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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

Fig. 7

Down-regulation of VEGF signaling was restored by BSHX formula. Representative IHC images and qualification of VEGF (A), COX2 (B), eNOS (C) and CD31 (D). The expressions of VEFG, COX2, eNOS and CD31 were significantly decreased in the OVX mice compared to the sham mice. These changes of VEGF signaling were restored in OVX mice by BSHX formula treatment. Scale bars: 1000 µm. *P < 0.05, **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X