic review

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  35. Femoral neck fractures (FNF) are frequent in the elderly population, and surgical management is indicated in the vast majority of cases. Osteosynthesis is an alternative to arthroplasty for non-displaced FNF. ...

    Authors: Oscar Vazquez, Axel Gamulin, Didier Hannouche and Wilson Belaieff

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:477

    Content type: Research article

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  36. Vertebral augmentation (VA) techniques are used to treat acute osteoporotic vertebral compression fractures (OVCFs). However, the incidence of recurrent vertebral fractures after VA is controversial. Various f...

    Authors: He Zhao, Yan He, Jun-Song Yang, Wei Bao, Jian Chen, Ji-Jun Liu, Qing-Da Li, Peng Liu, Bing Qian, Yuan-Ting Zhao and Ding-Jun Hao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:476

    Content type: Research article

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  37. Previous reports confirmed early spinal fusion may compromise pulmonary function and thoracic development in skeletal immature patients with scoliosis. However, the different effects in patients with various R...

    Authors: Xiaolin Xu, Shengru Wang, Yang Yang, You Du, Guanfeng Lin and Jianguo Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:475

    Content type: Research article

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  38. The optimal internal fixation strategy for vertical femoral neck fractures (VFNFs) in nongeriatric patients remains uncertain. Therefore, the purpose of this study was to compare the clinical prognoses and und...

    Authors: Dajun Jiang, Shi Zhan, Qianying Cai, Hai Hu and Weitao Jia

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:473

    Content type: Research article

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  39. Rheumatic arthritis (RA) is an autoimmune disease with bad effects. Recent researches have shown that circular RNAs (circRNAs) could affect the progress of RA, but the mechanism still indistinct. In this work,...

    Authors: Xiaofeng Wang, Zhiwen Zhang, Haofeng Liang, Ruixiong Chen and Yuliang Huang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:472

    Content type: Research article

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  40. Osteosarcoma (OS) is a type of bone cancer that occurs in children and adolescents at a rate of 5%. The purpose of this study is to explore the lncRNA GNAS-AS1 expression profile, prognosis significance in OS,...

    Authors: Zhanhu Mi, Yanyun Dong, Zhibiao Wang and Peng Ye

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:470

    Content type: Research article

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  41. Enhanced Recovery After Surgery (ERAS) is a multimodal approach to perioperative care that aims to reduce patient perioperative complications, accelerate patient recovery, and improve patient satisfaction by r...

    Authors: Wenhao Zhu, Yinjie Yan, Yijin Sun, Zhaoxiang Fan, Niangkang Fang, Yunlu Zhang, Mengchen Yin, Hongbo Wan, Wen Mo, Wei Lu and Xuequn Wu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:469

    Content type: Research article

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  42. In painful epicondylitis, previous studies reported deficiencies in elbow proprioception. In line, proprioceptive training of the lower limb has been reported substantial beneficial in a number of indications....

    Authors: B. Schiffke-Juhász, K. Knobloch, P. M. Vogt and L. Hoy

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:468

    Content type: Research article

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  43. This study compared the stability and clinical outcomes of modified pedicle screw-rod fixation (MPSRF) and anterior subcutaneous internal pelvic fixation (INFIX) for the treatment of anterior pelvic ring fract...

    Authors: Zhi-Hong Pan, Fan-Cheng Chen, Jun-Ming Huang, Cheng-Yi Sun and Sheng-Long Ding

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:467

    Content type: Research article

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