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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: LINC00313 promotes the proliferation and inhibits the apoptosis of chondrocytes via regulating miR-525-5p/GDF5 axis

Fig. 4

Overexpression of miR-525-5p reversed the effect of LINC00313 in C28/I2 cells. A: Transfection effect of miR-525-5p inhibitor and overexpression miR-525-5p on C28/I2 cells. B–C: Overexpression of miR-525-5p reduced the effect of LINC00313 on C28/I2 cell viability. D–F: Overexpression of miR-525-5p reduced the effect of LINC00313 on the expression of IL-1β, IL-6 and TNF-α in C28/I2 cells. G–K: Overexpression of miR-525-5p reversed the effect of LINC00313 on C28/I2 cell apoptosis. *P < 0.05, **P < 0.01, ***P < 0.001; #P < 0.05, ##P < 0.01, ###P < 0.01

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