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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Bone marrow mesenchymal stem cell-derived exosomal microRNA-382 promotes osteogenesis in osteoblast via regulation of SLIT2

Fig. 2

Extraction and identification of exosomes from hBMSCs. A. Representative electron microscopy image of hBMSC-sEV from OP patients and normal persons. Bar: 100 nm. The EV particle size and concentration were measured by nanoparticle tracking analysis (NTA). B Western blotting analysis of markers (CD63, TSG101, HSP70) in hBMSC-sEV from OP patients and normal persons. C Heatmap and D volcano plots of DEGs analysis of miRNA between hBMSC-derived small EVs from OP patients and normal persons. Statistical evaluation was performed using one-way ANOVA. Mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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