Combination of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio with plasma D-dimer level to improve the diagnosis of deep venous thrombosis (DVT) following ankle fracture

Table 3 Relationship between PLR and preoperative DVT investigated by total adjusted multivariate logistic regression model

Variables	OR and 95% CI	P
PLR	2.84 (1.80–4.47)	< 0.001
Age	1.04 (1.02–1.05)	< 0.001
Gender (male vs female)	2.12 (1.21–3.76)	0.027
Obesity (BMI ≥ 28.0 kg/m²)	1.23 (0.62–2.45)	0.558
Smoking	0.76 (0.42–1.41)	0.387
Alcohol drinking	1.30 (0.73–2.32)	0.380
Time from fracture to DUS examination	1.15 (1.08–1.22)	< 0.001
Fracture type
Unimalleolar	Reference
Bimalleolar	0.83 (0.45–1.53)	0.551
Trimalleolar	0.83 (0.47–1.49)	0.538
Dislocation/subluxation	1.33 (0.76–2.33)	0.316
Mechanism (high- versus low-energy)	1.38 (0.84–2.26)	0.202
Hypertension	1.37 (0.72–2.60)	0.342
Diabetes mellitus	1.43 (0.78–2.63)	0.247
Cerebrovascular disease	0.87 (0.16–4.84)	0.872
Heart disease	1.29 (0.41–8.84)	0.088
Liver disease	2.01 (0.61–6.59)	0.251
D-dimer (> 0.80 mg/L)	2.91 (1.79–4.76)	< 0.001

PLR—platelet to lymphocyte rate, BMI—body mass index, OR—odd ratio, CI—confidence interval

ISSN: 1749-799X