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  1. Osteoporosis is a very common skeletal disorder that increases the risk of fractures. However, the treatment of osteoporosis is challenging. Hypoxia-inducible factor-1α (HIF-1α) plays an important role in bone...

    Authors: Luyao Li, Afang Li, Li Zhu, Liangying Gan and Li Zuo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:286
  2. The aim of this study is to compare the clinical and biomechanical outcome of INFIX plus single with two sacroiliac screw fixation for unstable pelvic fractures of Type C.

    Authors: Hongfen Chen, Chao Ding, Yongqiang Liu, Zhen Kong, Siling Chang, Feng Huang, Heng Li, Qingxiang Guo, Yuehua Yang, Hua Zhong and Shaozheng Yang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:285
  3. corticosteroid injection (CSI) has been used to treat greater trochanter pain syndrome (GTPS) for many years. However, so far, the efficacy of CSI in the treatment of GTPS is still controversial. Therefore, th...

    Authors: Yule Wang, Kaijin Wang, Yiling Qin, Sanrong Wang, Botao Tan, Lang Jia, Gongwei Jia and Lingchuan Niu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:283
  4. Quadratus lumborum block is a truncal block with several technique variations. It has been reported as providing effective analgesia for postoperative pain. The aim of this study is to determine the efficacy o...

    Authors: Haolan Xiong, Xiaohua Chen, Wenxiu Zhu, Wuke Yang and Fuming Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:282
  5. The present systematic review investigated possible factors which may influence the surgical outcome of minimally invasive surgery for total hip arthroplasty (MIS THA).

    Authors: Filippo Migliorini, Andrea Pintore, Joerg Eschweiler, Francesco Oliva, Frank Hildebrand and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:281
  6. To investigate the distribution and influence of comminution in femoral neck fracture (FNF) patients after cannulated screw fixation (CSF).

    Authors: Zhe Han, Wumti Taxi, Haobo Jia, NengNeng Ji, DongDong Cao, Xiang Sun, Chao Han, Mengqi Xie, Xinlong Ma and Qiang Dong
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:280
  7. The study carries the aim to compare the clinical efficacy and economic outcomes of using barbed suture closure versus conventional closure for wounds after posterior long-segment lumbar surgery.

    Authors: Kai Shi, Xuanwei Chen, Bin Shen, Yue Luo, Renqin Lin and Yu Huang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:279
  8. The study aim was to report the treatment outcomes of trochanteric flip osteotomy (TFO) with surgical hip dislocation (SHD) for femoral head fracture and dislocation (FHFD) and to investigate the risk factors ...

    Authors: Yong-Cheol Yoon, Chang-Wug Oh, Joon-Woo Kim, Jeong Heo and Hyung Keun Song
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:278
  9. Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the aging population. The correlation of radiographic OA severity, disability and pain is variable and inconsistent for the different ...

    Authors: Nicole Märtens, Vincent März, Jessica Bertrand, Christoph H. Lohmann and Alexander Berth
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:277
  10. To investigate the difference of trochlear width between normal and dysplastic trochlear and to analyze whether the medialization of trochlear groove was correlated with abnormal width of trochlear facets in t...

    Authors: Conglei Dong, Chao Zhao, Lingce Kong, Kang Piao, Kuo Hao and Fei Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:276
  11. The triple pelvic osteotomy is an established surgical method with multiple modifications regarding surgical technique and choice of implant. The stability of the osteotomy is affected by numerous factors, and...

    Authors: Henrik Hedelin, Erik Brynskog, Per Larnert, Johan Iraeus, Tero Laine and Kerstin Lagerstrand
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:275
  12. Patellar dislocation can cause a series of changes in the trochlear groove and patella. However, the influence of patellar dislocation on the medialis (VM) and vastus lateralis (VL) muscles and whether nerve g...

    Authors: Yu Wu, Weifeng Li, Shiyu Tang, Changli Liu, Gang Ji and Fei Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:274
  13. Tranexamic acid (TXA) has been shown to be effective at reducing peri-operative blood loss and haemarthrosis in arthroplasty and arthroscopic soft tissue reconstructions. Intra-articular application, as an inj...

    Authors: Scott M. Bolam, Arama O’Regan-Brown, Subhajit Konar, Karen E. Callon, Brendan Coleman, Nicola Dalbeth, A. Paul Monk, David S. Musson, Jillian Cornish and Jacob T. Munro
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:273
  14. We assessed the efficacy of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in patients with low-grade isthmic spondylolisthesis.

    Authors: Elsayed Mohamed Selim Ali, Tarek Abdelsamad El-Hewala, Amr Mohamed Eladawy and Reda Ali Sheta
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:272
  15. Proximal junctional failure (PJF) is a well-known complication after long-segment (at least 4 vertebral levels) instrumented fusion. The etiologies of PJF include degenerative processes or are fracture induced...

    Authors: Jen-Chung Liao, Wen-Jer Chen and Shiny Chih-Hsuan Wu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:271
  16. To construct a comprehensive simulation method of “gait-musculoskeletal system (MS)-finite element (FE)” for analysis of hip joint dynamics characteristics and the changes in the contact stress in the hip thro...

    Authors: Binglang Xiong, Peng Yang, Tianye Lin, Jingli Xu, Yong Xie, Yongliang Guo, Churong Liu, QIzhao Zhou, Qizhong Lai, Wei He, Qiushi Wei and Qingwen Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:267
  17. Anterior cruciate ligament (ACL) injury could lead to functional impairment along with disabilities. ACL reconstruction often fails owing to the regeneration failure of tendon–bone interface. Herein, we aimed ...

    Authors: Kai Kang, Qian Geng, Lukuan Cui, Lijie Wu, Lei Zhang, Tong Li, Qian Zhang and Shijun Gao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:266
  18. Non-specific low back pain (NLBP) is a major global socioeconomic burden, and the prevalence of NLBP is still on the rise. At present, there is no ideal drug to cure this disease. This may be the reason why pa...

    Authors: Yongfu Fan, Feilai Liu, Mengna Li, Xiaodi Ruan, Mingli Wu, Kaiqi Su, Jing Gao and Xiaodong Feng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:265
  19. To describe and analyze the morphological characteristics, location and frequency of pure transverse acetabular fracture lines through fracture mapping and quantitative measurements.

    Authors: Junran Li, Jingxiu Zhai, Yingchao Yin, Siyu Tian, Zhongzheng Wang, Ligeng Li, Zhiyong Hou and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:264
  20. The location of cephalic fixator tip with different eccentric distance (ED) should have different risks of cutout. This study aims to evaluate the cephalic fixator tip position by measuring ED of the cephalic ...

    Authors: Yun-fa Yang, Jian-wen Huang, Xiao-sheng Gao and Zhong-he Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:263
  21. Complex lower limb reconstruction due to severe trauma remains a challenge for reconstructive surgeons. Here, we introduce a modified donor blood flow-preserved cross-leg anterolateral thigh flap procedure and...

    Authors: Hong-Xiang Zhou, Liang He, Dong Yin, Yang Niu, Zhe Jin, Jun-Jie Li, Qian-Kun Wang and Tao Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:262
  22. Open reduction and internal fixation through the posterior approach are standard methods for treating middle-inferior humerus fractures. Given the limited operative field and difficulty in locating the radial ...

    Authors: Chaode Cen, Yongfei Cao, Yong Zhang, Chaoran Hu and Chunshan Luo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:260
  23. Periacetabular malignant tumor seriously endangers the life and health of patients. Hemipelvic replacement provides a good method for patients who want complete resection of the tumor while retaining or restor...

    Authors: Jun Li, Zicheng Liu, Dan Peng, Xia Chen, Chao Yu and Yi Shen
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:259
  24. Studies have given some pieces of evidence for the effect of total knee arthroplasty (TKA) on knee proprioception of patients with knee osteoarthritis (KOA), but their results were conflicting. This review was...

    Authors: Ya-Yue Xue, Jing-Nan Shi, Kuan Zhang, Hao-Hua Zhang and Song-Hua Yan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:258
  25. Intramedullary (IM) femoral alignment instrument is imprecise for the coronal alignment in total knee arthroplasty (TKA) in patients with severe lateral bowing of the femur, while the extramedullary (EM) align...

    Authors: Qianjin Wang, Xiaofeng Zhang, Tianshu Shi, Zhengyuan Bao, Bin Wang, Yao Yao, Dengxian Wu, Zheng Liu, Honggang Cai, Dongyang Chen, Jin Dai, Qing Jiang and Zhihong Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:257
  26. Few studies focus on the trauma-specific functional outcomes after surgical revascularization and risk factors contributing to poor outcomes in patients with acute blunt popliteal artery injury (PAI). The obje...

    Authors: Gang Liu, Jialei Chen and Zhou Xiang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:256
  27. Since Mohamed et al. analyzed 2326 orthopedic cases in 2002 and believed that the POSSUM formula can be directly used to predict postoperative morbidity and mortality in orthopedic patients, applications of PO...

    Authors: Feng Wanjiang, Zhang Xiaobo, Wu Xin, Meng Ye, Huang Lihua and Wang Jianlong
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:255
  28. Osteoarthritis is the most common type of degenerative joint disease and affects millions of people. In this paper, we propose a non-obtrusive and straightforward method to assess the progression of osteoarthr...

    Authors: Pavel Holeka, Filip Studnička, Damián Bušovský, Jan Štěpán, Jan Matyska and Jan Šlégr
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:254
  29. There is no consensus on anatomic landmarks or reference axes with which to accurately align rotational position of tibial component. Using the tibial tubercle, commonly referring to the Akagi line and the Ins...

    Authors: He Zhang, Chengming Cao, Han Zhang and Shoujiang Han
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:253
  30. Recent systematic reviews support that non-operative management should be the standard treatment for all stable isolated lateral malleolar fractures (ILMFs), regardless of fibular fracture displacement. Surgic...

    Authors: Jonas Ordell Frederiksen, Catarina Malmberg, Dennis Karimi, Peter Toft Tengberg, Anders Troelsen and Mads Terndrup
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:252
  31. We developed a mobile device application and dedicated pelvic positioner with the aim of improving the acetabular cup placement accuracy in patients undergoing total hip arthroplasty (THA). The function of the...

    Authors: Atsushi Kamimura, Makoto Enokida, Shinpei Enokida and Hideki Nagashima
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:251
  32. Anterior cruciate ligament plays a significant role in knee joint stability. It is claimed that the incidence of knee osteoarthritis increases in individuals with anterior cruciate ligament (ACL) rupture. The ...

    Authors: Hossein Akbari Aghdam, Farzaneh Haghighat, Mohammadreza Rezaie, Mahsa Kavyani and Mohammad Taghi Karimi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:250

    The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2022 17:294

  33. The obesity paradox, which suggests that high body weight is positively associated with survival in some diseases, has not been proven in patients with hip fracture. In this study, meta-analysis of previous st...

    Authors: Tzu-I Yang, Yu-Hang Chen, Ming-Hsiu Chiang, Yi-Jie Kuo and Yu-Pin Chen
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:249
  34. Because of the broad anatomic variation in the course of the axillary nerve, several cadaveric studies have investigated the acromion-axillary nerve distance and its association with the humeral length to pred...

    Authors: Cem Yildirim, Mehmet Demirel, Erhan Bayram, Mehmet Ekinci and Murat Yılmaz
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:248
  35. Patients who do not respond to conservative treatment of the isthmus are often treated with surgery. We used direct repair plus intersegment pedicle screw fixation for the treatment of lumbar spondylolysis. Th...

    Authors: Hao Meng, Yuan Gao, Peng Lu, Guang-Min Zhao, Zhi-Cheng Zhang, Tian-Sheng Sun and Fang Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:247
  36. miRNA-4701-5p has been reported to be a vital regulator in many diseases, including rheumatoid arthritis, and miRNA-4701-5p is evidenced to be participated in synovial invasion and joint destruction. In our re...

    Authors: Hui Zhang, Cheng Chen and Jie Song
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:246
  37. A discoid medial meniscus is rare in comparison with a discoid lateral meniscus. We encountered a new type of incomplete discoid with an oversized posterior segment. Therefore, this study aimed to report cases...

    Authors: Shotaro Araki, Masanori Tsubosaka, Hirotsugu Muratsu, Takao Inokuchi, Hiroaki Maruo, Hidetoshi Miya, Ryosuke Kuroda and Takehiko Matsushita
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:245
  38. Cortical suspensory fixation (CSF) devices gain more and more popularity as a reliable alternative to interference screws for graft fixation in anterior cruciate ligament (ACL) reconstruction. Adjustable-loop ...

    Authors: Sebastian Schützenberger, F. Keller, S. Grabner, D. Kontic, D. Schallmayer, M. Komjati and C. Fialka
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:244
  39. Despite Vast improvements in technology and surgical technique in total knee arthroplasty (TKA), approximately 15–25% TKAs, have suboptimal subjective clinical outcomes. Our study sought to evaluate if sensor-...

    Authors: Changjiao Sun, Zhe Zhao, Woo Guan Lee, Qi Ma, Xiaofei Zhang, Jianjin Zhu and Xu Cai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:243
  40. To compare one-stage freehand minimally invasive pedicle screw fixation (freehand MIPS) combined with mini-access surgery through OLIF approach with posterior approach for treatment of lumbar tuberculosis (TB)...

    Authors: Wenshuai Fan, Guangling Yang, Tianyao Zhou, Yanchao Chen, Zhenchao Gao, Weili Zhou and Yutong Gu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:242
  41. The purpose of this study was to evaluate the efficacy of intrathecal morphine (ITM) in combination with bupivacaine as pre-emptive analgesia in patients undergoing posterior lumbar fusion surgery. This is in ...

    Authors: R. Trivedi, J. John, A. Ghodke, J. Trivedi, S. Munigangaiah, S. Dheerendra, B. Balain, M. Ockendon and J. Kuiper
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:241
  42. To explore the effects and deficiencies of the enhanced recovery after surgery (ERAS) care protocol on patients undergoing lumbar fusion and internal fixation in perioperative care.

    Authors: Zengmei Sun and Yanqiu Qi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:240
  43. Though alignment of the spine and lower extremities in the standing neutral position has been evaluated, a few studies evaluating the alignment of the upper extremities have also been made. This study assessed...

    Authors: Yuki Yoshida, Noboru Matsumura, Yoshitake Yamada, Satoshi Hiraga, Kazunori Ishii, Satoshi Oki, Yoichi Yokoyama, Minoru Yamada, Masaya Nakamura, Takeo Nagura and Masahiro Jinzaki
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:239
  44. LncRNA PRNCR1 has been reported to be involved in LPS-induced inflammation, which contributes to osteoarthritis (OA). We predicted that miR-377-3p could bind to PRNCR1.MiR-377-3p can suppress OA development. W...

    Authors: Guan Wang, Chunhong Li, Xihai Zhang, Lian Tang and Yao Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:238
  45. To systematically review the literature and provide a comprehensive understanding of the preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery.

    Authors: Zhao Chen, Jialei Chen, Rong Luo, Jiabao Jiang and Zhou Xiang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:237

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