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  1. Fractures in the ankylotic spine may have an insidious presentation but are prone to displace with devastating consequences. The long lever arm of ankylosed spine fragments may lead to pulmonary and great vess...

    Authors: Rina E. Buxbaum, Adi Shani, Hani Mulla, Alon Rod and Nimrod Rahamimov

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:317

    Content type: Research article

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  2. There is great design variability on short femoral stems available on the market. This study aims to evaluate the short-term clinical and radiological results of two different design short femoral stems, both ...

    Authors: I. Tatani, K. Solou, A. Panagopoulos, J. Lakoumentas, A. Kouzelis and P. Megas

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:316

    Content type: Research article

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  3. Preoperative posterior tilt is a risk factor for fixation failure in femoral neck fractures. This study aimed to evaluate the configuration of anterior positioning screw in proximal femoral plating in the trea...

    Authors: Sheng-Bo Nie, Jun-Feng Liu, Jiang-Hua Zhu, Zi-Fei Zhou, Lei Zhang and Long-Po Zheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:315

    Content type: Research article

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  4. Growing evidence has implicated core-binding factor beta (Cbfb) as a contributor to osteoblast differentiation, which plays a key role in fracture healing. Herein, we aimed to assess whether Cbfb affects osteo...

    Authors: Tuanmao Guo, Yanli Xing, Zhongning Chen, Xianhong Wang, Haiyun Zhu, Lan Yang and Yong Yan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:313

    Content type: Research article

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  5. The purpose of this research is to evaluate the risk factors and incidence of pulmonary cement embolism (PCE) during percutaneous vertebroplasty (PVP) or kyphoplasty (PKP) for osteoporotic vertebral compressio...

    Authors: Dexin Zou, Shengjie Dong, Wei Du, Bing Sun and Xifa Wu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:312

    Content type: Research article

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  6. A recent genome-wide association study identified a susceptible locus in MIR4300HG gene that was associated with curve progression of adolescent idiopathic scoliosis (AIS) in the Japanese population. However, ...

    Authors: Yuwen Wang, Zhicheng Dai, Zhichong Wu, Zhenhua Feng, Zhen Liu, Xu Sun, Leilei Xu, Yong Qiu and Zezhang Zhu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:311

    Content type: Research article

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  7. In fracture-related infections (FRI), both the diagnosis of the infection and the identification of the causative pathogen are crucial to optimize treatment outcomes. Sonication has been successfully used for ...

    Authors: Petri Bellova, Veronika Knop-Hammad, Matthias Königshausen, Thomas A. Schildhauer, Jan Gessmann and Hinnerk Baecker

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:310

    Content type: Research article

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  8. The purpose of this study was to determine whether the gap-balancing technique with patient-specific instrumentation (PSI) and a new balancing device in total knee arthroplasty (TKA) can improve knee function ...

    Authors: Ting Deng, Tangyou Liu, Qing Lei, Lihong Cai and Song Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:309

    Content type: Research article

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  9. Robot-assisted platforms in spine surgery have rapidly developed into an attractive technology for both the surgeon and patient. Although current literature is promising, more clinical data is needed. The purp...

    Authors: Nathan J. Lee, Ian A. Buchanan, Venkat Boddapati, Justin Mathew, Gerard Marciano, Paul J. Park, Eric Leung, Avery L. Buchholz, John Pollina, Ehsan Jazini, Colin Haines, Thomas C. Schuler, Christopher R. Good, Joseph M. Lombardi and Ronald A. Lehman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:308

    Content type: Research article

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  10. Mounting evidence indicates that circular RNAs (circRNAs) participate in the occurrence and development of various diseases, including osteoarthritis (OA). However, the effects and molecular mechanism of circ_...

    Authors: Chao Liu, Ping Cheng, Jianjun Liang, Xiaoming Zhao and Wei Du

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:307

    Content type: Research article

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  11. The purpose of this study was to evaluate and compare the feasibility, safety, and efficacy of conventional open pedicle screw fixation (COPSF), percutaneous pedicle screw fixation (PPSF), and paraspinal poste...

    Authors: Chao Zhu, Bin Wang, Jian Yin and Xin Hui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:306

    Content type: Research article

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  12. Soft tissue balancing is essential for the success of total knee arthroplasty (TKA) and is mainly dependent on surgeon-defined assessment (SDA) or a gap-balancer (GB). However, an electronic sensor has been de...

    Authors: Ran Zhao, Yanqing Liu and Hua Tian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:305

    Content type: Research article

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  13. This systematic review was conducted to gather available evidence on the effectiveness of muscle pedicle bone flap transplantation in adult patients with femoral neck fractures.

    Authors: Yipeng Wu, Muguo Song, Guangliang Peng, Yongqing Xu, Yang Li, Mingjie Wei, Hui Tang, Qian Lv, Teng Wang and Xingbo Cai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:304

    Content type: Systematic review

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  14. Previous study showed that circular RNA Absent-Small-Homeotic-2--Like protein (circASH2L) was higher in rheumatoid arthritis (RA) patients. However, the roles and mechanisms of circASH2L in RA progression rema...

    Authors: Xia Li, Meiting Qu, Jie Zhang, Kuanyin Chen and Xianghui Ma

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:302

    Content type: Research article

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  15. Congenital pseudoarthrosis of the clavicle (CPC) is an uncommon entity. Owing to its scarce presentation, treatment of this disorder has not been well established. This study aimed (1) to compare surgical trea...

    Authors: Jin Li, Sheng Ping Tang, Hai Bo Mei, Jing Fan Shao, Bao Jie Shi, Hai Qiang Wang and Xin Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:301

    Content type: Research article

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  16. To analyze the effect of sacrificing the posterior cruciate ligament (PCL) on the early postoperative outcome of cruciate retaining (CR) highly congruent rotating platform TKA.

    Authors: Long Chen, Jie Xu, Yuan Lin, Fen Qi Luo and Yu Guo Yu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:299

    Content type: Research article

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  17. We aimed to evaluate reliability, radiological outcomes, and the impacts of anterior cervical hybrid construction on the adjacent segments for the multilevel cervical degenerative disc disease (mCDDD) and spon...

    Authors: Murat Yilmaz, Kemal Yucesoy, Resat S. Erbayraktar and Rıfat S. Altinag

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:298

    Content type: Research article

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  18. Angiotensin II (Ang II) is associated with rheumatoid arthritis (RA) development. The present study investigated the impact of Ang II on the expression of receptor activator of nuclear factor-κB ligand (RANKL)...

    Authors: Zhiping Zhao, Yongtao Zhang, Changyao Wang, Xiangyu Wang, Yingzhen Wang and Haining Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:297

    Content type: Research article

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  19. To explore the impact of different repair methods for a lateral meniscus posterior root tear on the biomechanics of the knee joint using finite element analysis.

    Authors: Jian-Yu Wang, Yan-Song Qi, Hu-Ri-Cha Bao, Yong-Sheng Xu, Bao-Gang Wei, Yong-Xiang Wang, Bing-Xian Ma, Hui-Wen Zhou and Fei Lv

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:296

    Content type: Research article

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  20. In tibial plateau fractures (TPF) the restoration of an anatomical joint surface as well as an exact subchondral screw position for postoperative stability is crucial for the outcome.

    Authors: F. Souleiman, R. Henkelmann, J. Theopold, J. Fakler, U. Spiegl and P. Hepp

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:295

    Content type: Research article

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  21. Osteosarcoma is a disease with high mortality in children and adolescents, and metastasis is one of the important clinical features of osteosarcoma. N6-Methyladenosine (m6A) is the most abundant methylation modif...

    Authors: Hua Liu, Guangzhen Qin, Yanan Ji, Xiaojian Wang, Hailin Bao, Xiaojun Guan, Aichun Wei and Zhigang Cai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:294

    Content type: Research article

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  22. Peritendinous adhesion is among the common complications after tendon injury. Numerous studies have been carried out to prevent its formation, including modifications of surgical procedures, postoperative care...

    Authors: Pengfei Li, Haiying Zhou, Tian Tu and Hui Lu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:293

    Content type: Research article

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  23. Culture-negative periprosthetic joint infections (PJIs) can complicate diagnosis and management of PJI. This study aimed to identify risk factors for culture-negative PJI and differences in clinical characteri...

    Authors: Shintaro Watanabe, Naomi Kobayashi, Akito Tomoyama, Hyonmin Choe, Etsuko Yamazaki and Yutaka Inaba

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:292

    Content type: Research article

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  24. Some unusual rotator cuff (RC) tears are located in more proximal tendinous portions, with substantial remnant tissue attached to the footprint. The two options for surgical repair are sacrificing or preservin...

    Authors: Hyung-Suk Choi, Byung-Ill Lee, Jae-Hyung Kim, Hyung-Ki Cho and Gi-Won Seo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:291

    Content type: Technical note

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  25. Osteoarthritis (OA) is a complex joint disease and chronic pain source, affecting a patient’s quality of life and posing a financial burden. As the dog is considered a nearly ideal species for translation rese...

    Authors: J. C. Alves, Ana Margarida Moniz Pereira dos Santos, Patrícia Jorge, Catarina Falcão Trigoso Vieira Branco Lavrador and L. Miguel Carreira

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:290

    Content type: Research article

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  26. Lateral tibial plateau fractures (TPFs) are often treated with conventional open reduction and internal fixation (ORIF) through standard anterolateral sub-meniscal arthrotomy. There has been increasing support...

    Authors: Xiangtian Deng, Hongzhi Hu, Yiran Zhang, Weijian Liu, Qingcheng Song, Xiaodong Cheng, Jian Zhu, Sifan Yang, Zhipeng Ye, Haitao Guan, Boyu Zhang, Zhanle Zheng and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:289

    Content type: Research article

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  27. The long pentraxin PTX3 is generating great interest given the recent discovery of its involvement in bone metabolism. This study investigates the role of circulating PTX3 as a marker of bone-related phenotype...

    Authors: Virginia Veronica Visconti, Chiara Greggi, Simona Fittipaldi, Donato Casamassima, Mariagrazia Tallarico, Francesco Romano, Annalisa Botta and Umberto Tarantino

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:288

    Content type: Research article

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    The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2021 16:331

  28. To describe a new technique for implanting a double-bundle titanium cable to treat acromioclavicular (AC) joint dislocation via the new guider, and evaluate clinic outcomes.

    Authors: Jun Wang, Yongfeng Cui, Yuhang Zhang and Hang Yin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:287

    Content type: Research article

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  29. This study is to describe the design and surgical techniques of three- dimensional-printed porous implants for proximal giant cell tumors of bone and evaluate the short-term clinical outcomes.

    Authors: Yuqi Zhang, Minxun Lu, Li Min, Jie Wang, Yitian Wang, Yi Luo, Yong Zhou, Hong Duan and Chongqi Tu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:286

    Content type: Research article

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  30. To investigate the clinical efficacy of locking compression plate fixation for the treatment of femoral intertrochanteric fractures in patients with preexisting proximal femoral deformity.

    Authors: Shan Fan, Mingming Yin, Yibo Xu, Cheng Ren, Teng Ma, Yao Lu, Ming Li, Zhong Li and Kun Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:285

    Content type: Research article

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  31. To evaluate the effect of postoperative BP treatment on improving the fusion rate after lumbar spinal fusion surgery by performing a meta-analysis of randomized controlled trials (RCTs) and other comparative c...

    Authors: Jun Mei, Xiaoxu Song, Xiaoming Guan, Dou Wu, Junjie Wang and Qiang Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:284

    Content type: Research article

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  32. Platelet-rich plasma (PRP) has been used to favor anterior cruciate ligament (ACL) healing after reconstruction surgeries. However, clinical data are still inconclusive and subjective about PRP. Thus, we propo...

    Authors: Allan Felipe Fattori Alves, José Ricardo de Arruda Miranda, Sérgio Augusto Santana de Souza, Ricardo Violante Pereira, Paulo Roberto de Almeida Silvares, Seizo Yamashita, Elenice Deffune and Diana Rodrigues de Pina

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:283

    Content type: Research article

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  33. Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of o...

    Authors: Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S. M. Xia, Y. L. Wang and Jack Chun-Yiu Cheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:282

    Content type: Research article

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  34. Nonunion is a rare complication for distal fibular fractures. However, when there is a high degree of comminution, nonunion may occur. In this article, we describe a novel technique that uses the oblong hole o...

    Authors: Young Uk Park, Sung Jae Kim and Hyong Nyun Kim

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:281

    Content type: Research article

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  35. The overarching goal of our research was to compare the clinical and radiological outcomes with different sizes of cages implantation in anterior cervical discectomy and fusion (ACDF), and to evaluate the effe...

    Authors: Changyan Wu, Xiaojuan Yang, Xu Gao, Liwei Shao, Fang Li, Yunxin Sun, Xiaoyu Liu, Shuaihao Yao and Yifu Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:280

    Content type: Research article

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  36. Curculigoside is a natural phenolic glycoside compound produced by Curculigo orchioides Gaertn. This study aimed to explore the effects of curculigoside in promoting the osteogenic differentiation of adipose-deri...

    Authors: Wei-Li You and Zheng-Long Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:279

    Content type: Research article

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  37. The association of the severity of clinical symptoms and level of functional performance with the degree of magnetic resonance imaging abnormalities in patients with lateral epicondylitis has not been fully el...

    Authors: Seok Woo Hong, Jeong-Hyun Kang, Jin Hun Park, Ji Na Kim, Hee Jin Park and Eugene Kim

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:278

    Content type: Research article

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  38. To explore the clinical efficacy of posterior LFF for cervical OPLL with radicular pain of upper limbs

    Authors: Bao Su, Jieliang Shen, Xiaoji Luo, Zhengxue Quan, Dianming Jiang, Xiaohua Peng and Ke Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:277

    Content type: Research article

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  39. Higher pedicle screw density posterior spinal fusion (PSF) constructs have not been shown to result in improved curve correction in Lenke 1 and 5 adolescent idiopathic scoliosis (AIS) but do increase cost. The...

    Authors: Timothy J. Skalak, Joel Gagnier, Michelle S. Caird, Frances A. Farley and Ying Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:276

    Content type: Research article

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  40. Hemophilic pseudotumor (HPT)-related fracture is a rare but severe complication in patients with HPTs. These fractures often occur in femurs. There is no consensus on the standard surgical protocol for HPT-rel...

    Authors: Keyu Chen, Guiyong Jiang, Yaowen Xu, Yunping Yang, Zexiong Mao, Jiaxin Lv, Fei Liu and Bin Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:275

    Content type: Research article

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  41. To develop and validate a nomogram useful in predicting recurrent lumbar disk herniation (rLDH) within 6 months after percutaneous endoscopic lumbar discectomy (PELD).

    Authors: Mengxian Jia, Yadong Sheng, Guoliang Chen, Wenbin Zhang, Jiajin Lin, Sheng Lu, Fayi Li, Jinwei Ying and Honglin Teng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:274

    Content type: Research article

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  42. The purpose of present study was to identify the differentially expressed genes (DEGs) associated with BMP-9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by using bioinformatics methods.

    Authors: Jia-qi Wu, Lin-bo Mao, Ling-feng Liu, Yong-mei Li, Jian Wu, Jiao Yao, Feng-huan Zhang, Ting-yu Liu and Ling Yuan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:273

    Content type: Research article

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  43. The purpose of the current study was to explore the role and underlying mechanism of cellular retinoic acid binding protein 2 (CRABP2) in dexamethasone (DEX)-induced apoptosis in human osteoblast cells.

    Authors: Haiping Zhang, Ziliang Yu, Farui Sun and Jin Jin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:272

    Content type: Research article

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  44. Posterior hemivertebra resection and short-segment fusion with pedicle screws are an established treatment in congenital scoliosis, which require pediatric-specific instrumentation. The purpose of this study w...

    Authors: Mohammad Zarei, Ehsan Ghadimi, Nima Bagheri, Seyed Mir Mansour Moazen Jamshidi, Alireza Moharrami, Mersad Moosavi and Soroush Baghdadi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:271

    Content type: Research article

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  45. Implant-associated infections depict a major challenge in orthopedics and trauma surgery putting a high burden on the patients and health care systems, strongly requiring improvement of infection prevention an...

    Authors: Nike Walter, Daniel Popp, Viola Freigang, Michael Nerlich, Volker Alt and Markus Rupp

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:270

    Content type: Research article

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  46. Sacral insufficiency fracture (SIF) is rarer than osteoporotic vertebral compression fracture that occurs at other levels of the thoracolumbar spine. Percutaneous sacroplasty can effectively relieve pain and i...

    Authors: Feng-Chen Kao, Yao-Chun Hsu, Tzu-Shan Chen, Pao-Hsin Liu and Yuan-Kun Tu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:269

    Content type: Research article

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  47. To analyze and compare the effects of peri-treatment analgesics on acute and chronic pain and postoperative functional recovery of patients with thoracolumbar fractures, so as to guide the clinical drug use.

    Authors: Hao Yuan, Quan-Yuan Chang, Jie Chen, Ya-Ting Wang, Zong-Jin Gan, Song Wen, Ting-Ting Li and Liu-Lin Xiong

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:268

    Content type: Research article

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