Fig. 5
From: CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma
Effects of CPEB2 and ARPC5 on MM cell growth and angiogenesis. OPM2 cells were co-transfected with sh-CPEB2 and pc-ARPC5, and U266 cells were co-transfected with pc-CPEB2 and sh-ARPC5. A, B ARPC5 mRNA and protein expression levels were detected by qRT-PCR and western blot analysis. C CCK8 assay was used to detect cell viability. D Soft-agar colony formation assay was employed to examine colony number. E Cell apoptosis ratio was tested using flow cytometry. F Tube formation assay was performed to measure angiogenesis ability. Cell experiment was repeated three times. Data were expressed as mean ± SD, and one-way ANOVA followed by Tukey post hoc test was used to compare data between multiple groups. **P < 0.01, ***P < 0.001