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Table 2 Multivariate Cox analysis of prognostic factors in patients with osteosarcoma based on the overall survival

From: EPB41L4A-AS1 and UNC5B-AS1 have diagnostic and prognostic significance in osteosarcoma

Parameter

Cumulative overall survival

HR

95%CI

P

EPB41L4A-AS1 (High vs. Low)

5.997

1.845–19.486

0.003**

UNC5B-AS1 (High vs. Low)

5.911

1.828–19.18

0.003**

Age (≥ 18 years vs. < 18 years)

1.144

0.437–2.996

0.784

Gender (Male vs. Female)

2.085

0.761–5.713

0.153

Tumor site

   

Femur

Reference

  

Tibia

0.509

0.134–1.927

0.320

Humeral bone

1.078

0.265–4.381

0.917

Other

1.134

0.226–5.684

0.878

SSS stage (III vs. I–II)

4.676

1.430–15.291

0.011*

LDH (≥ 850 IU/L vs. < 850 IU/L)

1.842

0.667–5.086

0.238

ALP (≥ 280 IU/L vs. < 280 IU/L)

1.452

0.566–3.724

0.437

  1. LDH, lactate dehydrogenase; ALP, alkaline phosphatase
  2. *P < 0.05, **P < 0.01. SSS: surgical staging system