Table 3 Results of adverse events*

Abaloparatide versus Placebo

Any adverse event

9

3443

OR 1.09 [0.91, 1.31]

0%

P = 0.33

0.6812

Moderate

Serious adverse events

9

3443

OR 0.91 [0.70, 1.19]

0%

P = 0.49

0.4012

Moderate

Deaths

2

2778

OR 0.47 [0.13, 1.68]

0%

P = 0.24

N/A

Moderate

Nausea

5

2044

OR 2.61 [1.73, 3.95]

0%

P < 0.00001

0.1555

High

Hypercalciuria

8

2314

OR 1.11 [0.83, 1.48]

0%

P = 0.47

0.0038

Very Low

Hypercalcemia

7

665

OR 1.30 [0.58, 2.91]

0%

P = 0.52

0.4974

Moderate

Headache

5

2044

OR 1.11 [0.79, 1.55]

0%

P = 0.55

0.0668

Moderate

Back pain

9

3443

OR 1.06 [0.81, 1.37]

0%

P = 0.69

0.0083

Very Low

Palpitations

5

2041

OR 12.54 [4.50, 34.93]

0%

P < 0.00001

0.1316

High

Abaloparatide versus Teriparatide

Any adverse event

4

1908

OR 0.98 [0.75, 1.28]

0%

P = 0.87

0.0612

Moderate

Serious adverse events

3

1820

OR 0.99 [0.72, 1.37]

0%

P = 0.96

0.0125

Low

Deaths

2

2775

OR 0.64 [0.17, 2.46]

0%

P = 0.52

N/A

Low

Hypercalciuria

4

1908

OR 0.85 [0.64, 1.13]

0%

P = 0.27

0.1387

Moderate

Hypercalcemia

3

266

OR 0.49 [0.18, 1.35]

0%

P = 0.17

0.1056

High

Back pain

4

1908

OR 1.36 [0.94, 1.95]

5%

P = 0.10

0.2971

Moderate