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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Icariin-conditioned serum combined with chitosan attenuates cartilage injury in rabbit knees with osteochondral defect

Fig. 3

ICS-CSSH improved the repairment of osteochondral defect and subchondral bone in vivo through histologic observation. A H&E staining in femoral condyle of rabbit in NS, CSSH, ICS and ICS-CSSH groups. Scale bar, 100 μm. B Safranin O staining in femoral condyle of rabbit in NS, CSSH, ICS and ICS-CSSH groups. Scale bar, 100 μm. C Modified Mankin’s score for the evaluation of H&E staining in NS, CSSH, ICS and ICS-CSSH groups (n = 6, mean ± SEM). **P < 0.01, ***P < 0.001 versus indicated groups. D Calculation of Osteoarthritis Research Society International (OARSI) scores in NS, CSSH, ICS and ICS-CSSH groups (n = 6, mean ± SEM). **P < 0.01, ***P < 0.001 versus indicated groups

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X