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Table 3 Comparing the performance of the classification in identifying soft tissue tumor differentiation in previous and current studies

From: Tumor-to-bone distance and radiomic features on MRI distinguish intramuscular lipomas from well-differentiated liposarcomas

Study

Number of patients with lipomas in benign group

Number of patients with ALTs/WDLSs in malignant group

Classify

Machine learning algorithm

AUC

Sensitivity (%)

Specificity (%)

Accuracy (%)

Cay, 2022 [15]

45

20/20 (100%)

Lipomas vs. ALTs/WDLSs

SVM

0.98

96.8

93.7

–

Fradet, 2022 [16]

40

45/45 (100%)

Lipomas vs. ALTs

Logistic regression

0.50

100

0.0

–

    

SVM

0.47

70.0

32.0

–

    

Random forest

0.71

64.0

68.0

–

    

Gradient boosting

0.70

67.0

64.0

–

Tang, 2022 [20]

90

32/32 (100%)

Lipomas vs. ALTs

Random forest

0.94

85.7

100

96.0

Yang, 2022 [23]

69

58/58 (100%)

Lipomas vs. WDLSs

SVM

0.95

95.0

88.9

92.1

Malinauskaite, 2020 [18]

24

5/14 (35.7%)

Lipomas vs. Liposarcomas

SVM

0.93

88.8

100

94.7

    

LDA

0.93

–

–

89.5

    

Naïve Bayes

0.81

–

–

79.0

    

Logistic regression

0.812

–

–

73.7

Leporq, 2020 [17]

40

?/41

Lipomas vs. Liposarcomas

SVM

0.96

100

90

95.0

Vos, 2019 [22]

58

58/80 (71.6%)

Lipomas vs. WDLSs

Various*

0.83

68

84

67.0

Thornhill, 2014 [21]

24

?/20

Lipomas vs. Liposarcomas

LDA

N/A

85

96

91.0

Current study

 Machine learning model

38

30/30 (100%)

IM lipomas vs. ALTs/WDLSs

LASSO LR

0.88

91.6

85.7

89.0

 MSK radiologist 1

38

30/30 (100%)

IM lipomas vs. ALTs/WDLSs

-

0.94

97.4

90.9

95.0

 MSK radiologist 2

38

30/30 (100%)

IM lipomas vs. ALTs/WDLSs

-

0.91

100

81.8

93.3

  1. IM lipomas intramuscular lipomas, ALTs/WDLSs atypical lipomatous tumors/well-differentiated liposarcomas, MSK radiologist musculoskeletal radiologist, LASSO LR Least Absolute Shrinkage and Selection Operator (LASSO) logistic regression, AUC area under the curve, N/A not available
  2. *The model was constructed using various methods including logistic regression, support vector machine (SVM), random forests, naïve Bayes, linear discriminant analysis (LDA), and quadratic discriminant analysis (QDA)