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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: MiR-218-5p-dependent SOCS3 downregulation increases osteoblast differentiation inpostmenopausal osteoporosis

Fig. 1

SOCS3 silencing promotes BMSC osteogenesis. A The SOCS3 level in rat BMSCs after transfection of sh-SOCS3 was detected by RT-qPCR. B Alizarin red staining was used to evaluate the osteogenesis efficiency of BMSCs after Dex treatment or Dex treatment in combination with sh-SOCS3. C ALP activity was measured in the control, Dex, and Dex + sh-SOCS3 groups. D RT-qPCR was used to detect the mRNA expression of osteogenesis markers (ALP, OPN, OCN, COL1) in BMSCs after the indicated treatments. ***p < 0.001

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