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Table 8 MDR analysis of the interaction of LRP5 gene rs41494349, rs2306862 and LRP6 gene rs10743980, rs2302685 alleles with the menopausal years

From: LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women

Gene-age interaction

 

Training balancing accuracy

Testing accuracy

OR (95% CI)

P-value

Cross-validation consistency

1

rs2306862&Age

0.514

0.492

1.030 (0.984, 1.078)

0.208

10/10

 

rs2302685& Age

0.532

0.517

1.024 (0.994, 1.056)

0.122

9/10

2

rs2306862&rs10743980& Menopausal years

0.578

0.552

1.011 (0.987, 1.035)

0.378

10/10

3

rs41494349&rs2302685&rs10743980& Menopausal years

0.548

0.532

1.013 (0.987, 1.040)

0.324

10/10

  1. SNP single-nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. Adjusted for age, *P<0.05, **P<0.01
  3. Italicized value is statistically significant, *P < 0.05, *P<0.01 indicates statistical significance
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X