Comparable clinical outcomes of culture-negative and culture-positive periprosthetic joint infections: a systematic review and meta-analysis

Li, Feng; Qiao, Yongjie; Zhang, Haoqiang; Cao, Guoding; Zhou, Shenghu

doi:10.1186/s13018-023-03692-x

Journal of Orthopaedic Surgery and Research

Table 1 The main characteristics and quality assessment results of the included studies

From: Comparable clinical outcomes of culture-negative and culture-positive periprosthetic joint infections: a systematic review and meta-analysis

Author	Year	Country	Study type	Study period	Follow-up (months)	Diagnostic criteria	Sample size	Joint involved		Surgical strategies				NOS scores
Author	Year	Country	Study type	Study period	Follow-up (months)	Diagnostic criteria	CN PJI/CP PJI	Hip	Knee	DAIR	One-stage	Two-stage	Others	NOS scores
van Eck [7]	2022	Netherlands	Retro	2014–2019	Minimum 12	ICM	60/299	228	131	359	0	0	0	8
Veerman [14]	2022	Netherlands	Retro	2012–2019	Minimum 24	IDSA	32/56	53	35	88	0	0	0	7
Xu [9]	2022	China	Retro	2012–2017	Mean 29.2	MSIS	22/48	n/a	n/a	21	13	36	0	8
Watanabe [16]	2021	Japan	Retro	2013–2019	Mean 51.5	ICM	27/82	79	24	21	10	66	12	9
Tirumala [17]	2021	USA	Retro	n/a	Minimum 36	ICM	46/103	59	90	149	0	0	0	7
Mulpur [10]	2021	India	Retro	2012–2018	Minimum 12	MSIS	27/53	0	80	80	0	0	0	8
Razii [15]	2021	UK	Retro	2006–2016	Mean 84	MSIS	16/68	84	0	0	84	0	0	6
Theil [18]	2020	Germany	Retro	2012–2016	Median 42	MSIS	153/51	93	111	0	0	204	0	8
Bongers [19]	2020	Netherlands	Retro	2003–2013	Minimum 24	MSIS	65/48	0	113	0	0	113	0	7
Ji [20]	2020	China	Retro	2009–2016	Mean 53.2	MSIS	51/192	104	139	0	243	0	0	8
Ji [21]	2019	China	Retro	2010–2016	Mean 58	MSIS	23/88	111	0	0	111	0	0	7
Xu [22]	2019	China	Retro	2012–2016	Minimum 12	MSIS	94/23	117	0	0	0	117	0	8
Wang [23]	2018	China	Retro	2003–2016	Median 68.5	MSIS	19/39	58	0	0	0	58	0	9
Kang [24]	2018	Korea	Retro	1996–2015	Mean 88.8	MSIS	15/70	85	0	0	0	85	0	8
Ibrahim [25]	2018	UK	Retro	2007–2012	Minimum 60	MSIS	50/50	100	0	0	0	100	0	9
Santoso [26]	2018	Indonesia	Retro	2010–2015	Mean 30.5	MSIS	27/57	84	0	0	0	84	0	9
Akgun [27]	2017	Germany	Retro	2013–2015	Mean 32.9	SSID	136/27	84	79	0	0	163	0	8
Li [28]	2017	China	Retro	2003–2014	Mean 59.5	MSIS	18/109	0	127	0	22	105	0	9
Bereza [39]	2016	Poland	Pro	n/a	Mean 32	MSIS	6/7	4	9	0	0	13	0	6
Tan [29]	2016	USA	Retro	1999–2013	Minimum 12	MSIS	234/33	81	186	0	0	267	0	9
Cha [30]	2015	Korea	Retro	1998–2011	Mean 30	MSIS	22/54	0	76	0	0	76	0	7
Triantafyllo-poulos [33]	2015	USA	Retro	2000–2013	Mean 79.7	MSIS	9/69	0	78	78	0	0	0	8
Kim [31]	2015	Korea	Retro	1991–2008	Mean 115.8	MSIS	51/140	0	191	109	0	82	0	9
Kim [32]	2015	Korea	Retro	2001–2008	Mean 120	MSIS	102/140	0	242	137	0	105	0	9
Nelson [34]	2014	USA	Retro	2010–2011	Mean 29.9	MSIS	18/18	7	29	0	0	36	0	6
Choi [35]	2013	USA	Retro	2000–2009	Mean 58	MSIS	40/135	78	97	54	0	110	11	9
Huang [36]	2012	USA	Retro	2000–2007	Mean 47	MSIS	48/295	n/a	n/a	97	5	238	3	9
Sorlí [38]	2012	Spain	Pro	2007–2008	Mean 12	n/a	44/11	17	37	0	0	55	0	6
Mortazavi [8]	2011	USA	Retro	1997–2007	Mean 45.6	n/a	40/77	0	117	0	0	117	0	6
Malekzadeh [37]	2010	Austria	Retro	1985–2000	Median 56	n/a	135/135	136	134	33	18	123	96	7

CN PJI culture-negative periprosthetic joint infection, CP PJI culture-positive periprosthetic joint infection, DAIR debridement, antibiotics and implant retention, NOS Newcastle–Ottawa scale, MSIS Musculoskeletal Infection Society, ICM International Consensus Meeting, IDSA Infectious Diseases Society of America, SSID Swiss Society of Infectious Diseases, n/a not acquire. retro retrospective, pro prospective

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ISSN: 1749-799X

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