Articles

The efficacy of perioperative gabapentin for the treatment of postoperative pain following total knee and hip arthroplasty: a meta-analysis

Postoperative pain after total knee arthroplasty (TKA) and total hip arthroplasty (THA) influence patients’ rehabilitation and life quality. Although gabapentin has been widely used for analgesia, its efficacy...

Authors: Jiayu Kang, Zhihu Zhao, Jianwei Lv, Lei Sun, Bin Lu, Benchao Dong, Jianxiong Ma and Xinlong Ma

A multicenter mixed-effects model for inference and prediction of 72-h return visits to the emergency department for adult patients with trauma-related diagnoses

Emergency department (ED) return visits within 72 h may be a sign of poor quality of care and entail unnecessary use of healthcare resources. In this study, we compare the performance of two leading statistica...

Authors: Ehsan Yaghmaei, Louis Ehwerhemuepha, William Feaster, David Gibbs and Cyril Rakovski

Role of the SDF-1/CXCR4 signaling pathway in cartilage and subchondral bone in temporomandibular joint osteoarthritis induced by overloaded functional orthopedics in rats

To (i) use a mandibular advancement appliance in rats to investigate the role of the stromal cell-derived factor/CXC receptor 4 (SDF-1/CXCR4) signaling pathway in temporomandibular joint osteoarthritis (TMJ OA...

Authors: Jing Yang, Yazhen Li, Ying Liu, Qiang Zhang, Qi Zhang, Junbo Chen, Xiao Yan and Xiao Yuan

MRI evaluation of resorbable poly lactic-co-glycolic acid (PLGA) screws used in pelvic osteotomies in children—a retrospective case series

The orthopaedic use of resorbable poly lactic-co-glycolic acid (PLGA) implants carries multiple potential benefits. To our knowledge, only one publication exists regarding the use of PLGA implants in pelvic os...

Authors: Henrik Hedelin, Hanna Hebelka, Helena Brisby and Tero Laine

Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures

Complex regional pain syndrome type I (CRPS I) is a chronic devastating condition and a relatively common complication of distal radius fractures (DRF). The purpose of this study was to investigate the relatio...

Authors: Sang-Uk Lee, Ki-Tae Na, Yoon-Min Lee, Jong Hwa Park and Sun Young Joo

The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast

This study aimed to investigate the regulation of CpG oligodeoxynucleotides (ODNs) on proliferation and osteogenic differentiation of MC3T3 cells.

Authors: Wenwen Yu, Yi Zheng, Hongyan Li, Hongbing Lin, Zhen Chen, Yue Tian, Huishan Chen, Peipei Zhang, Xiaowei Xu and Yuqin Shen

Lumbar degenerative disease after oblique lateral interbody fusion: sagittal spinopelvic alignment and its impact on low back pain

We determined the incidence and risk factors of low back pain (LBP) in patients with lumbar degenerative disease after single-level oblique lateral interbody fusion (OLIF).

Authors: Jia Li, Di Zhang, Yong Shen and Xiangbei Qi

Cervical sagittal parameters were closely related to Neck Disability Index score after anterior cervical decompression and fusion

ACDF treatment of CSM is currently recognized as a surgical method with reliable efficacy. However, the cervical radiographic findings in a certain group of patients showed that the symptoms were not completel...

Authors: Yefu Xu, Sangni Liu, Feng Wang and Xiaotao Wu

In reply to the letter to the editor regarding “The Relationship Between Serum Vitamin D and Fracture Risk in the Elderly: A Meta-Analysis”

Authors: Ning Wang, Jindou Ji, Shengwen Yu, Jinlei Chang, Yungang Chen and Bo Yu

Italy and COVID-19: the changing patient flow in an orthopedic trauma center emergency department

Authors: Francesco Luceri, Ilaria Morelli, Riccardo Accetta, Laura Mangiavini, Nicola Maffulli and Giuseppe M. Peretti

The psychological impact on an orthopaedic outpatient setting in the early phase of the COVID-19 pandemic: a cross-sectional study

World Health Organization declared coronavirus disease-19 (COVID-19) a global pandemic on 11 March 2020, after the coronavirus claimed 4628 lives worldwide. Mental health challenges such as making impossible d...

Authors: Khai Cheong Wong, Xinyun Audrey Han, Kae Sian Tay, Suang Bee Koh and Tet Sen Howe

Relationship between potentially inappropriate medications and functional prognosis in elderly patients with distal radius fracture: a retrospective cohort study

Potentially inappropriate medications (PIMs) are a major concern in geriatric care. PIMs increase the risk of falls in elderly patients. However, the relationship between PIMs, subsequent falls, and functional...

Authors: Takako Nagai, Masahiro Nagaoka, Koji Tanimoto, Yoshiaki Tomizuka, Hiroshi Uei and Kazuyoshi Nakanishi

The biomechanical effect of different posterior tibial slopes on the tibiofemoral joint after posterior-stabilized total knee arthroplasty

Different posterior tibial slopes (PTS) after posterior-stabilized total knee arthroplasty (PS-TKA) may lead to different biomechanical characteristics of knee joint. This cadaveric study was designed to inves...

Authors: Yingpeng Wang, Songhua Yan, Jizhou Zeng and Kuan Zhang

The role of antibiotic-loaded bone cement in complicated knee arthroplasty: relevance of gentamicin allergy and benefit from revision surgery — a case control follow-up study and algorithmic approach

Antibiotic-loaded (particularly gentamicin) bone cement (BC) is widely used in total joint arthroplasty (TJA) to prevent periprosthetic infections (PPIs), but may itself cause implant failure. In light of a co...

Authors: Benjamin Thomas, Maria Benedikt, Ali Alamri, Florian Kapp, Rainer Bader, Burkhard Summer, Peter Thomas and Eva Oppel

Analysis of risk factors for revision in distal femoral fractures treated with lateral locking plate: a retrospective study in Chinese patients

To analyze the risk factors of revision operation after the treatment of distal femoral fracture with lateral locking plate (LLP).

Authors: Guojin Hou, Fang Zhou, Yun Tian, Hongquan Ji, Zhishan Zhang, Yan Guo, Yang Lv, Zhongwei Yang and Yawen Zhang

Efficacy and safety of a novel personalized navigation template in proximal femoral corrective osteotomy for the treatment of DDH

This present study is aimed to retrospectively evaluate the efficacy and safety of a novel personalized navigation template in proximal femoral corrective osteotomy for the treatment of DDH.

Authors: Qiang Shi and Deyi Sun

Metabolic factors and post-traumatic arthritis may influence the increased rate of surgical site infection in patients with human immunodeficiency virus following total hip arthroplasty

The impact of CD4+ T-cell count and highly active antiretroviral therapy (HAART) on the rate of surgical site infection (SSI) in patients with human immunodeficiency virus (HIV) undergoing total hip arthroplas...

Authors: Carol A. Lin, Phillip H. Behrens, Guy Paiement, W. David Hardy, James Mirocha, Robert L. Rettig, Heidi L. Kiziah, Andrew G. Rudikoff and Antonio Hernandez Conte

Adverse effects of total hip arthroplasty on the hip abductor and adductor muscle lengths and moment arms during gait

Precise evaluation of the hip abductor and adductor muscles function in total hip arthroplasty (THA) patients during gait could help prevent postoperative complications and optimize the rehabilitation training...

Authors: Xiangjun Hu, Nan Zheng, Wei-Chun Hsu, Jingwei Zhang, Huiwu Li, Yunsu Chen, Kerong Dai and Tsung-Yuan Tsai

A finite element analysis on comparing the stability of different posterior fixation methods for thoracic total en bloc spondylectomy

To compare the spinal stability with different fixation methods after thoracic TES using finite element analysis

Authors: Yun Liang, Yuanwu Cao, Zhiguo Gong, Chang Jiang, Lixia Jin, Zheng Li, Zixian Chen, Chun Jiang and Xiaoxing Jiang

Radiocarpal joint stiffness following surgical treatment for distal radius fractures: the incidence and associated factors

Postoperative radiocarpal joint stiffness (RJS) is common in patients with distal radius fractures (DRFs). The purpose of this study was to record the incidence of RJS and to determine potential risk factors t...

Authors: Lingde Kong, Yajie Zhai, Zuzhuo Zhang, Jian Lu, Bing Zhang and Dehu Tian

Preoperative anterior coverage of the medial acetabulum can predict postoperative anterior coverage and range of motion after periacetabular osteotomy: a cohort study

We hypothesized that preoperative pelvic morphology may affect postoperative anterior coverage and postoperative clinical range of motion (ROM) leading to postoperative pincer type femoroacetabular impingement...

Authors: Shinya Hayashi, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Tomoyuki Kamenaga, Takahiro Niikura and Ryosuke Kuroda

A possible injectable tissue engineered nucleus pulposus constructed with platelet-rich plasma and ADSCs in vitro

Injectable tissue engineered nucleus pulposus is a new idea for minimally invasive repair of degenerative intervertebral disc. The platelet-rich plasma (PRP) and adipose-derived stromal cells (ADSCs) could be ...

Authors: ZhiCheng Zhang, Jian Ma, DaJiang Ren and Fang Li

Bioinformatics analysis of differentially expressed genes in subchondral bone in early experimental osteoarthritis using microarray data

Osteoarthritis (OA) is the most common arthritic disease in humans, affecting the majority of individuals over 65 years of age. The aim of this study is to identify the gene expression profile specific to subc...

Authors: Zhao Wang, Yong Ji and Hong-wei Bao

Ultrasonic bone scalpel for thoracic spinal decompression: case series and technical note

Thoracic spinal stenosis (TSS) is a rare but intractable disease that fails to respond to conservative treatment. Thoracic spinal decompression, which is traditionally performed using high-speed drills and Ker...

Authors: Chuiguo Sun, Guanghui Chen, Tianqi Fan, Weishi Li, Zhaoqing Guo, Qiang Qi, Yan Zeng, Woquan Zhong and Zhongqiang Chen

Comparison between repeat anterior and posterior decompression and fusion in the treatment of two-level symptomatic adjacent segment disease after anterior cervical arthrodesis

Two-level symptomatic adjacent segment disease (ASD) is rarely reported, but remains a challenge after anterior cervical arthrodesis. The purpose of this study was to compare the clinical and radiological outc...

Authors: Junming Cao, Can Qi, Yipeng Yang, Tao Lei, Linfeng Wang and Yong Shen

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway

To clarify the role of apolipoprotein D (Apod) in alleviating glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells (MSCs) via the PI3K/Akt pathway, thus influencing the progres...

Authors: Rong-Hua Yu, Xiang-yang Zhang, Wei Xu, Zhi-kun Li and Xiao-dong Zhu

Letter to the Editor regarding “The relationship between serum vitamin D and fracture risk in the elderly: a meta-analysis”

Authors: Qiujiang Li, Xingxia Long and Lijun Cai

Knee OA cost comparison for hyaluronic acid and knee arthroplasty

Limiting treatment to those recommended by the American Academy of Orthopaedic Surgeon Clinical Practice Guidelines has been suggested to decrease costs by 45% in the year prior to total knee arthroplasty, but...

Authors: Kevin L. Ong, Faizan Niazi, Edmund Lau, Michael A. Mont, Andrew Concoff, Peter Shaw and Steven M. Kurtz

Functional deficits in chronic mechanical ankle instability

The interaction of functional and mechanical deficits in chronic ankle instability remains a major issue in current research. After an index sprain, some patients develop sufficient coping strategies, while ot...

Authors: Markus Wenning, Dominic Gehring, Marlene Mauch, Hagen Schmal, Ramona Ritzmann and Jochen Paul

Atorvastatin promotes bone formation in aged apoE^–/– mice through the Sirt1–Runx2 axis

Statins are the most widely used drugs in elderly patients; the most common clinical application of statins is in aged hyperlipemia patients. There are few studies on the effects and mechanisms of statins on b...

Authors: Wei Hong, Zhanying Wei, Zhaohui Qiu, Zheng Li, Chensheng Fu, Zhibin Ye and Xiaoya Xu

Percutaneous vertebroplasty with high- versus low-viscosity bone cement for osteoporotic vertebral compression fractures

There is no consensus on the best choice between high- and low-viscosity bone cement for percutaneous vertebroplasty (PVP). This study aimed to compare the clinical and radiological outcomes and leakage betwee...

Authors: Feng Miao, Xiaojun Zeng, Wei Wang and Zhou Zhao

Mid-term results of revision surgery using double-trabecular metal cups alone or combined with impaction bone grafting for complex acetabular defects

Revision surgery for complex acetabular defects is still technically challenging. In this study, we discussed and compared the clinical and radiological outcomes of revision surgery between two methods using d...

Authors: Xianghong Zhang, Zhihong Li, Wanchun Wang, Tang Liu and Weiqiu Peng

A succinct technique for the extraction of the proximal femoral nail anti-rotation (PFNA) after unlocking failure: a case report

Proximal femoral nail anti-rotation (PFNA) is a routine method to deal with intertrochanteric fractures in the elder population. It is challenging to remove PFNA in some cases as a result of stripping of blade...

Authors: Ming-de Cao, Zhong-Meng Yang and Hua-Ding Lu

Enhanced recovery after surgery (ERAS) program for elderly patients with short-level lumbar fusion

Degenerative disorders of the lumbar spine decrease the mobility and quality of life of elderly patients. Lumbar fusion surgery is the primary method of treating degenerative lumbar spine disorders; however, t...

Authors: Peng Wang, Qiang Wang, Chao Kong, Ze Teng, Zhongen Li, Sitao Zhang, Wenzhi Sun, Mingli Feng and Shibao Lu

Meta-analysis of serum and/or plasma D-dimer in the diagnosis of periprosthetic joint infection

The purpose of this meta-analysis was to evaluate the diagnostic value of D-dimer in detecting periprosthetic joint infection (PJI).

Authors: Cheng Li, Donara Margaryan, Cristina Ojeda-Thies, Carsten Perka and Andrej Trampuz

Infrapatellar fat pad resection or preservation during total knee arthroplasty: a meta-analysis of randomized controlled trials

The infrapatellar fat pad (IPFP) or Hoffa’s fat pad is often resected during total knee arthroplasty in order to improve visibility. However, the management of the IPFP during total knee arthroplasty (TKA) is ...

Authors: Changjiao Sun, Xiaofei Zhang, Woo Guan Lee, Yan Tu, Huimin Li, Xu Cai and Huadong Yang

Evaluation of the bone morphology around four types of porous metal implants placed in distal femur of ovariectomized rats

To compare structural features of the femoral bone of ovariectomized and non-ovariectomized rats after implantation of porous materials (TANTALUM, CONCELOC, TTM, ATLANT).

Authors: Stanislav Bondarenko, Nataliya Ashukina, Valentyna Maltseva, Gennadiy Ivanov, Ahmed Amine Badnaoui and Ran Schwarzkopf

A surgical reduction technique for posterior cruciate ligament avulsion fracture in total knee arthroplasty: a comparison study

Posterior cruciate ligament (PCL) avulsion fracture of the tibia is an uncommon but serious complication during primary cruciate-retaining total knee arthroplasty (TKA). The first objective of this report was ...

Authors: Wei Lin, Jinghui Niu, Yike Dai, Huaxing Zhang, Jing Zhu and Fei Wang

Incidence of deep venous thrombosis (DVT) of the lower extremity in patients undergoing surgeries for ankle fractures

To investigate the incidence of postoperative deep venous thrombosis (DVP) in patients undergoing surgeries for ankle fractures and identify the associated risk factors.

Authors: Luo Zixuan, Wei Chen, Yansen Li, Xiaomeng Wang, Weili Zhang, Yanbin Zhu and Fengqi Zhang

Comparisons of the surface micromotions of cementless femoral prosthesis in the horizontal and vertical levels: a network analysis of biomechanical studies

Numerous quantitatively biomechanical studies measuring the fixation stability of femoral stem using micromotions at the bone-implant interfaces in different directions and levels remain inconclusive. This net...

Authors: Bomin Wang, Qinghu Li, Jinlei Dong, Dongsheng Zhou and Fanxiao Liu

A propensity score-matched analysis comparing outpatient and short-stay hospitalization to standard inpatient hospitalization following total ankle arthroplasty

Given the trend toward value-based care, there has been increased interest in minimizing hospital length of stay (LOS) after orthopedic procedures. Outpatient total ankle arthroplasty (TAA) has become more pop...

Authors: Mark A. Plantz, Alain E. Sherman and Anish R. Kadakia

Interlaminar stabilization offers greater biomechanical advantage compared to interspinous stabilization after lumbar decompression: a finite element analysis

Interlaminar stabilization and interspinous stabilization are two newer minimally invasive methods for lumbar spine stabilization, used frequently in conjunction with lumbar decompression to treat lumbar steno...

Authors: Teng Lu and Yi Lu

Evaluation of risk factors of vertebral fracture in Japanese female patients with glucocorticoid-induced osteoporosis

Glucocorticoid-induced osteoporosis and vertebral fracture are common complications in patients on glucocorticoid treatment for rheumatological diseases. The present study aimed to identify the risk factors of...

Authors: Yu Mori, Takuya Izumiyama, Kazuyoshi Baba, Naoko Mori, Hiroshi Fujii, Tomonori Ishii and Eiji Itoi

Clinical features and treatment of “Non-dislocated hyperextension tibial plateau fracture”

To explore the epidemiological characteristics, clinical characteristics, treatment strategies, and clinical results of non-dislocated hyperextension tibial plateau fracture.

Authors: Jiang Liangjun, Zheng Qiang, Pan Zhijun, Zhu Hanxiao and Chen Erman

Comparison of bone morphogenetic protein and autologous grafting in the treatment of limb long bone nonunion: a systematic review and meta-analysis

Bone morphogenetic proteins (BMPs) have strong bone induction properties and can promote healing of fractures and other defects. However, BMP treatment efficacy for long bone nonunion remains controversial. Th...

Authors: Yong-Qiang Zhou, Hong-Liang Tu, Yan-Ji Duan and Xiao Chen

Bone defect reconstruction with a novel biomaterial containing calcium phosphate and aluminum oxide reinforcement

Reconstruction of metaphyseal fractures represents a clinical challenge for orthopedic surgeons. Especially in osteoporotic bone, these fractures are frequently accompanied by osseous substance defects. In ord...

Authors: Alexander M. Keppler, Maximilian M. Saller, Paolo Alberton, Ines Westphal, Frank Heidenau, Veronika Schönitzer, Wolfgang Böcker, Christian Kammerlander, Matthias Schieker, Attila Aszodi and Carl Neuerburg

Biomechanical investigation of external fixators for the treatment of supracondylar humerus fractures

Authors: Christoph Castellani, Holger Till and Annelie-Martina Weinberg

COVID-19: not a contraindication for surgery in patients with proximal femur fragility fractures

Authors: Ilaria Morelli, Francesco Luceri, Riccardo Giorgino, Riccardo Accetta, Paolo Perazzo, Laura Mangiavini, Nicola Maffulli and Giuseppe M. Peretti

BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B ...

Authors: Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang and Yuanshi Zhang

Surgical approach strategies for open reduction internal fixation of closed complex tibial Pilon fractures based on axial CT scans

To explore the application and clinical efficacy of surgical approach strategies in open reduction internal fixation of closed complex tibial Pilon fractures based on axial CT scans.

Authors: Yu Zhao, Jian Wu, Shijun Wei, Feng Xu, Changwang Kong, Xiaosong Zhi, Ming Huang and Xianhua Cai