Table 2 Intraoperative data (ITT analysis)

Anesthesia time (min)

188 (145–250)

197 (170–254)

185 (160–230)

0.168^a

Surgery time (min)

119 (84–162)

135 (107–171)

125 (99–159)

0.063^a

Cumulative amount of infused volume (ml)

2575

(2000–4210)

2435

(1760–3480)

2210

(1658–3000)

0.063^a

Crystalloids (ml)

2250

(1750–3000)

725

(500–1000)

1500

(1000–2000)

 < 0.001^a

Colloids (ml)

0

(0–0)

1250

(1000–1750)

500

(500–1000)

 < 0.001^a

Median SV (ml)

65 (54–74)

67.5 (60–75.25)

-

0.96^c

Inotropes (%)

19 (28.8%)

28 (21.5%)

18 (13.8%)

 < 0.001^b

Blood transfusion (%)

18 (27.3%)

57 (43.8%)

47 (36.2%)

0.071^b

Intraoperative blood loss (ml)

800

(475–1200)

1000

(500–1500)

800

(485–1500)

0.562^a

Necessity NE

25 (37.9%)

20 (25.4%)

31 (40.3%)

0.002

Average max. NE-dose (µg/kg Bodyweight/min)

0.027

0.0133

0.0191

0.004^a

NE at end of surgery

10 (15.2%)

10 (7.7%)

18 (13.8%)

0.185^b

Postoperative admission to

0.223^b

 Recovery room

45 (68.2%)

71 (54.6%)

75 (57.7%)

 PACU

18 (27.3%)

53 (40.8%)

44 (33.8%)

 ICU

3 (4.5%)

6 (4.6%)

11 (8.5%)

LOS

 Recovery room (min)

150 (115.5–190)

160 (110–205)

170 (120–240)

0.177^a

 PACU/ICU (min)

750 (427.5–1235)

400 (207–825)

960 (360–1210)

 < 0.001^a