Articles

Radiographic analysis of specific morphometrics and patient-reported outcomes (PROMIS) for surgical repair of zones 2 and 3 fifth metatarsal fractures

Zones 2 and 3 fifth metatarsal fractures are often treated with intramedullary fixation due to an increased risk of nonunion. A previous 3-dimensional (3D) computerized tomography (CT) imaging study by our gro...

Authors: Rusheel Nayak, Joshua Barrett, Milap S. Patel, Mauricio P. Barbosa and Anish R. Kadakia

Deer antler extract potentially facilitates xiphoid cartilage growth and regeneration and prevents inflammatory susceptibility by regulating multiple functional genes

Deer antler is a zoological exception due to its fantastic characteristics, including amazing growth rate and repeatable regeneration. Deer antler has been used as a key ingredient in traditional Chinese medic...

Authors: Mengqi Guan, Daian Pan, Mei Zhang, Xiangyang Leng and Baojin Yao

Systematic review of intervertebral disc repair: a bibliometric analysis of the 100 most-cited articles

A bibliometric review of the literature.

Authors: Gang Xu, Xianglong Meng, Juan Guan, Yaozhong Xing, Zihe Feng and Yong Hai

Application of modified closed biopsy in rabbit model of VX2-transplanted bone tumor

This study was aimed to explore the application value of modified closed biopsy technique in puncture biopsy of rabbit VX2 transplanted bone tumor model.

Authors: Lei Peng Bai, Jia Xing Lv, Ling Wei Kong, Hai Ying Cao and Yu Jin

C-Nail versus plate osteosynthesis in displaced intra-articular calcaneal fractures—a comparative retrospective study

Locking plate osteosynthesis via an L-shaped lateral approach is the gold standard in treating displaced intra-articular calcaneal fractures. High complication rates are known for this approach. The most frequ...

Authors: Eva Steinhausen, Wolfgang Martin, Rolf Lefering, Sven Lundin, Martin Glombitza, Bastian Mester, Nikolaus Brinkmann and Marcel Dudda

The effect of the platelet-rich plasma and ozone therapy on tendon-to-bone healing in the rabbit rotator cuff repair model

The aim of this study is to histologically and biomechanically investigate the effects of local PRP and ozone therapy (O₂O₃) on tendon-to-bone healing in a rabbit model of the supraspinatus tendon tear.

Authors: Murat Gurger, Gokhan Once, Erhan Yilmaz, Sukru Demir, Ilknur Calik, Yakup Say, Ahmet Kavakli, Sefa Key, Mustafa Umit Gurbuz and Onur Bingollu

Hip pathologies in mucopolysaccharidosis type III

Mucopolysaccharidosis type III (MPS III) comprises a group of rare lysosomal storage diseases. Although musculoskeletal symptoms are less pronounced than in other MPS subtypes, pathologies of hip and spine hav...

Authors: Sandra Rafaela Breyer, Eik Vettorazzi, Leonie Schmitz, Amit Gulati, Katharina Maria von Cossel, Alexander Spiro, Martin Rupprecht, Ralf Stuecker and Nicole Maria Muschol

Correction to: Efficacy of additional corticosteroids to multimodal cocktail periarticular injection in total knee arthroplasty: a meta-analysis of randomized controlled trials

An amendment to this paper has been published and can be accessed via the original article.

Authors: Qi Li, Guo Mu, Xiangbo Liu and Milian Chen

Low post-arthroplasty infection rate is possible in developing countries: long-term experience of local vancomycin use in Iran

Utilizing intrawound vancomycin powder in TKA surgery has yielded rather contrasting results in the current literature. Furthermore, CDC criteria, although effective in general, are not specifically designed f...

Authors: Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Fardis Vosoughi, Mohamad Tahami, Majid Khalilizad and Hamid Rabie

The impact of tourniquet on tibial bone cement penetration in different zones in primary total knee arthroplasty: a meta-analysis

Cement mantle penetration and the cement–bone interface strength were critical to a successful primary total knee arthroplasty (TKA). It remained unclear whether decreased blood and fat in the cancellous bone ...

Authors: Changjiao Sun, Xin Yang, Xiaofei Zhang, Qi Ma, Peng Yu, Xu Cai and Yonggang Zhou

Anterolateral approach with two incisions versus posterior median approach in the treatment of middle- and distal-third humeral shaft fractures

The surgical approaches remain controversial for the treatment of middle and distal-third humeral shaft (MDTHS) fractures. This study compared clinical effects of the anterolateral approach with two incisions ...

Authors: Qiang Huang, Yao Lu, Zhi Meng Wang, Liang Sun, Teng Ma, Qian Wang, Ming Li, Hong Liang Liu, Ming Ming Hou, Han Zhong Xue, Kun Zhang and Zhong Li

Duration of immobilisation after Achilles tendon rupture repair by open surgery: a retrospective cohort study

The best treatment for acute Achilles tendon ruptures remains controversial. No cohort studies have compared different immobilisation durations after open surgery. This retrospective cohort study aimed to dete...

Authors: Xiang Yu Xu, Shan Gao, Yang Lv, Fang Zhou, Chen Jiao, Ji Xing Fan and Teng Jiao Zhu

The use of bone turnover markers for monitoring the treatment of osteoporosis in postmenopausal females undergoing total knee arthroplasty: a prospective randomized study

Osteoporosis (OP) and osteoarthritis (OA) commonly coexist in postmenopausal females. The decrease in bone density and increase in bone resorption in postmenopausal females with OP may consequently affect the ...

Authors: Rui Ma, Mengjun Wu, Yongwei Li, Jialin Wang, Pei Yang, Yuanyuan Chen, Wei Wang, Jinhui Song and Kunzheng Wang

Assessment of spino cranial angle of cervical spine sagittal balance system after multi-level anterior cervical discectomy and fusion

To analyze the impact of spino cranial angle (SCA) on alteration of cervical alignment after multi-level anterior cervical discectomy fusion (ACDF) and explore the relationship between SCA and health-related q...

Authors: Zheng Wang, Zhi-Wei Wang, Xi-Wen Fan, Xian-Da Gao, Wen-Yuan Ding and Da-Long Yang

Effects of lower limb and pelvic pin positions on leg length and offset measurement errors in experimental total hip arthroplasty

Leg length (LL) and offset (OS) are important factors in total hip arthroplasty (THA). Because most LL and OS callipers used in THA depend on fixed points on the pelvis and the femur, limb position could affec...

Authors: Haruo Kawamura, Yasuhiko Watanabe, Tomofumi Nishino and Hajime Mishima

Characteristics of three-dimensional acetabular morphology of patients with excellent outcome after rotational acetabular osteotomy over 20 years

Rotational acetabular osteotomy (RAO) is a type of pelvic osteotomy performed to improve the acetabular bony coverage against the femoral head for patients with acetabular dysplasia. The acetabular bony covera...

Authors: Takeyuki Tanaka, Toru Moro, Hisatoshi Ishikura, Kazuaki Hashikura, Taizo Kaneko and Sakae Tanaka

Finite element analysis of different locking plate fixation methods for the treatment of ulnar head fracture

Ulnar head fractures are increasingly higher with the growing proportion of the elderly people. Failure to achieve a stable anatomic reduction of ulna head fracture may lead to a distal radioulnar joint (DRUJ)...

Authors: Yue Zhang, Qin Shao, Chensong Yang, Changqing Ai, Di Zhou, Yang Yu and Guixin Sun

Correlation of osteoarthritis or rheumatoid arthritis with bone mineral density in adults aged 20–59 years

It is reported that osteoporosis commonly occurs among patients with rheumatoid arthritis (RA), whereas the association between osteoporosis and osteoarthritis (OA) remains controversial. Our aim in this study...

Authors: Zhongxin Zhu, Gangfeng Hu, Fang Jin and Xiaocong Yao

Machine learning analysis of gene expression profile reveals a novel diagnostic signature for osteoporosis

Osteoporosis (OP) is increasingly prevalent with the aging of the world population. It is urgent to identify efficient diagnostic signatures for the clinical application.

Authors: Xinlei Chen, Guangping Liu, Shuxiang Wang, Haiyang Zhang and Peng Xue

Advantages of patient-specific cutting guides with disposable instrumentation in total knee arthroplasty: a case control study

Total knee arthroplasty (TKA) is most frequently planned using conventional two-dimensional weight-bearing lower limb radiographs and is performed with conventional femoral and tibial cutting guides. Questions...

Authors: Kevin Moerenhout, Behrang Allami, Georgios Gkagkalis, Olivier Guyen and Brigitte M. Jolles

Re-operation rate after surgical treatment of osteochondral lesions of the talus in paediatric and adolescent patients

The aim of this study is to analyse the re-operation rate after surgical treatment of osteochondral lesions of the talus (OCLTs) in children and adolescents.

Authors: Daniel Körner, Christoph E. Gonser, Stefan Döbele, Christian Konrads, Fabian Springer and Gabriel Keller

Clinical outcomes after mini-hook plate fixation for small avulsion fractures around the interphalangeal or metacarpophalangeal joints of the hand

Mini-hook plate has been described for the treatment of various small avulsion fragments in the hand. This retrospective study aimed to evaluate clinical outcomes after mini-hook plate fixation in patients wit...

Authors: Jung Il Lee, Ki-Chul Park, Hyun Soo So and Duk Hee Lee

Patella resurfacing during total knee arthroplasty is cost-effective and has lower re-operation rates compared to non-resurfacing

The decision to resurface the patella as part of total knee arthroplasty may be influenced by the surgeon’s preference, education, training, tradition and geographic location. Advocates for non-resurfacing or ...

Authors: Thomas Parsons, Talal Al-Jabri, Nick D. Clement, Nicola Maffulli and Deiary F. Kader

Guided growth in the correction of knee deformity in patients with congenital insensitivity to pain

Orthopedic manifestations of congenital insensitivity to pain (CIP) can be devastating if left untreated. Knee deformities are common in patients with CIP and might lead to joint destruction and loss of walkin...

Authors: Soroush Baghdadi, Sadegh Saberi and Taghi Baghdadi

Risk factors of postoperative bone cement leakage on osteoporotic vertebral compression fracture: a retrospective study

To investigate risk factors of bone cement leakage in percutaneous vertebroplasty(PVP)for osteoporotic vertebral compression fracture (OVCF).

Authors: Kui Zhang, Jiang She, Yandong Zhu, Wenji Wang, Erliang Li and Ding Ma

Effect of childhood overweight on distal metaphyseal radius fractures treated by closed reduction

The medical community has recognized overweight as an epidemic negatively affecting a large proportion of the pediatric population, but few studies have been performed to investigate the relationship between o...

Authors: Yu Liu, Chunjie Liu, Dongmei Guo, Ning Wang, Ying Zhao and Dan Li

Retraction Note: Effect of sagittal femoral component alignment on biomechanics after mobile-bearing total knee arthroplasty

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13018-019-1458-5.

Authors: Yong-Gon Koh, Jin-Ah Lee, Hwa-Yong Lee, Dong-Suk Suh, Hyo-Jeong Kim and Kyoung-Tak Kang

To explore the reasonable selection of clavicular hook plate to reduce the occurrence of subacromial impingement syndrome after operation

Acromioclavicular joint dislocation is a shoulder joint injury common in the clinical setting and is generally surgically treated with clavicular hook plate technique with confirmed curative effect. However, s...

Authors: Rui Qiao, Jiarui Yang, Kun Zhang and Zhe Song

Patella fractures treated with suture tension band fixation

Patella fractures requiring surgery are traditionally treated using metallic implants, which are associated with high re-operation rates, mainly due to implant prominence. To overcome the problem of prominent ...

Authors: J. Adjal and I. Ban

The most appropriate titanium mesh cage size for anterior spinal reconstruction after single-level lumbar total en bloc spondylectomy: a finite element analysis and cadaveric validation study

There is little information available regarding the cage diameter that can provide the most rigid construct reconstruction after total en bloc spondylectomy (TES). The aim of this study was thus to determine t...

Authors: Permsak Paholpak, Winai Sirichativapee, Taweechok Wisanuyotin, Weerachai Kosuwon, Yuichi Kasai and Hideki Murakami

Implant design affects walking and stair navigation after total knee arthroplasty: a double-blinded randomised controlled trial

Dissimilar total knee arthroplasty implant designs offer different functional characteristics. This is the first work in the literature to fully assess the Columbus ultra-congruent mobile (UCR) system with a r...

Authors: Dimitrios-Sokratis Komaris, Cheral Govind, Andrew James Murphy, Jon Clarke, Alistair Ewen, Hollie Leonard and Philip Riches

A comprehensive comparison between cementless and cemented fixation in the total knee arthroplasty: an updated systematic review and meta-analysis

Whether the cement should be used in the total knee arthroplasty (TKA) was still in controversy. This meta-analysis was performed to compare the efficacy of two kinds of fixation.

Authors: Yuan Liu, Yi Zeng, Yuangang Wu, Mingyang Li, Huiqi Xie and Bin Shen

Survivorship and prognostic factors for pleomorphic liposarcoma: a population-based study

Pleomorphic liposarcoma is the least common but most aggressive subtype of liposarcoma. Very few studies have presented data on pleomorphic liposarcoma specifically, often including a limited number of cases a...

Authors: Lu Wan, Chao Tu, Lin Qi and Zhihong Li

Depicting developing trend and core knowledge of hip fracture research: a bibliometric and visualised analysis

Hip fracture is common and carries high morbidity and mortality; thus, it has become a vital concern. We aim to analyse the present status, worldwide trends in hip fracture and state of clinical research.

Authors: Guanrong Peng, Zhenhua Guan, Yunfei Hou, Jiaxiang Gao, Wenqun Rao, Xianyun Yuan, Jiusheng Guo, Xiaohua Huang, Zhangrong Zhong and Jianhao Lin

TKR after posttraumatic and primary knee osteoarthritis: a comparative study

A few literatures reported that the outcomes of total knee replacement (TKR) in posttraumatic osteoarthritis (PTOA) were lower compared to TKR in primary osteoarthritis (primary OA). The study’s purpose was to...

Authors: Ong-art Phruetthiphat, Biagio Zampogna, Sebastiano Vasta, Benyapa Tassanawipas, Yubo Gao and John J. Callaghan

Hemiarthroplasty compared to total hip arthroplasty for the treatment of femoral neck fractures: a systematic review and meta-analysis

Hip replacement is divided into total hip arthroplasty (THA) and hemiarthroplasty (HA); it is still controversial whether to choose THA or HA for femoral neck fractures (FNF). The goal of this study was to rev...

Authors: Xinbo Li and Jianning Luo

The effect of the WKYMVm peptide on promoting mBMSC secretion of exosomes to induce M2 macrophage polarization through the FPR2 pathway

When multicystic vesicles (precursors of exosomes) are formed in cells, there are two results. One is decomposition by lysosomes, and the other is the generation of exosomes that are transported out through th...

Authors: Wenbo Zhao, Junxian Hu and Qingyi He

Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis

The dysregulation of circular RNAs (circRNAs) has been identified in various human diseases, including osteoarthritis (OA). The purpose of this study was to identify the role and mechanism of circ_SLC39A8 in r...

Authors: Jizhe Yu, Yushuang Qin and Naxin Zhou

Comparison of the inner side and two-sided approaches for iliac crest bone graft harvesting for pediatric pelvic osteotomy

The iliac crest is one of the most used bone graft sources. In this study, we aimed to identify the effects of inner side and two-sided approaches for iliac crest bone harvesting on post-surgery ilium growth i...

Authors: Xin Chen, Kai Chen and Yuxi Su

Application of a double reverse traction repositor in the retrograde intramedullary nailing of distal femur fractures

The purpose of this prospective study was to introduce the application of a double reverse traction repositor (DRTR) in the retrograde intramedullary nailing (RE-IMN) of AO/OTA 33A distal femur fractures.

Authors: Xiaodong Lian, Kuo Zhao, Wei Chen, Junzhe Zhang, Junyong Li, Hongyu Meng, Zhiyong Hou and Yingze Zhang

Letter to the Editors regarding the article “Patellar resurfacing in primary total knee arthroplasty: a meta-analysis of randomized controlled trials”

Authors: Zhong-min Fu, Xiu-mei Tang, Duan Wang, Ning Ning and Zong-ke Zhou

Microendoscopy-assisted extraforaminal lumbar interbody fusion for treating single-level spondylodesis

Lumbar interbody fusion is a standard technique for treating degenerative lumbar disorders involving instability. Due to its invasiveness, a minimally invasive technique, extraforaminal lumbar interbody fusion...

Authors: Motohide Shibayama, Guang Hua Li, Li Guo Zhu, Zenya Ito and Fujio Ito

Circ-AFF2/miR-650/CNP axis promotes proliferation, inflammatory response, migration, and invasion of rheumatoid arthritis synovial fibroblasts

Circular RNAs (circRNAs) are associated with rheumatoid arthritis (RA) development. The purpose of this study is to explore the function and mechanism of circRNA fragile mental retardation 2 (circ-AFF2) in the...

Authors: Wei Qu, Ling Jiang and Guanhua Hou

Application of WALANT technique for repairing finger skin defect with a random skin flap

Wide-awake local anesthesia no tourniquet (WALANT) technique has emerged among hand surgeons with other indications. Surgeries involving pedicled flap and revascularization are no longer used as contraindicati...

Authors: Jianhua Xu, Lu Yin, Shuming Cao, Haihua Zhan, Jianbing Zhang, Qiang Zhou and Ketong Gong

Etoricoxib is safe and effective in preventing heterotopic ossification after primary total hip arthroplasty

Heterotopic ossifications are a common complication after total hip arthroplasty. Low-dose radiation therapy and non-steroidal anti-inflammatory drugs have proven to effectively reduce the rate of heterotopic ...

Authors: Stella Oberberg, Jan Nottenkämper, Matthias Heukamp, Jan Krapp and Roland E. Willburger

The efficacy and safety of fast track surgery (FTS) in patients after hip fracture surgery: a meta-analysis

Fast track surgery (FTS) has been gradually applied in perioperative management of orthopedic surgery, but there still some research suspected that the prognosis of patients is not as expected and the cost is ...

Authors: Mingyang Jiang, Siyi Liu, Huachu Deng, Xuzhi Liang and Zhandong Bo

COVID-19 pandemic effects on orthopaedic surgeons in British Columbia

COVID-19 was declared a global emergency in the first quarter of 2020. It is has resulted in and continues in over a million deaths worldwide and halted medical systems and particularly elective surgeries worl...

Authors: Maciej J. K. Simon and William D. Regan

The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury

This study was designed to observe the expression of important hedgehog (Hh) signal factors in the bone tissue of rats with chronic fluorosis and cultured osteoblasts in order to investigate the role and signi...

Authors: Chaonan Deng, Lin Xu, Ying Zhang, Lina Zhao, Yan Linghu and Yanni Yu

Inter-rater variability of three-dimensional fracture reduction planning according to the educational background

Computer-assisted three-dimensional (3D) planning is increasingly delegated to biomedical engineers. So far, the described fracture reduction approaches rely strongly on the performance of the users. The goal ...

Authors: Christoph Zindel, Philipp Fürnstahl, Armando Hoch, Tobias Götschi, Andreas Schweizer, Ladislav Nagy and Simon Roner

The occurrence rate and clinical application of Osteo-line on the femur neck

This study was done to observe the incidence of Osteo-line on the femur neck and to explore the clinical application of Osteo-line in osteotomy.

Authors: Mingchen Zou, Haotian Wu, Shuangquan Yao, Dong Ren, Song Liu, Yueju Liu and Zhaohui Song