Fig. 1From: Sexual dimorphism in reactive oxygen species production and a role for integrin α1β1 in estrogen receptor α and β expression in articular cartilageRepresentative 2-D projections of summed fluorescence throughout a Z-stack of ex vivo chondrocytes stained with calcein (live cell dye) and dihydroethidium (that reacts with a variety of ROS to form 2-hydroxyethidium) and the two images merged (A). Images taken from a medial femoral condyle of a male wild-type mouse. Mean intensity (arbitrary units) of 2-hydroxyethidium in femoral chondrocytes from the medial and lateral condyles of male and female wild-type and itga1-null mice (B). Data points are means (N = 3 femora, n = 90 cells) ± 95% CI. Genotype effect dashed bracket, sex effect dotted bracket and compartment effect solid bracket, p < 0.001 (a)Back to article page