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Table 2 Univariate meta-regression analysis for the effects of n-3 PUFA on joint pain in patients with OA

From: Effect of omega-3 polyunsaturated fatty acids supplementation for patients with osteoarthritis: a meta-analysis

Covariate

Pain

Coefficient

95% CI

p

Patient number

0.0003

− 0.0001 to 0.0007

0.16

Mean age (years)

0.031

− 0.012 to 0.073

0.13

Men (%)

0.0092

− 0.0117 to 0.0301

0.33

n-3 PUFA dose (mg/d)

− 0.0002

− 0.0006 to 0.0002

0.21

EPA dose (mg/d)

0.0001

− 0.0012 to 0.0014

0.82

DHA dose (mg/d)

− 0.0003

− 0.0007 to 0.0001

0.18

Follow-up duration (months)

0.005

− 0.003 to 0.013

0.18

  1. CI confidence interval; n-3 PUFA omega-3 polyunsaturated fatty acids; OA osteoarthritis; EPA eicosapentaenoic acid; DHA docosahexanoic acid