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Table 3 Most significant enrichment of the top 20 GO term entries according to FDR value at postoperative 6 months

From: Continuous dynamic identification of key genes and molecular signaling pathways of periosteum in guided bone self-generation in swine model

Category

GO.ID

Term

Up

Down

DEG

Total

P value

FDR

CC

GO:0005576

Extracellular region

6

120

126

1457

5.54376E−31

3.58792E−27

CC

GO:0005615

Extracellular space

5

93

98

1003

9.09151E−28

2.94201E−24

CC

GO:0031012

Extracellular matrix

2

45

47

280

4.99476E−23

1.07754E−19

BP

GO:0030198

Extracellular matrix organization

3

29

32

206

2.16642E−14

2.91876E−11

BP

GO:0007166

Cell surface receptor signaling pathway

10

106

116

1889

2.25491E−14

2.91876E−11

BP

GO:0043062

Extracellular structure organization

3

29

32

208

2.86403E−14

3.08933E−11

CC

GO:0062023

Collagen-containing extracellular matrix

1

26

27

157

5.69719E−14

4.94137E−11

BP

GO:0048731

System development

22

136

158

2997

6.10799E−14

4.94137E−11

BP

GO:0007275

Multicellular organism development

22

146

168

3275

7.24107E−14

5.17343E−11

CC

GO:0005581

Collagen trimer

1

16

17

54

7.99355E−14

5.17343E−11

BP

GO:0009653

Anatomical structure morphogenesis

15

96

111

1821

1.63518E−13

9.62078E−11

BP

GO:0009888

Tissue development

15

69

84

1244

1.53016E−12

8.25266E−10

BP

GO:0048646

Anatomical structure formation involved in morphogenesis

7

53

60

766

1.04821E−11

4.9289E−09

BP

GO:0048856

Anatomical structure development

22

154

176

3691

1.0662E−11

4.9289E−09

BP

GO:0032502

Developmental process

23

163

186

3988

1.33031E−11

5.73987E−09

BP

GO:0048513

Animal organ development

16

101

117

2138

4.21883E−11

1.70652E−08

MF

GO:0005539

Glycosaminoglycan binding

1

21

22

139

5.78714E−11

2.2032E−08

MF

GO:0044877

Protein-containing complex binding

4

50

54

730

1.05977E−10

3.64587E−08

BP

GO:0051239

Regulation of multicellular organismal process

9

100

109

1964

1.07033E−10

3.64587E−08

BP

GO:0030199

Collagen fibril organization

1

12

13

41

1.21547E−10

3.93325E−08