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Table 2 SNV characteristics of the 20 most significant exon regions

From: Association between single nucleotide variants and severe chronic pain in older adult patients after lower extremity arthroplasty

CHROM

POS

ID

GeneName

P value

Xsquared

REF

ALT

Func

1

47282772

rs2297809

CYP4B1

0.001041944

13.73333333

C

T

Exonic

1

47280884

rs4646491

CYP4B1

0.001041944

13.73333333

C

T

Exonic

5

131607588

rs4877

PDLIM4

0.001272634

13.33333333

G

T

Exonic

2

107073501

rs62152530

RGPD3

0.001398075

10.20833333

C

T

Exonic

5

56177743

rs832582

MAP3K1

0.001525071

12.97142857

G

A

Exonic

14

57099859

rs1041316

TMEM260

0.001625041

12.84444444

G

A

Exonic

19

1827565

rs10415018

REXO1

0.001625041

12.84444444

A

G

Exonic

2

20824498

rs2305458

HS1BP3

0.001625041

12.84444444

C

T

Exonic

19

1819125

rs2396359

REXO1

0.003027555

11.6

T

C

Exonic

19

1811603

rs7250872

ATP8B3

0.003027555

11.6

C

T

Exonic

19

48198675

rs13346368

BICRA

0.003255945

11.45454545

A

G

Exonic

1

11014118

rs45537241

C1orf127

0.003255945

11.45454545

C

T

Exonic

1

11015165

rs75130475

C1orf127

0.003255945

11.45454545

A

G

Exonic

1

92327045

rs1805110

TGFBR3

0.003565811

0.003565811

G

A

Exonic

21

39671476

rs2230033

KCNJ15

0.003565811

0.003565811

G

A

Exonic

3

36897812

rs11712950

TRANK1

0.00386592

0.00386592

T

C

Exonic

14

21511497

rs1243469

RNASE7

0.004086771

0.004086771

C

T

Exonic

14

21511458

rs1243469

RNASE7

0.004086771

0.004086771

G

C

Exonic

11

104877927

rs507879

CASP5

0.004086771

0.004086771

T

C

Exonic

4

103611845

rs227368

MANBA

0.004185243

0.004185243

C

T

Exonic

  1. Binary logistic regression analysis was used to evaluate the correlation between each SNP loci and the risk of chronic pain in patients after lower extremity arthroplasty. P < 0.05 was regarded as statistically significant
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X