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Fig. 9 | Journal of Orthopaedic Surgery and Research

Fig. 9

From: Deciphering the protective effect of Buzhong Yiqi Decoction on osteoporotic fracture through network pharmacology and experimental validation

Fig. 9

BZYQD suppressed the activation of NF-κB and activated Nrf2/MAPK signaling pathways. A TNF-α, B IL-6, C IL-1β, and D IL-10 (n = 6). BZYQD upregulated the E GSH and F SOD and downregulated the G MDA (n = 6). H Representative Western blot bands and the results of semi-quantitative analysis of I Nrf-2, J HO-1, K p-IKBα/IKBα, and L p-NF-κB/NF-κB (n = 3). M The Western blot bands and the results of semi-quantitative analysis of N p-ERK1/2/ERK1/2 and O p-P38 MAPK/P38 MAPK (n = 3). **p < 0.01, versus control group; #p < 0.05, ##p < 0.01, versus model group

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