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Table 4 Clinical outcome of the study population stratified by lumbar interbody fusion types

From: Comparison of radiographic and clinical outcomes between ALIF, OLIF, and TLIF over 2-year follow-up: a comparative study

HRQoL

Overall (n = 348)

Group

p Value

ALIF (n = 69)

OLIF (n = 101)

TLIF (n = 178)

ODI

Pre-OP

54.8 ± 11.9

52.1 ± 14.9

55.2 ± 9.8

55.6 ± 11.6

0.11

(53.5–56)

(48.5–55.7)

(53.2–57.1)

(53.8–57.3)

1 M

47.5 ± 10.2

44.8 ± 11.6

47.8 ± 9.8

48.3 ± 9.8

0.02*

(46.4–48.5)

(42.1–47.6)

(45.9–49.8)

(46.8–49.7)

3 M

38.8 ± 12.4

34.6 ± 13

38.8 ± 12.4

40.4 ± 11.8

 < 0.01**

(37.5–40.1)

(31.5–37.8)

(36.3–41.2)

(38.6–42.1)

6 M

32.4 ± 15

26.5 ± 16.3

31.8 ± 14.8

35 ± 13.9

 < 0.01**

(30.8–33.9)

(22.6–30.4)

(28.8–34.7)

(32.9–37)

1 Y

28.2 ± 16.7

22.2 ± 17.2

27.2 ± 16.8

31 ± 15.8

 < 0.01**

(26.4–29.9)

(18–26.3)

(23.9–30.6)

(28.7–33.3)

2 Y

26.7 ± 17.8

20.8 ± 17.8

27.4 ± 18.6

28.6 ± 16.9

 < 0.01**

(24.8–28.6)

(16.5–25)

(23.7–31.1)

(26.1–31.1)

p value (2 Y-pre)

 < 0.01**

 < 0.01**

 < 0.01**

 < 0.01**

 

EQ-5D

Pre-OP

0.96 ± 0.09

0.94 ± 0.13

0.97 ± 0.06

0.97 ± 0.08

0.06

(0.95–0.97)

(0.91–0.97)

(0.96–0.98)

(0.96–0.98)

1 M

0.76 ± 0.09

0.73 ± 0.12

0.77 ± 0.07

0.77 ± 0.08

 < 0.01**

(0.75–0.77)

(0.7–0.76)

(0.76–0.79)

(0.75–0.78)

3 M

0.7 ± 0.13

0.66 ± 0.14

0.7 ± 0.13

0.72 ± 0.13

 < 0.01**

(0.69–0.72)

(0.63–0.69)

(0.67–0.72)

(0.7–0.74)

6 M

0.64 ± 0.16

0.59 ± 0.17

0.65 ± 0.15

0.67 ± 0.16

 < 0.01**

(0.63–0.66)

(0.54–0.63)

(0.61–0.68)

(0.64–0.69)

1 Y

0.62 ± 0.17

0.57 ± 0.18

0.62 ± 0.17

0.64 ± 0.17

0.02*

(0.6–0.64)

(0.53–0.62)

(0.58–0.65)

(0.61–0.66)

2 Y

0.62 ± 0.17

0.55 ± 0.17

0.66 ± 0.18

0.62 ± 0.17

 < 0.01**

(0.6–0.64)

(0.51–0.59)

(0.63–0.7)

(0.6–0.65)

p value (2 Y-pre)

 < 0.01**

 < 0.01**

 < 0.01**

 < 0.01**

 

VAS-Total

Pre-OP

8 ± 1.5

8.2 ± 1.7

7.8 ± 1.4

8.1 ± 1.4

0.16

(7.9–8.2)

(7.8–8.6)

(7.6–8.1)

(7.9–8.3)

1 M

3.9 ± 1.6

3.8 ± 1.7

4 ± 1.6

3.8 ± 1.6

0.41

(3.7–4.1)

(3.4–4.2)

(3.7–4.3)

(3.6–4.1)

3 M

3.3 ± 1.8

3.1 ± 1.8

3.3 ± 1.8

3.3 ± 1.8

0.32

(3.1–3.5)

(2.6–3.5)

(2.9–3.6)

(3.1–3.6)

6 M

2.9 ± 2

2.7 ± 2

2.8 ± 1.9

3.1 ± 2

0.22

(2.7–3.1)

(2.2–3.2)

(2.4–3.1)

(2.8–3.4)

1 Y

2.7 ± 2.1

2.6 ± 2.2

2.6 ± 2.3

2.9 ± 2

0.42

(2.5–3)

(2–3.1)

(2.2–3.1)

(2.6–3.2)

2 Y

2.8 ± 2.3

2.4 ± 2.2

3 ± 2.5

2.7 ± 2.2

0.34

(2.5–3)

(1.9–2.9)

(2.5–3.5)

(2.4–3.1)

p value (2 Y-pre)

 < 0.01**

 < 0.01**

 < 0.01**

 < 0.01**

 

VAS-Back

Pre-OP

7.1 ± 2.7

7.4 ± 2.6

6.9 ± 2.8

7.1 ± 2.6

0.47

(6.8–7.4)

(6.8–8)

(6.3–7.4)

(6.7–7.5)

1 M

3.2 ± 1.9

3 ± 1.9

3.5 ± 2

3.2 ± 1.8

0.11

(3–3.4)

(2.6–3.5)

(3.1–3.9)

(2.9–3.4)

3 M

2.7 ± 1.8

2.7 ± 2

2.7 ± 1.6

2.7 ± 1.9

0.89

(2.5–2.9)

(2.3–3.2)

(2.3–3)

(2.4–3)

6 M

2.4 ± 2

2.1 ± 2

2.2 ± 1.7

2.7 ± 2.1

0.17

(2.2–2.6)

(1.6–2.6)

(1.9–2.5)

(2.3–3)

1 Y

2.3 ± 2

2.1 ± 2

2.1 ± 2

2.5 ± 2

0.25

(2.1–2.5)

(1.6–2.6)

(1.7–2.5)

(2.2–2.8)

2 Y

2.4 ± 2.3

2.1 ± 2.1

2.6 ± 2.4

2.5 ± 2.3

0.42

(2.2–2.7)

(1.6–2.6)

(2.1–3.1)

(2.1–2.8)

p value (2 Y-pre)

 < 0.01**

 < 0.01**

 < 0.01**

 < 0.01**

 

VAS-Leg

Pre-OP

7.2 ± 2.7

6.7 ± 3

6.8 ± 3

7.5 ± 2.4

0.08

(6.9–7.4)

(6–7.4)

(6.2–7.4)

(7.2–7.9)

1 M

2.7 ± 2.4

2.6 ± 2.4

2.5 ± 2.4

2.9 ± 2.4

0.29

(2.5–3)

(2–3.2)

(2–2.9)

(2.6–3.3)

3 M

2 ± 2.3

1.8 ± 2.4

1.8 ± 2.4

2.2 ± 2.2

0.16

(1.8–2.3)

(1.3–2.4)

(1.4–2.3)

(1.9–2.5)

6 M

1.6 ± 2.2

1.6 ± 2.2

1.4 ± 2.2

1.7 ± 2.2

0.62

(1.4–1.8)

(1.1–2.2)

(1–1.8)

(1.4–2)

1 Y

1.4 ± 2.3

1.3 ± 2.1

1.2 ± 2.4

1.6 ± 2.3

0.33

(1.2–1.7)

(0.8–1.8)

(0.8–1.7)

(1.3–2)

2 Y

1.3 ± 2.3

1.3 ± 2.2

1.2 ± 2.6

1.3 ± 2.2

0.55

(1–1.5)

(0.8–1.9)

(0.7–1.8)

(1–1.6)

p value (2 Y-pre)

 < 0.01**

 < 0.01**

 < 0.01**

 < 0.01**

 
  1. p value < 0.05 was consider statistically significant. Values expressed as the mean ± standard deviation and 95 confidence interval range in the brackets. p < 0.05*, p < 0.01**
  2. ALIF Anterior lumbar interbody fusion, OLIF Oblique lumbar interbody fusion, TLIF Transforaminal lumbar interbody fusion, HRQoL Health-related quality of life, ODI Oswestry disability index, EQ-5D EuroQol-5-dimension score, VAS-Total VAS of pain in total, VAS-Leg VAS of pain in leg, VAS-Back VAS of pain in back, M Month, Y Year
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X