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  1. Adolescent idiopathic scoliosis (AIS) is the most prevalent type of scoliosis affecting children between the ages of 10–16 years. However, risk factors for AIS, particularly the modifiable ones, are still larg...

    Authors: Jingfan Yang, Sizhe Huang, Mengyuan Cheng, Weiqing Tan and Junlin Yang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:472
  2. Knee osteoarthritis (KOA) with varus alignment and medial space stenosis is a common degenerative disorder in the elderly. To reallocate the force bearing from the medial to the lateral compartment, the anti-v...

    Authors: Zhan-Xiong Wu, Wen-Xia Ren and Zhi-Qiang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:470
  3. To investigate the change of the cross-sectional area (CSA) of vastus medialis oblique (VMO) in patients with recurrent patellar dislocation (RPD) treated by tibial tubercle transfer combined with medial patel...

    Authors: Chao Zhao, Conglei Dong, Xiaomeng Wang, Lingce Kong, Bo Chang and Fei Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:469
  4. Deer antler is a traditional Chinese medicine with the function of tonifying kidney and strengthening bone, which is often used to treat orthopedic diseases.

    Authors: Jianyu Wang, Yuchi Wei, Zhenwei Zhou, Jie Yang, Yuyan Jia, Hailong Wu, Haisi Dong and Xiangyang Leng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:468
  5. Studies have reported mixed results on the importance of medial calcar support for the treatment of proximal humeral fractures. The purpose of this study was to compare radiographic and functional outcomes of ...

    Authors: Chun-Yu Hung, Chia-Yi Yeh, Po-Chong Wen, Wen-Ling Yeh and Shih-Jie Lin
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:467
  6. Different surgical techniques have been proposed to reconstruct combined anterior cruciate (ACL) and lateral collateral ligaments (LCL). Although these surgical techniques are reliable and reproducible, the nu...

    Authors: Sérgio Rocha Piedade, Carlos Górios, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:466
  7. Regenerative therapy using platelet-rich plasma (PRP), a rich source of growth factors, has become popular in orthopedic sports medicine. Elite athletes prefer PRP therapy for their injured muscles and tendons...

    Authors: Tomoharu Mochizuki, Takashi Ushiki, Satoshi Watanabe, Go Omori and Tomoyuki Kawase
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:465
  8. Remnant-preserving anterior cruciate ligament reconstruction (ACLR) should have advantages for postoperative remodeling and proprioception. However, it has been suggested that the larger diameter of the graft ...

    Authors: Sebastian Bierke, Martin Häner, Katrin Karpinski, Tilman Hees and Wolf Petersen
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:463
  9. It is unclear what role COL1A1 polymorphisms play in anterior cruciate ligament (ACL) injury pathophysiology. The present study investigated the relationship between COL1A1-1997 guanine (G)/thymine (T) (rs1107946...

    Authors: Seyed Peyman Mirghaderi, Maryam Salimi, Majid Kheirollahi, Seyed Mohammad Javad Mortazavi and Hossein Akbari-Aghdam
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:462
  10. The purpose of this study is to describe the midterm clinical and radiologic outcomes of concurrent femoral head reduction osteotomy (FHRO) and periacetabular osteotomy (PAO) in Legg–Calvé–Perthes disease (LCP...

    Authors: Kaveh Gharanizadeh, Hadi Ravanbod, Amir Aminian and Seyed Peyman Mirghaderi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:461
  11. The arthroscopic Broström–Gould procedure (ABG) gained particular attention among clinicians and researchers due to its high rate of satisfactory results. There is a lack of evidence regarding the differences ...

    Authors: Jinlang Liu, Mingliang Chen, Tao Xu, Zhipeng Tian, Liuhai Xu and You Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:459
  12. Resection of tarsal coalitions provides good patient satisfaction scores, reduced pain, and improved long-term function in both athletic and non-athletic populations. This study aimed to determine when athleti...

    Authors: Amol Saxena, Ryan Allen, Anthony Wright, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:458
  13. Total hip arthroplasties (THA) are cost-effective interventions for patients with osteoarthritis refractory to physical therapy or medical management. Most individuals report positive surgical outcomes with re...

    Authors: John P. O’Connor, Paige Holden and Joel J. Gagnier
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:457
  14. This study examined the impact of Mobidisc implant on spinopelvic parameters, with particular focus on the preservation of the lumbar lordosis (LL) and on the segmental lordosis (SL) of the treated and adjacen...

    Authors: Samir Smajic, Aleksandar Vujadinovic, Adnan Kasapovic, Dakheel A. Aldakheel, Yann Philippe Charles, Axel Walter, Jean-Paul Steib, Nicola Maffulli, Filippo Migliorini and Alice Baroncini
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:456
  15. Apart from the current understanding of enzyme function, the mechanism of ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) deficiency-associated osteoporosis is unknown. We aimed to explore the changes ...

    Authors: Qiang Wang, Zhiqiang Gao, Kai Guo, Jiawei Lu, Feng Wang, Yufeng Huang and Desheng Wu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:455
  16. We aimed to investigate the utility of Hounsfield units (HU) obtained from different regions of interest in opportunistic lumbar computed tomography (CT) to predict osteoporosis coupling with data of dual-ener...

    Authors: Guangyue Yang, Hansong Wang, Zhufeng Wu, Yinyu Shi and Yongfang Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:454
  17. Osteoarthritis (OA) is a chronic disease that involves chondrocyte injury and dysfunction. CircRNAs participate in OA progression, but the roles of circRNAs in the occurrence of OA are unclear. In this study, ...

    Authors: Shengbin Shuai, Qianqian Cai and Yunxia Ou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:452
  18. We aimed to construct a nonlinear regression model through Extreme Gradient Boost (XGBoost) to predict functional outcome 1 year after surgical decompression for patients with acute spinal cord injury (SCI) an...

    Authors: Zhan Sizheng, Huang Boxuan, Xue Feng and Zhang Dianying
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:451
  19. Total knee arthroplasty (TKA) is an established surgical treatment for advanced knee osteoarthritis by which patients can expect improvement of knee pain and function. Although many surgeons have investigated ...

    Authors: Arata Nakajima, Masato Sonobe, Yorikazu Akatsu, Manabu Yamada, Keiichiro Yamamoto, Junya Saito, Masaki Norimoto, Keita Koyama, Shinji Taniguchi, Hiroshi Takahashi, Yasuchika Aoki, Toru Suguro and Koichi Nakagawa
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:450
  20. Osteochondral lesions of the talus (OLTs) are a common orthopedic condition. The image presentation is very similar to that of ischemic necrosis of the talus complicated by a talar neck fracture, but the two a...

    Authors: Qitao Song, Xiantie Zeng, Haijing Huang, Lei Long, Jin Xu, Shuangshuang Cui, Zhonghai Li and Xinlong Ma
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:449
  21. Distal clavicular fracture is a shoulder joint injury that is common in clinical settings and is generally surgically treated using the clavicular hook plate technique with a confirmed curative effect. However...

    Authors: Dashuang Li, Rui Qiao, Na Yang, Kun Zhang, Yangjun Zhu and Zhe Song
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:448
  22. Previous studies have demonstrated that by injecting uPA into the lumbar facet joints (LFJ) of normal rats, a rat LFJOA animal model can be successfully established. However, there is no evidence that intraart...

    Authors: Di Yang, Wei Hu, Hao Li, Yin-chu Shao, Ji-chun Shan, Xu Xiong and Feng Shuang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:447
  23. There is conflicting clinical evidence whether platelet-rich plasma (PRP) therapies could translate to an increased meniscus healing rate and improved functional outcomes. The objective of this systematic revi...

    Authors: Ziquan Li and Xisheng Weng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:446
  24. Ultraviolet (UV) light-mediated photofunctionalization improves the osseointegration of pure titanium and titanium alloy (Ti6Al4V). However, little is known about the effect of UV irradiation on Ti6Al4V, used ...

    Authors: Shengdao Jin, Yuji Yamamoto, Yoshifumi Harada, Sho Kaneko, Kazuki Oishi and Yasuyuki Ishibashi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:445
  25. Fractures of the posterior process of the talus are rarely seen and frequently overlooked. In our study, anatomical observation and classification of the posterior process of the talus were carried out, and re...

    Authors: Han Yang, Liqing Liao, Fan Xue, Yikai Li and Guanyu Hu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:444
  26. Medical devices are used in almost all orthopedic surgical subspecialties, and the frequency of adverse events is increasing, which should not be ignored. To provide suggestions on how to avoid implant recalls...

    Authors: Yang Wang, Kai Xu, Yuchen Wang, Weijie Ye, Xinyi Hao, Shouli Wang, Kun Li and Jun Du
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:443
  27. Recent studies have found that C2-FH is close to 0 cm in both standing and sitting position for asymptomatic adults. We hypothesize that the thoracic spine may compensate with PJK when the immediate post-opera...

    Authors: Xin Zhang, Shibin Shu, Zezhang Zhu, Qi Gu, Zhen Liu, Yong Qiu and Hongda Bao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:442
  28. Hip preservation therapy of early ONFH (Osteonecrosis of the femoral head) has emerged as one of the hot areas of research. We have optimized the procedure of traditional MFCVBG (medial femoral circumflex vasc...

    Authors: Yingkai Zhang, Xinyuan Wang, Chang Jiang, Bingxuan Hua and Zuoqin Yan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:441
  29. Conditions affecting skeletal muscle, such as chronic rotator cuff tears, low back pain, dystrophies, and many others, often share changes in muscle phenotype: intramuscular adipose and fibrotic tissue increas...

    Authors: Severin Ruoss, Mary C. Esparza, Laura S. Vasquez-Bolanos, Chanond A. Nasamran, Kathleen M. Fisch, Adam J. Engler and Samuel R. Ward
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:440
  30. Posterior wall acetabular fractures remain one of the most difficult fracture injuries to treat. Accurate assessment of fracture characteristics and appropriate preoperative surgical strategies are essential f...

    Authors: Jianan Chen, Yifan Zheng, Zhixun Fang, Wei Zhou, Dan Xu, Guodong Wang, Xianhua Cai and Ximing Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:439
  31. Although the relatively high incidence of coronal fractures in the supracondylar–intercondylar fractures is well established, little is currently known about the morphology of those fractures. Herein, we chara...

    Authors: Yin Ding, Dong Wang, Muhammad Zeeshan Waheed and Jun-Lin Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:438
  32. Evaluation of micromotion in various activities in daily life is essential to the assessment of the initial fixation of cementless short stems in total hip arthroplasty. This study sought to evaluate three-dim...

    Authors: Arata Kanaizumi, Daisuke Suzuki, Satoshi Nagoya, Atsushi Teramoto and Toshihiko Yamashita
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:437
  33. Developmental dysplasia of the hip (DDH) is a musculoskeletal disorder. Genetic and epigenetic changes in C-X3-C motif chemokine receptor 1 (CX3CR1) may lead to disturbance in chondrocyte development and change t...

    Authors: Mohammad Nejadhosseinian, Hoda Haerian, Reza Shirkoohi, Jafar Karami and Seyed Mohammad Javad Mortazavi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:436
  34. Gastrocnemius tendon lengthening is performed to treat numerous conditions of the foot and ankle. Gastrocnemius shortening has been associated with more than 30 lower limb disorders, including plantar heel pai...

    Authors: Álvaro Iborra Marcos, Manuel Villanueva Martínez and Homid Fahandezh-Saddi Díaz
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:435
  35. Shoulder stiffness resulting in motion loss can be caused by numerous conditions, the most common of which is adhesive capsulitis. Surgical intervention is often necessary when conservative methods fail. High-...

    Authors: Shaun Stinton, Samantha Beckley, Alicia Salamani, Devinne Dietz and Thomas Branch
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:434
  36. Tennis elbow has long been one of the most controversial subjects in orthopaedics. Many scholars thought the use of open or arthroscopic surgery was reserved for patients with refractory symptoms. Therapy with...

    Authors: Lin-Pu Ge, Xiao-Qian Liu, Rui-Kun Zhang, Zhi-Neng Chen and Feng Cheng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:433
  37. Intervertebral disc degeneration (IDD) has become a serious public health problem, the mechanism of which is complex and still unclear. We aimed to construct a ceRNA network related to IDD to explore its patho...

    Authors: Xiaoyang Fang, Tian Tang, Daoxi Sun, Shuang Chen, Nan Wang and Lin Xie
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:432
  38. To observe the effect of enoxaparin sodium-polymethyl methacrylate (ES-PMMA) bone cement supplemented with alendronate (AN) on bone repair of bone defects in New Zealand rabbits.

    Authors: Zhihang Xiao, Dehao Fu, Li Zhang, Weiye Fan, Xiaoyu Shen and Xiangbei Qi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:431
  39. To investigate the association between the level of glycosylated hemoglobin (HbA1c) and preoperative deep vein thrombosis (DVT) and that between diabetes mellitus (DM) and preoperative DVT in patient undergoin...

    Authors: Xiaojuan Xiong, Ting Li and Bo Cheng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:430
  40. Total knee arthroplasty (TKA) is a standard treatment for end-stage degenerative knee disease. Most patients will experience moderate-to-severe postoperative knee pain, significantly affecting rehabilitation. ...

    Authors: Xiumei Tang, Yahao Lai, Siwei Du and Ning Ning
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:429
  41. Circular RNAs are involved in various cellular processes of bone diseases by acting as miRNA sponges to regulate gene expression levels, including osteosarcoma (OS). This research concentrated on the molecular...

    Authors: Zhong Huang, Pengcheng Chen, Ruipeng Jia and Yiheng Liu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:428
  42. Advancements in medicine and the popularity of lumbar fusion surgery have made lumbar adjacent segment disease (ASDz) increasingly common, but there is no mature plan for guiding its surgical treatment. Theref...

    Authors: Jincheng Wu, Dongmei Yang, Ye Han, Hanpeng Xu, Wangqiang Wen, Haoxiang Xu, Kepeng Li, Yong Liu and Jun Miao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:427
  43. Oblique lateral lumbar interbody fusion (OLIF) is one of the most widely used lumbar interbody fusion procedures in clinical practice. The aim of this study was to minimize the incidence rate of surgical compl...

    Authors: Meng-long Han, Wei-hong He, Zhong-yun He, Xue-liang Yan and Xiang-jun Fang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:426
  44. The purpose of this study was to overview the findings of reported meta-analyses on unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO).

    Authors: Hangyu Ping, Jiaxin Wen, Yubo Liu, Haifeng Li, Xin Wang, Xiangpeng Kong and Wei Chai
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:425
  45. Shilajit has been widely used remedy for treating a numerous of illness such as bone defects in Iran traditional folk medicine since hundreds of years ago. The aim of the present study was to explore the effec...

    Authors: Parisa Kangari, Leila Roshangar, Aida Iraji, Tahereh Talaei-Khozani and Mahboobeh Razmkhah
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:424
  46. Osteoporosis (OP) is a common metabolic bone disease mainly involving bone remodeling and blood vessels. The current study aimed to explore the role of zinc finger E-box binding homeobox 1 (ZEB1) in OP.

    Authors: Xianwei Zhu, Fei Yan, Lipeng Liu and Qun Huang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:423
  47. Traumatic heterotopic ossification (tHO) is characterized by ectopic bone formation in extra-skeletal sites leading to impaired wound healing, entrapment of neurovascular structures, pain, and reduced range of...

    Authors: Philip J. Spreadborough, Amy L. Strong, John Mares, Benjamin Levi and Thomas A. Davis
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:422

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