Table 2 Overall study characteristics
Author | Time to full weight bearing (months) | Length of endoprosthetic stem (mm) | Adjuvant chemotherapy | Adjuvant radiotherapy | Non-union, aseptic loosening | Implant breakage | Fracture | Infection | Mechanical survival | Oncological outcome | MSTS score | Follow-up (months) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Christ et al. [11] | NR | 68 | NR | NR | Aseptic loosening (14%) | 21% (screw breakage: 7%, fractures of the taper at the modular junction between the custom stem and the rest of the modular prosthesis: 14%) | 0 | 7% | NR | Local recurrence (0) | Mean: 24 (range, 16–30) | Mean: 72 |
Hindiskere et al. [2] | Median: 7 (range, 6–9) | Median: 135 (range, 120–165) | 29% | NR | Non-union (0), aseptic loosening (21%) | 7% | 0 | 7% | Mechanical survival at 7 years: 80% | CDF (13) DOD (1) | Median: 27 (range, 22–30) | Median: 49 |
Bernthal et al. [12] | NR | NR | 14% | NR | Aseptic loosening (8%) | 11% (a fatigue fracture of the stem through cross-pin holes) | 0 | 17% | Mechanical survival at 5 years: 82%, 10 years: 77%, 15 years: 77% | Local recurrence (2) | NR | Median: 132 |
Stevenson et al. [5] | NR | Mean: 79 (range, 34–100) | NR | 15% | Aseptic loosening (0) | 8% | 0 | 8% | Mechanical survival at 10 years: 70% | Local recurrence (0) | NR | Mean: 84 (range, 12–204) |
Calvert et al. [16] | 1.5 months non-weight bearing | NR | 3% | 0 | Aseptic loosening (14%) | 0 | 2% | 12% | Mechanical survival at 2 years: 68% | NR | NR | Mean: 68 (range, 31–113) |
Dieckmann et al. [13] | NR | Mean: 77 (range, 45–130) | NR | NR | Aseptic loosening (13%) | 7% (screw breakage) | 7% | 7% | NR | CDF (8), AWD (2), DOD (5) | Mean: 23 (range, 9–28) | Mean: 47 (range, 5–95) |
Cobb et al. [14] | 1.5 | Mean: 60 (range, 40–70) (Length of plate) | NR | NR | Aseptic loosening (17%) | 0 | 0 | 0 | NR | CDF (5), DOD (1) | Mean: 28 (range, 27–30) | Mean: 67 (range, 11–93) |
Cannon et al. [15] | NR | NR | NR | NR | Aseptic loosening (5%) | 5% (a fatigue fracture of a Morse taper trunnion of a custom-casted component) | 0 | 0 | NR | NR | NR | Median: 57 (range, 25–182) |