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  1. Adult developmental dysplasia of the hip is an untreated congenital hip dysplasia that results in adult hip pain. One of the usual and effective methods for the treatment of this condition is periacetabular os...

    Authors: Rui Luo, Guomin Li, Bo Li, Ruyin Hu and Yankun Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:157

    Content type: Research article

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  2. Accurate preoperative planning is an important step for accurate reconstruction in total hip arthroplasty (THA). Presently, preoperative planning is completed using either a two-dimensional (2D) template or th...

    Authors: Jiabang Huo, Guangxin Huang, Dong Han, Xinjie Wang, Yufan Bu, Ya Chen, Daozhang Cai and Chang Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:156

    Content type: Research article

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  3. On the 11th March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Multiple new guidelines were proposed and existing models of social, domestic and hospital care altered. Most he...

    Authors: Alice Wignall, Vasileios Giannoudis, Chiranjit De, Andrea Jimenez, Simon Sturdee, Sohail Nisar, Hemant Pandit, Aashish Gulati and Jeya Palan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:155

    Content type: Research article

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  4. The coronavirus disease 2019 (COVID-19) pandemic has led to dramatic disruptions to orthopedic services. The purpose of this study is to quantify the reinstatement of elective orthopedic surgeries of our insti...

    Authors: Teng-fei Lou, Zun Ren, Zheng-hua Sun, Wei Wang and Cun-yi Fan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:154

    Content type: Research article

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  5. This study aims to analyze the clinical outcome of a new ultrasound-guided surgery for partial plantar fasciotomy performed with a needle for treatment of plantar fasciitis.

    Authors: A. Iborra, M. Villanueva, P. Sanz-Ruiz, Antonio Martin and Concepción Noriega

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:153

    Content type: Research article

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  6. Elderly patients with femoral neck fractures are at a higher risk of dislocation after hip arthroplasty procedures. In comparison with total hip arthroplasty (THA), bipolar hemiarthroplasty (HA) and dual-mobil...

    Authors: Hsuan-Hsiao Ma, Te-Feng Arthur Chou, Fu-Yuan Pai, Shang-Wen Tsai, Cheng-Fong Chen, Po-Kuei Wu and Wei-Ming Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:152

    Content type: Research article

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  7. Spina bifida occulta (SBO) is one of the most common congenital spinal deformities. Although many studies have demonstrated the influence of lumbosacral dysplasia on low back pain (LBP) in young athletes, ther...

    Authors: Wenhao Li, Zhencheng Xiong, Chunke Dong, Jipeng Song, Liubo Zhang, Jun Zhou, Yanlei Wang, Ping Yi, Feng Yang, Xiangsheng Tang and Mingsheng Tan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:151

    Content type: Research article

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  8. We aimed to investigate the therapeutic effects of Moringa oleifera leaf extracts on osteogenic induction of rat bone marrow mesenchymal stem cells (BMSCs) following peroxidative damage and to explore the underly...

    Authors: Meiling Liu, Haifeng Ding, Hongzhi Wang, Manfeng Wang, Xiaowei Wu, Lu Gan, Luyang Cheng and Xianglu Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:150

    Content type: Research article

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  9. Knee osteoarthritis associated with extra-articular deformity (EAD) can confront the arthroplasty surgeons with challenges of bone resection and soft tissue balancing. The aim of this study was to describe a s...

    Authors: Jing-yang Sun, Guo-qiang Zhang, Jun-min Shen, Yin-qiao Du, Tie-jian Li, Zong-jie Geng, Yong-gang Zhou and Yan Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:149

    Content type: Research article

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  10. Popliteomeniscal fascicles (PMF) are considered the posterolateral meniscocapsular extensions which connect the lateral meniscus to the edge of the tibia. PMFs disruption leads to hypermobility of the lateral ...

    Authors: Alessio D’Addona, Andrea Izzo, Giovanni Di Vico, Donato Rosa and Nicola Maffulli

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:148

    Content type: Systematic review

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  11. Silymarin (SMN), a polyphenolic flavonoid, is involved in multiple bioactive functions including anti-inflammation. Pretreatment with SMN demonstrated chondroprotection against tumour necrosis factor-alpha (TN...

    Authors: Wen-Tien Wu, Yi-Ru Chen, Dai-Hua Lu, Fedor Svyatoslavovich Senatov, Kai-Chiang Yang and Chen-Chie Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:147

    Content type: Research article

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  12. A great deal of evidence has supported that growth differentiation factor 5 (GDF5) is associated with the occurrence of knee osteoarthritis (KOA), while their results are not consistent. In the present study, ...

    Authors: Bin Jia, Yaping Jiang, Yingxing Xu, Yingzhen Wang and Tao Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:146

    Content type: Systematic review

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  13. Muscle strength around the hip after total hip arthroplasty (THA) is crucial for preventing dislocation and limping. This study aimed to assess and compare muscle volume and degeneration after THA using the po...

    Authors: Taku Ukai, Goro Ebihara, Haruka Omura and Masahiko Watanabe

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:145

    Content type: Research article

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  14. The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL...

    Authors: Hai Wang, Leilei Qin, Jiawei Wang and Wei Huang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:144

    Content type: Research article

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  15. Osteoarthritis (OA) is the most common joint disorder in the USA, and knee OA has the highest prevalence. Inflammation and decrease in vascularization are key factors in the degeneration of articular cartilage...

    Authors: Ashim Gupta, Nicola Maffulli, Hugo C. Rodriguez, Cassidy E. Lee, Howard J. Levy and Saadiq F. El-Amin III

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:143

    Content type: Study protocol

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  16. Leg length inequalities (LLI) are a common condition that can be associated with detrimental effects like low back pain and osteoarthritis. Inertial measurement units (IMUs) offer the chance to analyze daily a...

    Authors: Hannah Lena Siebers, Jörg Eschweiler, Valentin M. Quack, Markus Tingart and Marcel Betsch

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:142

    Content type: Research article

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  17. Half of osteonecrosis of the femoral head (ONFH) patients suffer femoral head collapse at initial diagnosis, and more than half are bilaterally affected. This study developed a percutaneous autologous impactio...

    Authors: Yutaka Kuroda, Manabu Nankaku, Yaichiro Okuzu, Toshiyuki Kawai, Koji Goto and Shuichi Matsuda

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:141

    Content type: Research article

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  18. To clarify contemporary indications for first-time revision surgery after primary cementless total hip arthroplasty (THA) for addressing potential issues with cementless THA.

    Authors: Goro Motomura, Satoshi Hamai, Satoshi Ikemura, Masanori Fujii, Shinya Kawahara, Soichiro Yoshino and Yasuharu Nakashima

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:140

    Content type: Research article

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  19. To investigate osteointegration at the graft-bone interface and the prevention of osteoarthritis after anterior cruciate ligament (ACL) reconstruction using a silk-collagen scaffold with both ends modified by ...

    Authors: Fanggang Bi, Yangdi Chen, Junqi Liu, Yafei Wang, Danfeng Xu and Ke Tian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:139

    Content type: Research article

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  20. Biomechanical comparison of wedge and biconcave deformity of different height restoration after augmentation of osteoporotic vertebral compression fractures was analyzed by three-dimensional finite element ana...

    Authors: Xiao-Hua Zuo, Yin-Bing Chen, Peng Xie, Wen-Dong Zhang, Xiang-Yun Xue, Qian-Xi Zhang, Ben Shan, Xiao-Bing Zhang, Hong-Guang Bao and Yan-Na Si

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:138

    Content type: Research article

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  21. Periprosthetic infection is a major cause of failure after segmental endoprosthetic reconstruction. The purpose of this study is to determine whether certain aspects of drain output affect infection risk, part...

    Authors: Jiayong Liu, Zhengfu Fan, Marc El Beaino, Valerae O. Lewis, Bryan S. Moon, Robert L. Satcher, Justin E. Bird, Spencer J. Frink and Patrick P. Lin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:137

    Content type: Research article

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  22. The Wnt planar cell polarity (PCP) pathway is implicated in osteoarthritis (OA) both in animals and in humans. Van Gogh-like 2 (Vangl2) is a key PCP protein that is required for the orientation and alignment o...

    Authors: Ke Zhang, Zhuoying Li, Yunyang Lu, Linyi Xiang, Jiadong Sun and Hong Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:136

    Content type: Research article

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  23. To evaluates the efficacy and safety of rivaroxaban versus aspirin in prevention of venous thromboembolism (VTE) following total hip (THA) or knee arthroplasty (TKA) or hip fracture surgery.

    Authors: Bangsheng Hu, Lianxiang Jiang, Haixia Tang, Meizhu Hu, Jun Yu and Zeping Dai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:135

    Content type: Systematic review

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  24. The aim of this study is to investigate the prognostic value of tibial component coverage (over-hang and under-hang) and the alignment of total knee arthroplasty (TKA) components 1 week after surgery. We selec...

    Authors: Changquan Liu, Guanglei Zhao, Kangming Chen, Jinyang Lyu, Jie Chen, Jingsheng Shi, Gangyong Huang, Feiyan Chen, Yibing Wei, Siqun Wang and Jun Xia

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:134

    Content type: Research article

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  25. Osteoarthritis (OA) is thought to be the most prevalent chronic joint disease, especially in Tibet of China. Here, we aimed to explore the integrative lncRNA and mRNA landscape between the OA patients of Tibet...

    Authors: Junming Luo, Xiaoqin Luo, Zhili Duan, Wenbin Bai, Xiaoming Che, Zhongshu Shan, Xiaona Li and Jinwu Peng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:133

    Content type: Research article

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  26. Osteoarthritis (OA) is a kind of systemic musculoskeletal disorder and a most important factor for causing disability and physical painfulness. Nevertheless, due to the fact that OA can be triggered by multipl...

    Authors: Chao Li, Li Li and Tian Lan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:132

    Content type: Research article

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  27. Three-dimensional preoperative planning was applied for the osteosynthesis of distal radius fractures. The objective of this study was to evaluate the reproducibility of three-dimensional preoperative planning...

    Authors: Yuichi Yoshii, Takeshi Ogawa, Atsuo Shigi, Kunihiro Oka, Tsuyoshi Murase and Tomoo Ishii

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:131

    Content type: Research article

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  28. Although integrated traditional Chinese medicine (TCM) has long been indicated to be effective in the treatment of sciatica and is widely used in the management of this condition, the mechanism by which integr...

    Authors: Yi Wang, Guogang Dai, Yan Xu, Ling Jiang, Zhibin Fu, Jiao Xia, Guogang Tian and Wanli Du

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:130

    Content type: Research article

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  29. Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate...

    Authors: Minghui Sun, Weijun Wang, Lingtian Min, Cheng Chen, Qing Li and Wenjie Weng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:129

    Content type: Research article

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  30. Whether vastus medialis obliquus atrophy exists in patients with patellofemoral pain syndrome and whether the amount of atrophy differs between the vastus medialis obliquus and vastus lateralis muscles remain ...

    Authors: Conglei Dong, Ming Li, Kuo Hao, Chao Zhao, Kang Piao, Wei Lin, Chongyi Fan, Yingzhen Niu and Wang Fei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:128

    Content type: Research article

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  31. With the fourth largest metropolitan population density, motor vehicle drivers in Adelaide, South Australia, record the most number of motor vehicle insurance claims in Australia. Previous studies have shown a...

    Authors: John M. Abrahams, Christopher Sagar and Mark Rickman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:127

    Content type: Research article

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  32. This study was conducted with the aim to compare the effect of posterior condyle offset (PCO) changes on knee joint function of patients following total knee replacement (TKR).

    Authors: Yimin Zhang, Jun Wang, Miao Zhang and Yun Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:126

    Content type: Research article

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  33. Recently, a standardized uptake value (SUV) has been used to evaluate bone single-photon emission computed tomography (SPECT). The aim of this study was to investigate quantitative SPECT imaging of uninfected ...

    Authors: Keisuke Oe, Feibi Zeng, Tomoaki Fukui, Munenobu Nogami, Takamichi Murakami, Tomoyuki Matsumoto, Ryosuke Kuroda and Takahiro Niikura

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:125

    Content type: Research article

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  34. Osteoarthritis (OA) is a multiple factorial disease with unidentified specific markers. The alternate method such as biochemical and genetic markers for the diagnosis of osteoarthritis is an undeniable need of...

    Authors: Yasmin Badshah, Maria Shabbir, Hunza Hayat, Zoha Fatima, Asad Burki, Sidra Khan and Shafiq ur Rehman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:124

    Content type: Research article

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  35. To investigate the efficacy and safety of allograft and hydroxyapatite (HA) as substitutes for autograft in anterior cervical discectomy and fusion (ACDF).

    Authors: Changsheng Yang, Wentao Zhuo, Qingchu Li, Caiqiang Huang, Huibo Yan and Dadi Jin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:123

    Content type: Research article

    Published on:

  36. Pelvic bone fractures are one of the biggest challenges faced by trauma surgeons. Especially, the presence of bleeding and hemodynamic instability features is associated with high morbidity and mortality in pa...

    Authors: Myoung Jun Kim, Jae Gil Lee, Eun Hwa Kim and Seung Hwan Lee

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:122

    Content type: Research article

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  37. Although efficacy is related to many factors, the surgical approach is one of the most important intervention factors for complex ankle fractures. Ankle fractures involving the distal tibial plafond frequently...

    Authors: Tong Liu, Yiheng Cheng and Wenqing Qu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:120

    Content type: Research article

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  38. Although researchers have adopted various methods for the resection and reconstruction of periacetabular tumors, the total incidence rate of complications remains high. Aiming for preserving the acetabulum and...

    Authors: Chunzhi Yi, Jiaqian Zheng, Ruoyu Li, Yun Lan, Mincong He, Jieqing Lai, Tianan Guan, Fengxiang Pang, Zongquan Mo, Peng Chen, Yue Li, Nannan Zhou, Xingfu Yang and Bin Fang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:119

    Content type: Research article

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  39. This study was performed to investigate the change in the bony alignment of the foot after tendo-Achilles lengthening (TAL) and the factors that affect these changes in patients with planovalgus foot deformity.

    Authors: Nak Tscheol Kim, Young Tae Lee, Moon Seok Park, Kyoung Min Lee, Oh Sang Kwon and Ki Hyuk Sung

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:118

    Content type: Research article

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  40. Despite tibial plateau fractures are often associated with meniscal tears, the association between meniscal tears and Schatzker classification remains unclear. The purpose of this study was to assess the frequ...

    Authors: Xiangtian Deng, Hongzhi Hu, Yuchuan Wang, Decheng Shao and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:117

    Content type: Research article

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  41. Long non-coding RNA heart and neural crest derivatives expressed 2-antisense RNA 1 (HAND2-AS1) was found to be elevated in rheumatoid arthritis (RA) fibroblast-like synoviocytes (RA-FLSs). However, whether HAN...

    Authors: Yuhua Su, Yajing Liu, Chao Ma, Chunxiao Guan, Xiufen Ma and Shan Meng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:116

    Content type: Research article

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  42. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Sujin Kang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:115

    Content type: Correction

    Published on:

    The original article was published in Journal of Orthopaedic Surgery and Research 2021 16:18

  43. There is still lack of data on deep vein thrombosis (DVT) following bone trauma. This study aimed to determine the epidemiologic characteristics of deep venous thrombosis (DVT) of lower extremities following tibi...

    Authors: Yanbin Zhu, Wei Chen, Junyong Li, Kuo Zhao, Junzhe Zhang, Hongyu Meng, Yingze Zhang and Qi Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:113

    Content type: Research article

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  44. Treatment of early-onset scoliosis (EOS) is still a challenge to patients, families, and surgeons. Previous studies have indicated that EOS patients are at high risk for complications following growth-friendly...

    Authors: Mohammad Zarei, Mehdi Tavakoli, Ehsan Ghadimi, Alireza Moharrami, Ali Nili, Ali Vafaei, Seyed Saeed Tamehri Zadeh and Soroush Baghdadi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:112

    Content type: Research article

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  45. We aimed to evaluate the safety and efficacy of intra-articular (IA) magnesium (Mg) for postoperative pain relief after arthroscopic knee surgery.

    Authors: Lijun Shi, Haiyun Zhu, Jinhui Ma, Li-Li Shi, Fuqiang Gao and Wei Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:111

    Content type: Research article

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  46. Parallel osteotomy is essential for favorable osteotomy reduction and healing and technically challenging during diaphyseal ulnar shortening osteotomy (USO). This study aimed to evaluate the advantages of guid...

    Authors: Jong Woo Kang, Soo Min Cha, Sang-gyun Kim, In Cheul Choi, Dong Hun Suh and Jong Woong Park

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:110

    Content type: Research article

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  47. Osteonecrosis of the femoral head (ONFH) is a disabling disease, which often involves young patients. Recently, various hip-preserving surgeries were recommended to delay total hip arthroplasty (THA).

    Authors: Ke Jie, Wenjun Feng, Feilong Li, Keliang Wu, Jinlun Chen, Guanming Zhou, Huiliang Zeng and Yirong Zeng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:109

    Content type: Research article

    Published on:

  48. This study aimed to determine the effects of denosumab treatment on the joint destruction of Japanese females with rheumatoid arthritis (RA) and anti-cyclic citrullinated peptide (CCP) antibodies.

    Authors: Yu Mori, Takuya Izumiyama, Hiroaki Kurishima, Masayuki Kamimura, Kazuyoshi Baba, Naoko Mori and Eiji Itoi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:107

    Content type: Research article

    Published on:

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