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Table 3 Effect of P-15 peptide on proliferation activity of IL-1β-induced chondrocytes (χ ± SD)

From: P-15 promotes chondrocyte proliferation in osteoarthritis by regulating SFPQ to target the Akt-RUNX2 axis

Groups

Cell activity (450 nm)

F

P

24 hpi

48 hpi

72 hpi

Control

0.515175 ± 0.01389

0.923625 ± 0.02226 a

1.496300 ± 0.02120 a, b

236.3

0.000

IL-1β

0.331750 ± 0.01367

0.391350 ± 0.01942 a

0.428000 ± 0.02833 a, b

116.8

0.000

IL-1β + P-15_L

0.467750 ± 0.01197

0.786100 ± 0.01709 a

1.091250 ± 0.04127 a, b

213.0

0.000

IL-1β + P-15_M

0.414675 ± 0.00792

0.641000 ± 0.03437 a

0.835100 ± 0.02137 a, b

175.1

0.000

IL-1β + P-15_H

0.368775 ± 0.01398

0.509200 ± 0.01550 a

0.597325 ± 0.01113 a, b

146.9

0.000

  1. Compared with 24 hpi, a, P < 0.05; compared with 48 hpi, b, P < 0.05