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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: LncRNA HAGLR silencing inhibits IL-1β-induced chondrocytes inflammatory injury via miR-130a-3p/JAK1 axis

Fig. 4

Effects of lncRNA HAGLR-siRNA on IL-1β induced CHON-001 cells viability, LDH release and apoptosis. Expression of lncRNA HAGLR (A) and miR-130a-3p (B) were determined using qRT-PCR. C MTT assay of cell viability. D Analysis of LDH release. E Cell apoptosis were assessed by flow cytometry analysis. F Quantification of apoptotic cells. G Protein expression of cleaved-Caspase3. H Quantization of Caspase3 expression. **P < 0.01 versus Control; ##P < 0.01 versus IL-1β + control-siRNA; &&P < 0.01 versus IL-1β + HAGLR-siRNA + inhibitor control

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X