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  1. A variety of mutations in the largest human gene, dystrophin, cause a spectrum from mild to severe dystrophin-associated muscular dystrophies. Duchenne (DMD) and Becker (BMD) muscular dystrophies are located a...

    Authors: Nader Salari, Behnaz Fatahi, Elahe Valipour, Mohsen Kazeminia, Reza Fatahian, Aliakbar Kiaei, Shamarina Shohaimi and Masoud Mohammadi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:96
  2. Serum lipids are highly inheritable and play a major role in bone health. However, the relationship between high-density lipoprotein cholesterol (HDL-C) and bone mineral density (BMD) remains uncertain. The go...

    Authors: Ruijie Xie, Xiongjie Huang, Qianlong Liu and Mingjiang Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:92
  3. To evaluate the relationship of postoperative cervical axial pain with different vertebral distraction methods used during ACDF procedures in cervical spondylosis patients.

    Authors: Chen Xu, Ruizhe Wang, Jingchi Li, Huajian Zhong, Zifang Zhang, Cheng Cui, Baifeng Sun, Ye Tian, Huajiang Chen, Xiaolong Shen, Yang Liu and Wen Yuan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:91
  4. The incidence of osteoporosis and osteoporotic fractures is increasing every year. Traditional Chinese Medicine (TCM) can shed new light on the treatment of osteoporosis. This study aimed to explore the role a...

    Authors: Wei Guo, Xiao-guang Yang, Yu-lin Shi and Hong Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:90
  5. The present study investigates the effects of Juglans regia L. (walnut, JRL) leaves extract on osteogenesis of human bone marrow mesenchymal stem cells (hBMSCs).

    Authors: Xianlun Pang, Zhendong Zhong, Feng Jiang, Jian Yang and Hai Nie
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:88
  6. With regard to the ceramic hip joint implant, given the concerns in ceramic about the alumina brittleness and zirconia instability, is there any alternative material solution for the orthopedic implant? Beyond...

    Authors: Xiangpeng Kong, Xiaosu Hu and Wei Chai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:87
  7. Steroid-induced osteonecrosis of the femoral head (SONFH) is a refractory orthopaedic hip joint disease that occurs in young- and middle-aged people. Previous experimental studies have shown that autophagy mig...

    Authors: Xue-Zhen Liang, Di Luo, Yan-Rong Chen, Jia-Cheng Li, Bo-Zhao Yan, Yan-Bo Guo, Ming-Tao Wen, Bo Xu and Gang Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:86
  8. Given the possibility of inadvertent bacterial contamination of salvaged blood, the use of cell salvage is relatively contraindicated in cases of reimplantation for chronic hip periprosthetic joint infection (...

    Authors: Zunhan Liu, Xuetao Yang, En-Ze Zhao, Xufeng Wan, Guorui Cao and Zongke Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:85
  9. Calcaneal apophysitis, or Sever's disease, is the most common cause of heel pain in childhood and adolescence. It is regarded as an overuse syndrome. Studies on the incidence of calcaneal apophysitis in young ...

    Authors: Patrick Belikan, Lars-Christopher Färber, Frédéric Abel, Tobias E. Nowak, Philipp Drees and Stefan G. Mattyasovszky
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:83
  10. Abnormal metabolic features have been previously described in adolescent idiopathic scoliosis (AIS) patients. As an important regulator involved in energy metabolism, DPP-4 activity was reported to be remarkab...

    Authors: Zhicheng Dai, Bingchuan Xue, Leilei Xu, Zhenhua Feng, Zhichong Wu, Yong Qiu and Zezhang Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:82
  11. Distal chevron osteotomy is commonly used for the operative treatment of hallux valgus (HV). However, there are several operative procedures that can be used to treat HV. The aim of this meta-analysis was to c...

    Authors: Pablo Clemente, Gonzalo Mariscal and Carlos Barrios
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:80
  12. Medial opening wedge high tibial osteotomy (MOWHTO) changes the knee joint inclination in the coronal plane, which can be compensated by the ankle joint. Once there is a decompensated knee joint obliquity, it ...

    Authors: Tzu-Hao Tseng, Han-Ying Wang, Shi-Chien Tzeng, Kuan-Hung Hsu and Jyh-Horng Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:79
  13. This study aims to introduce the “tripod” technique using cannulated compression screw and two anti-rotational K-wires for treatment of unstable scaphoid waist fracture nonunion, and to compare it with the sin...

    Authors: Xiaoran Zhang, Li Wang, Xuelin Ma, Fengyu Wang, Wenxu Duan and Xinzhong Shao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:78
  14. The objective of this study was to investigate the prevalence of preoperative deep venous thrombosis (DVT) in the pelvic cavity and lower extremities following pelvic and acetabular fractures and to identify t...

    Authors: Weiguang Zhao, Jianlong Zhao, Tiantian Liu, Zhenwu Liu, Li Liu and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:77
  15. Disorders involving the musculoskeletal system are often identified with short stature and a range of orthopedic problems. The clinical and genetic heterogeneity of these diseases along with several characteri...

    Authors: Gayatri R. Iyer, Roshan Kumar, Subhadra Poornima, Aruna Priya Kamireddy, Keerthi Konda Juturu, Lekhangda Bhatnagar, Srinka Arora, Vaishnavi Suresh, Prashant R. Utage, Sarah Bailur, Akhilesh N. Pujar and Qurratulain Hasan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:76
  16. Minimally invasive surgery for carpal tunnel syndrome has been consistently the mainstay of treatment. In this study, we developed a novel bush hook via a mini-transverse incision at proximal wrist crease to s...

    Authors: Dongyue Wang, Tianxiao Ma, Yuqing Hu, Xiaocui Zhao and Lihua Song
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:75
  17. Osteosarcoma is a type of bone malignancy that mainly occurred in teenagers. This investigation is aimed to clarify the effect of long non-coding RNA (lncRNA) LINC00662 on the proliferation, migration, and inv...

    Authors: Bin Wang, Zhengfeng Xu, Xiuhui Wang, Shengli Xia, Pan Cai, Minghui Wang and Zhenchao Gao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:74
  18. Postoperative acromioclavicular (AC) ligament deficiency has been identified as a common cause of failure after isolated coracoclavicular reconstruction. The two-bundle arrangement of the acromioclavicular lig...

    Authors: Ausberto Velasquez Garcia, Farid Salamé Castillo, Max Ekdahl Giordani and Joaquin Mura Mardones
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:73
  19. For oblique metacarpal shaft fracture, if anatomical reduction is achieved through conservative cast immobilization rather than stable fixation, bone malrotation can easily occur, resulting in severe loss in h...

    Authors: Yung-Cheng Chiu, Tsung-Yu Ho, Cheng-En Hsu, Yen-Nien Ting, Ming-Tzu Tsai and Jui-Ting Hsu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:72
  20. The retrospective study was designed to compare the effectiveness and safety of acute normovolemic hemodilution (ANH), tranexamic Acid (TXA), and a combination of ANH and TXA in lumbar spinal fusion surgery.

    Authors: Yang Li, Yan Zhang and Xiutong Fang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:71
  21. Osteoarthritis (OA) is the most prevalent degenerative joint disease. In vitro experiments are an intuitive method used to investigate its early pathogenesis. Chondrocyte inflammation models in rats and mice a...

    Authors: Dao-Fang Ding, Yan Xue, Jun-Peng Zhang, Zeng-Qiao Zhang, Wen-Yao Li, Yue-Long Cao and Jian-Guang Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:70
  22. The arthroscopic modified Broström procedure, with repair of the anterior talofibular ligament and extensor retinaculum, produces good functional outcomes in patients with chronic lateral ankle instability (CL...

    Authors: Shi-Ming Feng, Jie Chen, Chao Ma, Filippo Migliorini, Francesco Oliva and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:69
  23. Titanium and its alloys have been widely employed for bone tissue repair and implant manufacturing. The rapid development of three-dimensional (3D) printing technology has allowed fabrication of porous titaniu...

    Authors: Yifei Gu, Yi Sun, Sohaib Shujaat, Annabel Braem, Constantinus Politis and Reinhilde Jacobs
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:68
  24. Chronic Achilles tendon rupture is associated with persistent weakness at push-off with the affected foot and poor balance, resulting in significant alterations to normal gait. Surgical repair is the most comm...

    Authors: Anna Nordenholm, Eric Hamrin Senorski, Olof Westin, Katarina Nilsson Helander, Michael Möller, Jón Karlsson and Roland Zügner
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:67
  25. Angular stable plates were introduced two decades ago as a promising treatment for fixation of displaced fractures of the proximal humerus (PHF). However, high rates of adverse events and reoperations have bee...

    Authors: Ingrid Bønes, Anna Cecilie Karlberg, Maria Liljeholm, Alexander Nilsskog Fraser, Jan Erik Madsen and Tore Fjalestad
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:66
  26. The aim of this study was to appraise the effects of motor imagery on the functional performance improvement among total knee arthroplasty patients systematically. We hypothesized a relatively greater recovery...

    Authors: Ran Li, Jubao Du, Kun Yang, Xue Wang and Wenjiao Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:65
  27. Spinopelvic mobility gained increased attention as a contributing factor for total hip arthroplasty (THA) instability. However, it is unknown how a pre-existing THA affects spinopelvic mobility. Therefore, a p...

    Authors: Maximilian Muellner, Luis Becker, Zhen Wang, Zhouyang Hu, Sebastian Hardt, Matthias Pumberger and Henryk Haffer
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:64
  28. Patellar dislocations in patients presenting with recurrent patellofemoral instability can damage the surrounding structures, limiting patient’s participation to recreational activities and quality of life. Th...

    Authors: Filippo Migliorini, Emanuela Marsilio, Francesco Oliva, Jörg Eschweiler, Frank Hildebrand and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:63
  29. High tibial osteotomy (HTO) has been used for the treatment of patients with knee osteoarthritis. However, the successful implementation of HTO requires precise intraoperative positioning, which places greater...

    Authors: Zhuang Miao, Songlin Li, Desu Luo, Qunshan Lu and Peilai Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:62
  30. This study assessed the accuracy of robotic-arm-assisted total knee arthroplasty (RATKA) for bone resection, component size prediction, implant placement, and limb alignment.

    Authors: Chenkai Li, Zian Zhang, Guanrong Wang, Chun Rong, Wanping Zhu, Xinzhe Lu, Yikai Liu and Haining Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:61
  31. While the precise measurement of the range of motion (ROM) of the elbow joint is important for clinical assessment and rehabilitation, problems include low accuracy and reproducibility in goniometer measuremen...

    Authors: Kohei Yamaura, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takeshi Kataoka, Takashi Kurosawa, Shintaro Mukohara, Yuichi Hoshino, Takahiro Niikura, Kouki Nagamune and Ryosuke Kuroda
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:60
  32. The empirical use of tranexamic acid (TXA) for bleeding remains controversial because of the distinct fibrinolytic phenotypes observed after injury. This study sought to assess the efficacy of postoperative TX...

    Authors: Jiacheng Liu, Han Wang, Xiangdong Wu, Yiting Lei and Wei Huang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:59
  33. Surgical management of adolescent idiopathic scoliosis (AIS) can be performed using standard posterior spinal fusion (PSF) or with a posterior minimally invasive approach. Minimally invasive scoliosis surgery ...

    Authors: Honghao Yang, Xiangyuan Jia and Yong Hai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:58
  34. This study retrospectively analyzed and evaluated the potential correlations of serum calcium, serum phosphorus, and calcium-phosphorus product (Ca–P product) with the incidence of osteoporotic vertebral compr...

    Authors: Pu Ying, Mingjia Gu, Xiaowei Jiang, Yue Xu, Lu Tong, Yi Xue, Qiang Wang, Zhihui Huang, Wenge Ding and Xiaoyu Dai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:57
  35. Elderly acetabular fractures are one of the more difficult types of fractures to resolve. For patients at this age, the more common type of fracture is comminuted. How to better fix this type of fracture has a...

    Authors: Guixiong Huang, Kaifang Chen, Yulong Wang and Xiaodong Guo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:56
  36. We evaluated the radiologic and clinical outcomes of a lateral incision single plate with and a single-incision double plating in elderly patients with osteoporotic distal femoral fractures.

    Authors: Dae Jin Nam, Min Seok Kim, Tae Ho Kim, Min Woo Kim and Suc Hyun Kweon
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:55
  37. Circular RNAs (circRNAs) have emerged as vital regulators in the development of rheumatoid arthritis (RA). In this study, we aimed to explore the functions and mechanisms of circ_0001947 in RA.

    Authors: Yang Yang, Shudian Lin, Zhou Yang, Yanyan Huang and Feng Zhan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:54
  38. Osteoclast cell increase is a major risk factor for osteoporosis and degenerative bone and joint diseases. At present, RANKL and M-CSF are commonly used to induce osteoclastogenesis. Thioacetamide (TAA) can le...

    Authors: XiaoLi Jin, Yang Li, Yayang Yang, Hao Shen, Jin Chen, Bin Xu and Jian Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:53
  39. Although the use of intraoperative computed tomography (CT)-based navigation systems is unlikely to cause intraoperative contamination more than the use of intraoperative fluoroscopy, the association between i...

    Authors: Gentaro Kumagai, Kanichiro Wada, Sunao Tanaka, Toru Asari, Yohshiro Nitobe and Yasuyuki Ishibashi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:52
  40. The treatment of comminuted posterior wall acetabular fractures remains challenging due to the difficulty in understanding of fracture patterns and lack of appropriate preoperative planning process. Virtual pr...

    Authors: Yifan Zheng, Jianan Chen, Siyu Yang, Xi Ke, Dan Xu, Guodong Wang, Xianhua Cai and Ximing Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:51
  41. To identify medial open-wedge high tibial osteotomy (MOWHTO) prognostic factors with wedge-shaped spacer implantation (spacer-type MOWHTO) for varus medial compartment knee osteoarthritis.

    Authors: Fengkun Wang, Wenru Ma, Jinli Chen, Wenbin Cong, Yingze Zhang, Tengbo Yu and Yi Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:50
  42. Adipose-derived mesenchymal stem cells (ADSCs), as seed cells for tendon tissue engineering, are promising for tendon repair and regeneration. But for ADSCs, diverse oxygen tensions have different stimulatory ...

    Authors: Xing Guo, Denghua Huang, Dan Li, Longfei Zou, Hui Lv, Yuanhui Wang and Meiyun Tan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:49
  43. Knee osteoarthritis (KOA) is based on degenerative pathological changes. miR-155 is involved in regulating KOA. This study estimated the mechanism of miR-155 in mouse KOA chondrocytes.

    Authors: Gen Li, Lijun Xiu, Xiaoyun Li, Lisha Ma and Jihui Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:48
  44. The clinical outcomes of using a zero-profile for anterior cervical decompression and fusion were evaluated by comparison with anterior cervical plates.

    Authors: Tingxin Zhang, Nana Guo, Gang Gao, Hao Liu, Yanhong Li, Feng Gao, Qingxin Zhang, Xiaoyang Tao, Wupeng Yang and Yongjiang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:47
  45. This study aimed to evaluate the short-term effect of radial shockwave on the median nerve pathway as a new model method in patients with mild-to-moderate carpal tunnel syndrome.

    Authors: Atieh Habibzadeh, Roghayeh Mousavi-Khatir, Payam Saadat and Yahya Javadian
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:46
  46. Fifth metatarsal base fracture (fifth MBF) and lateral collateral ankle ligament (LCAL) injury are mainly caused by plantar flexion and inversion of the foot. However, there is no relevant report on the incide...

    Authors: Hongbin Cao, Nan Li, Guixin Wang and Jinquan He
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:45
  47. Surgical treatment is advised for unstable distal clavicle fractures (UDCFs). Various kinds of internal fixation methods have been used, but the best fixation is still controversial.

    Authors: Yinglong Xu, Xiaobo Guo, Hui Peng, Hai Dai, Zonggui Huang and Jinmin Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:43

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