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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Circ_0000479 promotes proliferation, invasion, migration and inflammation and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes via miR-766/FKBP5 axis

Fig. 6

Circ_0000479 affected MH7A cell progression through FKBP5. A B The relative mRNA and protein levels of FKBP5 in MH7A cells were measured by qRT-PCR and western blot analysis. C, D The proliferation and apoptosis of MH7A cells were estimated by CCK-8 and flow cytometry analysis. E, F The invasion and migration of MH7A cells were assessed by transwell and wound-healing assays. G The positive expression of TNF-α, IL-6 and IL-1β in MH7A cells were examined by ELISA kits. Magnification 40 × for wound healing assays and 100 × for transwell assays. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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