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Table 1 Overall study characteristics

From: Megaprosthetic reconstruction of the distal femur with a short residual proximal femur following bone tumor resection: a systematic review

Author

Year

Type of study

Period investigated

Number of patients

Age (years)

Histology

Indication

Type of reconstruction

Cement fixation

Porous coating

Christ et al. [11]

2021

SR

2002 to 2018

14

Mean: 36

Osteosarcoma (10), Ewing sarcoma (2), Pleomorphic sarcoma (1), and GCTB (1)

The remaining short proximal femur was used in 24%, and 8/14 retained ≤ 20% of their femur

Short-stemmed endoprostheses with custom cross-pin and extra-cortical plates fixation

None

Yes

Hindiskere et al. [2]

2021

SR

2008 to 2018

14

Median: 14 (range, 7–18)

Osteosarcoma (14)

Length of proximal femur remaining after tumor resection was < 12 cm

Allograft prosthetic composite

None: 5, Only in allograft: 3, In allograft and host bone: 6

NA

Bernthal et al. [12]

2019

SR

1980 to 2017

36

Mean: 33

Osteosarcoma (5), Chondrosarcoma (4)

(1) Projected stem length of ≤ 9 cm; (2) < 2 cm of residual diaphyseal bone; or (3) early (within two years) aseptic loosening of a long stem due to rotational instability

Short-stemmed endoprostheses with custom cross-pin fixation

All

No

Stevenson et al. [5]

2017

SR

1998 to 2013

13

Mean: 26

NR

A short stem was defined as < 100 mm

Short-stemmed endoprostheses with extra-cortical plates

None

Yes

Calvert et al. [16]

2014

MR

NR

37

Mean: 21

Osteosarcoma (47)

Patients with a short proximal femur remaining after tumor resection and unable to insert a standard-length stem

Compressive osseointegration

None

Yes

Dieckmann et al. [13]

2014

SR

2003 to 2012

15

Mean: 33 (range, 11–73)

Osteosarcoma (9), Ewing sarcoma (4), Chondrosarcoma (2), and Myxofibrosarcoma (1)

Remaining proximal femur after tumor resection should be at least 40 mm

Short-stemmed endoprostheses with custom cross-pin fixation

None

Yes

Cobb et al. [14]

2005

SR

1987 to 1988

6

Mean: 32 (range, 9–72)

Osteosarcoma (4), Ewing sarcoma (1), and GCTB (1)

The remaining distal end of the femur after tumor resection was within 50 mm of the lesser trochanter

Triplate fixation

None

Yes

Cannon et al. [15]

2003

SR

1988 to 2001

22

Range: 6–68

Osteosarcoma (6), Ewing sarcoma (3), Chondrosarcoma (2), and MFH (1)

Patients with short proximal femur remaining after tumor resection

Short-stemmed endoprostheses with custom cross-pin fixation

All

No

  1. SR single institutional non-randomized retrospective study; MR multi-institutional non-randomized retrospective study; GCTB giant cell bone tumor; MFH malignant fibrous histiocytoma; NA not applicable; NR not reported