Continuous dynamic identification of key genes and molecular signaling pathways of periosteum in guided bone self-generation in swine model

Table 2 Most significant enrichment of the top 20 GO term entries according to FDR value at postoperative 5 weeks

Category	GO.ID	Term	Up	Down	DEG	Total	P value	FDR
CC	GO:0005739	Mitochondrion	281	19	300	1111	1.93367E−68	1.88726E−64
CC	GO:0005737	Cytoplasm	689	301	990	7284	1.22918E−56	5.99839E−53
BP	GO:0055114	Oxidation–reduction process	177	29	206	838	2.26224E−38	7.35983E−35
BP	GO:0006091	Generation of precursor metabolites and energy	97	9	106	311	1.18895E−32	2.90104E−29
BP	GO:0015980	Energy derivation by oxidation of organic compounds	74	5	79	186	3.79835E−32	7.41437E−29
CC	GO:0031966	Mitochondrial membrane	106	8	114	370	4.54542E−31	7.39388E−28
BP	GO:0044281	Small molecule metabolic process	198	46	244	1230	1.74148E−29	2.42812E−26
CC	GO:0005740	Mitochondrial envelope	110	8	118	410	4.27028E−29	5.20974E−26
BP	GO:0045333	Cellular respiration	59	1	60	127	9.27649E−28	9.73815E−25
CC	GO:0005743	Mitochondrial inner membrane	82	5	87	253	9.97761E−28	9.73815E−25
MF	GO:0016491	Oxidoreductase activity	135	25	160	685	4.57839E−27	4.06228E−24
CC	GO:0019866	Organelle inner membrane	85	5	90	291	7.56808E−25	6.15537E−22
CC	GO:1990204	Oxidoreductase complex	47	2	49	104	4.06519E−23	3.05202E−20
BP	GO:0006082	Organic acid metabolic process	118	30	148	663	5.92202E−23	4.12849E−20
BP	GO:0043436	Oxoacid metabolic process	116	29	145	647	1.12659E−22	7.33036E−20
BP	GO:0030029	Actin filament-based process	67	62	129	543	1.32829E−22	8.10257E−20
CC	GO:0030016	Myofibril	44	8	52	121	3.77096E−22	2.16498E−19
CC	GO:0098798	Mitochondrial protein complex	72	2	74	231	1.20695E−21	6.54435E−19
CC	GO:0043292	Contractile fiber	45	8	53	129	1.88861E−21	9.70148E−19
CC	GO:0005759	Mitochondrial matrix	65	1	66	193	3.63184E−21	1.77234E−18

ISSN: 1749-799X