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Table 2 Revised association of MC1 with pain on provocative discography

From: Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability

Study

MC1 association with pain on provocation discography OR (95% CI)

Herlin et al.

This review

Braithwaite [58]

9.58 (0.52, 176.75)

9.58 (0.52, 176.75)

Thompson [53]

9.32 (6.17, 14.09)

10.19 (6.74, 15.42)

O’Neill [52]

7.90 (1.79, 34.97)

7.90 (1.78, 34.97)

Weishaupt [51]

13.59 (2.92, 63.28)

18.20 (3.86, 85.90)

Kokkonen [59]

1.34 (0.48, 4.00)

1.11 (0.37, 3.36)

Aggregated MC1 OR

6.14 (2.47, 15.27)

8.34 (5.86, 11.87)