Fig. 5From: Specificity protein 1-mediated ACSL4 transcription promoted the osteoarthritis progression through suppressing the ferroptosis of chondrocytesAcsl4 knockdown neutralized the roles of IL-1β in the levels of ferroptosis-related genes. After IL-1β and si-Acsl4 treatment in the HCCs, the mRNA levels of Col2a1 (A), Acan (B), Mmp13 (C), Gpx4 (D) and Tfr1 E were determined by RT-qPCR assay. (F) The cell death was analyzed by PI stainingBack to article page