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  1. The aim of this study is to explore the effects of TGF-β1 on autophagy and apoptosis induced by exogenous hydrogen peroxide (H2O2) in annulus fibrosus (AF) cells and possible signal pathways involved in this proc...

    Authors: Binbin Ni, Hao Shen, Wei Wang, Hua Lu and Leisheng Jiang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:241

    Content type: Research article

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  2. Evidence on antibiotic-loaded bone cement remains too vague to guide kyphoplasty in patient care. We clinically evaluated the properties and benefits of a new low viscosity polymethylmethacrylate (PMMA) bone c...

    Authors: Maciej Opalko, Hans Bösebeck and Sebastian Vogt

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:238

    Content type: Research article

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  3. Meniscal horns are important structures of meniscus, and longitudinal tears of these places could significantly change the load distribution among the knee joint. Few studies concerned the stress concentrated ...

    Authors: Kaijia Zhang, Lan Li, Longfei Yang, Jianping Shi, Liya Zhu, Huixin Liang, Xingsong Wang, Xianfeng Yang and Qing Jiang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:237

    Content type: Research article

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  4. The aim of this study was to evaluate the intraoperative revision rate and reasons for revision following 3D imaging in the management of dislocated articular tibial plateau fractures based on a large patient ...

    Authors: Nils Beisemann, Holger Keil, Benedict Swartman, Marc Schnetzke, Jochen Franke, Paul Alfred Grützner and Sven Y. Vetter

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:236

    Content type: Research article

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  5. Excessive blood loss caused by total joint arthroplasty (TJA) often increases the requirement for blood transfusion, which is associated with adverse outcomes. The purpose of this study was to determine the re...

    Authors: Tao Jiang, Kai Song, Yao Yao, Pin Pan and Qing Jiang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:235

    Content type: Research article

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  6. Acute injuries of the hamstring muscle complex (HMC) type 3b (interfascicle/bundle-tear) are frequently observed in various sports disciplines both in elite and recreational sport. The treatment of choice of a...

    Authors: Javier Crupnik, Santiago Silveti, Natalia Wajnstein, Alejandro Rolon, Alisa Vollhardt, Peter Stiller and Christoph Schmitz

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:234

    Content type: Study protocol

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  7. The purpose of this multicentre, retrospective study was to evaluate the safety and efficacy of different surgical approaches for treating thoracolumbar tuberculosis.

    Authors: Yong Tang, Wen-jie Wu, Sen Yang, Dong-Gui Wang, Qiang Zhang, Xun Liu, Tian-Yong Hou, Fei Luo, Ze-hua Zhang and Jian-zhong Xu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:233

    Content type: Research article

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  8. Pelvic tumors are usually resected through the utilitarian pelvic incision, an extended ilioinguinal/iliofemoral approach. The pararectus approach, an intrapelvic anatomical approach with extraperitoneal acces...

    Authors: Christophe Kurze, Marius Johann Baptist Keel, Attila Kollár, Klaus Arno Siebenrock and Frank Michael Klenke

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:232

    Content type: Research article

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  9. This study aimed to investigate the effects of stromal cell-derived factor-1 (SDF-1) on biphasic ceramic-like biologic bone (BCBB) in vivo on the repair of large segment bone defect in rabbits.

    Authors: Fuke Wang, Guiran Yang, Yu Xiao, Chuan He, Guofeng Cai, En Song and Yanlin Li

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:231

    Content type: Research article

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  10. For coronal shear fractures of humeral capitellum, the lateral approach is the most commonly used surgical approach. However, exposure range of the anterior aspect of the distal humerus is inadequate. The ante...

    Authors: Tengbo Yu, Hao Tao, Fenglei Xu, Yanling Hu, Chengdong Zhang and Guangjie Zhou

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:230

    Content type: Research article

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  11. Vertebroplasty is the most widely used method for treating osteoporotic vertebral compression fractures (OVCF). During this procedure, bone cement is injected into the vertebral body. Fracture and additional f...

    Authors: Le Hu, Hao Sun, Hua Wang, Jun Cai, Yuping Tao, Xinmin Feng and Yongxiang Wang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:228

    Content type: Research article

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  12. The past century has witnessed the rapid development of operation technique, surgical instruments, and knowledge of the diseases in orthopedics. In the academic history, a number of classic papers boosted the ...

    Authors: Yunzhu Li, Gang Xu, Xiao Long and Yuh-Shan Ho

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:227

    Content type: Research article

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  13. Avascular necrosis of the femoral head (ANFH) is a severe complication after high-dose glucocorticoid (GC) administration. The pathogenesis of GC-induced ANFH remains unclear. Though the important role of endo...

    Authors: Peng Ding, Wen Zhang, Qiyuan Tan, Chen Yao and Sen Lin

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:226

    Content type: Research article

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  14. Several hydroxyapatite (HA)-coated femoral stems from a single manufacturer were identified to have aseptically loosened at mid-term follow-up despite prior radiographic appearance of osseointegration. Possibl...

    Authors: Trevor Gascoyne, Bryan Flynn, Thomas Turgeon and Colin Burnell

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:225

    Content type: Research article

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  15. Increased signal intensity (ISI) on T2-weighted magnetic resonance imaging (MRI) often indicates severe compression in patients with cervical myelopathy (CM). The optimal surgical approach for CM patients with...

    Authors: Yuan Xu, Feng Chen, Yipeng Wang, Jianguo Zhang and Jianhua Hu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:224

    Content type: Research article

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  16. The accelerometer-based navigation (ABN) system is an emerging navigation system for total knee arthroplasty (TKA). This study aimed to determine whether the ABN system could improve the accuracy of mechanical...

    Authors: Xiang Gao, Yu Sun, Zhao-He Chen, Tian-Xu Dou, Qing-Wei Liang and Xu Li

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:223

    Content type: Research article

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  17. Femoroacetabular impingement (FAI) is associated with decreased hip function and early hip osteoarthritis. Surgical treatment is often required to halt the process of mechanical degeneration. The study investi...

    Authors: Cheng-Ta Wu, Mohammed Mahameed, Po-Chun Lin, Yu-Der Lu, Feng-Chih Kuo and Mel S. Lee

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:222

    Content type: Research article

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    The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2019 14:251

  18. The aim of this study was to determine the differences and consistencies in the morphological and angular interpretations of standard USG images. Therefore, it was aimed to show the correlations of orthopaedic...

    Authors: Ozgun Karakus, Ozgur Karaman, Ahmet Sinan Sari, Mehmet Mufit Orak and Hasan Hilmi Muratli

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:221

    Content type: Research article

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  19. The aim of our study was to investigate failure rates of reconstruction plate and non-reconstruction plate, and find the best strategy for implant selection for different fracture types for midshaft clavicular...

    Authors: Yung-Cheng Chiu, Kui-Chou Huang, Cheng-Min Shih, Kun-Tsan Lee, Kun-Hui Chen and Cheng-En Hsu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:220

    Content type: Research article

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  20. High tibial osteotomy (HTO) is a common treatment for moderate osteoarthritis of the medial compartment in the knee joint by the translation of the force center toward the lateral compartment. However, the sta...

    Authors: Yong-Gon Koh, Jin-Ah Lee, Hwa-Yong Lee, Heoung-Jae Chun, Hyo-Jeong Kim and Kyoung-Tak Kang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:219

    Content type: Research article

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  21. There are concerns regarding the complications encountered during the learning curve when switching to a direct anterior approach (DAA) for total hip arthroplasty (THA). The purpose of our study is to report o...

    Authors: Xiangpeng Kong, Luis Grau, Alvin Ong, Charlie Yang and Wei Chai

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:218

    Content type: Research article

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  22. Bernese periacetabular osteotomy (PAO) has been shown to be applicable as a hip-preserving technique for the treatment of developmental dysplasia of the hip (DDH). The approach could be designed preoperatively...

    Authors: Xuyi Wang, Shixian Liu, Jianping Peng, Zhonglian Zhu, Linlin Zhang, Jianzhong Guan and Xiaodong Chen

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:217

    Content type: Research article

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  23. This study assessed clinical and radiographic outcomes of oblique lumbar interbody fusion (OLIF) in comparison with posterior reoperation for adjacent segment disease (ASD).

    Authors: Cong Jin, Minghua Xie, Lei He, Wenbin Xu, Weiqi Han, Wengqing Liang and Yu Qian

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:216

    Content type: Research article

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  24. Questions remain, mainly concerning whether tranexamic acid (TXA) is truly safe since all available trials were underpowered to identify clinically important differences. The objective of this study is to eval...

    Authors: Xiang-Dong Wu, Yu Chen, Mian Tian, Yao He, Yu-Zhang Tao, Wei Xu, Qiang Cheng, Cheng Chen, Wei Liu and Wei Huang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:214

    Content type: Research article

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  25. The aims of this study were to propose a novel implant design for the proximal interphalangeal joint (PIPJ) of the hand using a rolling contact joint (RCJ) mechanism and to derive an optimal implant design bas...

    Authors: Seok Woo Hong, Junsuk Yoon, Yong-Jae Kim and Hyun Sik Gong

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:212

    Content type: Research article

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  26. Treatment of idiopathic congenital talipes equinovarus (CTEV) is challenging for pediatric orthopedic surgeons. The Ponseti method is an effective protocol for treatment due to its technique of manipulation, c...

    Authors: Yuxi Su, Yan Xie, Xiaopeng Kang and Guoxin Nan

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:211

    Content type: Research article

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  27. Thoracic ossification of the posterior longitudinal ligament (T-OPLL) can cause thoracic spinal stenosis, which results in intractable myelopathy and radiculopathy. The etiology of T-OPLL is unknown and the co...

    Authors: Peng Wang, Xiaoguang Liu, Xiao Liu, Chao Kong, Ze Teng, Yunlong Ma, Lei Yong, Chen Liang, Guanping He and Shibao Lu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:210

    Content type: Research article

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  28. Enhanced recovery after surgery (ERAS) has rapidly gained popularity among hip or knee arthroplasty area which can decrease hospital length of stay (LOS). However, limited data exist regarding its safety and e...

    Authors: Yan Kang, Jianxing Liu, Haihong Chen, Wang Ding, Jianqing Chen, Bin Zhao and Xiaofan Yin

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:209

    Content type: Research article

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  29. In the original publication of this article [1], the Table 1-5 were missing due to a mistake in the copy-editing stage

    Authors: Shuai Xu, Yan Liang, Fanqi Meng, Kaifeng Wang and Haiying Liu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:207

    Content type: Correction

    Published on:

    The original article was published in Journal of Orthopaedic Surgery and Research 2019 14:160

  30. The positive effects of grape seed proanthocyanidin extract (GSPE) on bone health, which is a potent antioxidant, are known but its effects on fracture healing are not sufficiently covered in the literature. T...

    Authors: Murat Gurger, Erhan Yilmaz, Seval Yilmaz, Gokhan Once, Mustafa Konuk, Emre Kaya, Yakup Say, Gokhan Artas and Hakan Artas

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:206

    Content type: Research article

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  31. Osteonecrosis of the femoral head (ONFH) is a disabling disease. Early treatment is crucial to the prognosis of the disease. Core decompression (CD) is one of the most commonly used methods for the treatment o...

    Authors: Guozong Wang, Yi Li, Tiantong Sun, Congcong Wang, Li Qiao, Yi Wang, Kangkang Dong, Tao Yuan, Jiazheng Chen, Guanqiao Chen and Shui Sun

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:204

    Content type: Research article

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  32. It is known that mortality after hip fracture increases compared to the general population; the trend in mortality is a controversial issue.

    Authors: Olalla Guzon-Illescas, Elia Perez Fernandez, Natalia Crespí Villarias, Francisco Javier Quirós Donate, Marina Peña, Carlos Alonso-Blas, Alberto García-Vadillo and Ramon Mazzucchelli

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:203

    Content type: Research article

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  33. The purpose of this study was to compare 2-year BMI changes between patients undergoing simultaneous bilateral total knee arthroplasty (TKA), staged bilateral TKA, and unilateral TKA. We also sought to determi...

    Authors: Pengfei Zan, Jie J. Yao, Kaiyuan Liu, Dong Yang, Weixu Li and Guodong Li

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:200

    Content type: Research article

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  34. We focused on the therapeutic effects of the stable gastric pentadecapeptide BPC 157 in spinal cord injury using a rat model. BPC 157, of which the LD1 has not been achieved, has been implemented as an anti-ul...

    Authors: Darko Perovic, Danijela Kolenc, Vide Bilic, Nenad Somun, Domagoj Drmic, Esmat Elabjer, Gojko Buljat, Sven Seiwerth and Predrag Sikiric

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:199

    Content type: Research article

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  35. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) are one of the most potent adult stem cells, capable of differentiating into bone, cartilage, adipose, muscle, and others. An innovative autologous AT-MS...

    Authors: Dror Ben-David, Bettina Fishman, Guy Rubin, Atara Novak, Ilana Laevsky, Avinoam Kadouri, Yasmin Nishri Katz, Ora Burger, Asaph Zaretsky, Noam Bor, Ephraim Tzur, Shai Meretzki and Nimrod Rozen

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:198

    Content type: Research article

    Published on:

  36. Studies have shown that adjacent segment degeneration (ASD) is a common complication after posterior lumbar interbody fusion (PLIF), even a second surgery is required for some patients. It remains unclear whet...

    Authors: Dongyue Li, Yong Hai, Xianglong Meng, Jincai Yang and Peng Yin

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:197

    Content type: Research article

    Published on:

  37. Recent policy initiatives, including Bundled Payments for Care Improvement (BPCI) Initiative by the Centers for Medicare and Medicaid Health Services (CMS), encourage healthcare providers to manage the total e...

    Authors: Ayoade Adeyemi and Paul Trueman

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:196

    Content type: Research article

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  38. Diagnosing distal radioulnar joint (DRUJ) instability remains a challenge as it relies on physical examination. To quantitatively assess DRUJ stability, a pressure-monitor ultrasound system was developed. The ...

    Authors: Yuichi Yoshii, Hiroshi Yuine, Wen-lin Tung and Tomoo Ishii

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:195

    Content type: Technical note

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  39. Infantile patients with congenital scoliosis (CS) can be confronted with increasing risk of mortality and morbidity. To date, the effectiveness of conservative treatment in CS has not been sufficiently investi...

    Authors: Yuwen Wang, Zongxian Feng, Zhichong Wu, Yong Qiu, Zezhang Zhu and Leilei Xu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:194

    Content type: Research article

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  40. The scarf osteotomy is a well-established surgical method for correcting a hallux valgus deformity. It is often combined with an Akin osteotomy. However, clear guidelines defining indication criteria are missi...

    Authors: Gerhard Kaufmann, Maximilian Hofmann, Hanno Ulmer, David Putzer, Philipp Hofer and Dietmar Dammerer

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:193

    Content type: Research article

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  41. Large segmental bone defects can be repaired using the Masquelet technique in conjunction with autologous cancellous bone (ACB). However, ACB harvesting is severely restricted. α-calcium sulfate hemihydrate (α...

    Authors: Zhu Long Meng, Zi Quan Wu, Bi Xin Shen, Hong Bo Li, Yang Yang Bian, De Lu Zeng, Jian Fu and Lei Peng

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:192

    Content type: Research article

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  42. To report the diagnosis, injury mechanisms, and imaging characteristics of hyperextension bicondylar tibial plateau fractures and examine the indications and feasibility of the modified anterior midline incisi...

    Authors: Ruibo Zhao, Zhangyuan Lin, Haitao Long, Min Zeng, Liang Cheng and Yong Zhu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:191

    Content type: Research article

    Published on:

  43. A common complication after rotator cuff repair is postoperative stiffness, which can be reduced by a simple application of an anti-adhesive agent. However, anti-adhesive agents may affect rotator cuff healing...

    Authors: Tae In Kim, Whanik Jung, Jin-Young Chung, Hyunseok Jeong and Sae Hoon Kim

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:190

    Content type: Research article

    Published on:

  44. The adductor tubercle (AT) has been used intraoperatively as a landmark to evaluate the joint line position in knee arthroplasty. The purpose of this study was to determine whether the AT could be clearly iden...

    Authors: Kuang-Ting Yeh, Ing-Ho Chen, Chen-Chie Wang, Wen-Tien Wu, Kuan-Lin Liu and Cheng-Huan Peng

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:189

    Content type: Research article

    Published on:

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