Fig. 2From: LncRNA ZFAS1 protects chondrocytes from IL-1β-induced apoptosis and extracellular matrix degradation via regulating miR-7-5p/FLRT2 axisOverexpression of ZFAS1 ameliorated the apoptosis and ECM degradation in IL-1β-treated chondrocytes. A The expression of ZFAS1 was detected in chondrocytes treated with empty vector or ZFAS1 overexpression vector or without any treatment. **P < 0.01 compared with the vector group. B The effects of ZFAS1 overexpression on the cell viability of IL-1β-treated chondrocytes. *P < 0.05, **P < 0.01. C The effects of ZFAS1 overexpression on the apoptosis rate of IL-1β-treated chondrocytes. **P < 0.01, compared with control group; ##P < 0.01, compared with IL-1β group. D Relative expression levels of MMP13, ADAMTS5, Collagen II, and Aggrecan measured by western blot analysis. **P < 0.01, compared with control group; #P < 0.05, ##P < 0.01, compared with IL-1β groupBack to article page