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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Aspirin prevents estrogen deficiency-induced bone loss by inhibiting osteoclastogenesis and promoting osteogenesis

Fig. 5

Aspirin prevented OVX-induced bone loss in vivo. A Representative images of Micro-CT in sham, OVX and aspirin treatment (low and high doses) groups. B–E Quantitative analyses of bone microstructure parameters, including BV/TV, Tb.N, Tb.Th and Tb.Sp. F Representative images of TRAP and OCN immunohistochemical staining in sham, OVX and different doses of aspirin treatment groups. Scale bar = 50 μm. G–I Quantitative analyses of osteoclast number/bone surface (N.Oc/BS), osteoclast surface/bone surface (Oc.S/BS) and OCN positive cells ratios. *P < 0.05, **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X