Fig. 3

Circ_0005615 sponged miR-331-3p. A The binding sites between circ_0005615 and miR-331-3p were exerted. B QRT-PCR was conducted to test the transfection efficiency of miR-331-3p mimic. C, D The interaction between miR-331-3p and circ_0005615 was demonstrated via Dual-luciferase reporter assay. E The level of miR-331-3p in MM patients and healthy volunteers was investigated by qRT-PCR. F Pearson correlation analysis was exploited to illustrate the correlation between circ_0005615 and miR-331-3p. G QRT-PCR was performed to calculate the level of miR-331-3p in MM cells and nPCs cells. ***P < 0.001, ****P < 0.0001