Continuous dynamic identification of key genes and molecular signaling pathways of periosteum in guided bone self-generation in swine model

Table 1 Most significant enrichment of the top 20 GO term entries according to FDR value at postoperative 1 week

Category	GO.ID	Term	Up	Down	DEG	Total	P value	FDR
BP	GO:0055114	Oxidation–reduction process	235	52	287	838	1.95069E−34	2.38901E−30
CC	GO:0005737	Cytoplasm	975	554	1529	7284	1.95363E−33	1.1963E−29
CC	GO:0030016	Myofibril	73	7	80	121	3.20043E−33	1.30652E−29
CC	GO:0043292	Contractile fiber	74	7	81	129	3.09568E−31	9.4782E−28
CC	GO:0030017	Sarcomere	66	6	72	107	8.92585E−31	2.1863E−27
BP	GO:0044281	Small molecule metabolic process	280	87	367	1230	6.62519E−30	1.35231E−26
BP	GO:0015980	Energy derivation by oxidation of organic compounds	90	6	96	186	6.57423E−27	1.15021E−23
BP	GO:0048856	Anatomical structure development	482	375	857	3691	1.54117E−26	2.35934E−23
BP	GO:0006082	Organic acid metabolic process	174	51	225	663	2.18282E-26	2.85419E-23
BP	GO:0043436	Oxoacid metabolic process	172	49	221	647	2.33052E−26	2.85419E−23
MF	GO:0016491	Oxidoreductase activity	182	47	229	685	4.10707E−26	4.57267E−23
BP	GO:0032502	Developmental process	511	400	911	3988	5.37969E−26	5.49043E−23
CC	GO:0005739	Mitochondrion	287	37	324	1111	2.43081E−25	2.29001E−22
MF	GO:0003779	Actin binding	81	53	134	326	8.40912E−25	7.35617E−22
BP	GO:0006091	Generation of precursor metabolites and energy	123	7	130	311	1.0409E−24	8.49862E−22
BP	GO:0045333	Cellular respiration	69	4	73	127	1.5503E−24	1.18666E−21
CC	GO:0031674	I band	49	4	53	76	3.73754E−24	2.69256E−21
BP	GO:0019752	Carboxylic acid metabolic process	164	42	206	610	6.64057E−24	4.51817E−21
BP	GO:0048731	System development	389	318	707	2997	4.92627E−23	3.17537E−20
BP	GO:0009653	Anatomical structure morphogenesis	250	221	471	1821	5.78295E−23	3.54119E−20

ISSN: 1749-799X