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Table 1 Baseline characteristics of the included studies

From: Correlation between C-reactive protein and postoperative mortality in patients undergoing hip fracture surgery: a meta-analysis

Author [Year]

Country

Design

Model

Sample size

Age (years) Mean ± SD/median (min–max)

Women (n, %)

Endpoint

Long-term mortality (≥ 6 months)

Azevedo [2017]

Brazil

Prospective cohort

Preoperative CRP

D: 17

D: 82.9 ± 8.9

D: 7, 41.2%

6-month mortality

    

S: 58

S: 78.4 ± 7.2

S: 42, 72.4%

 

Capkin [2021]

Turkey

Retrospective cohort

Preoperative CRP

D: 58

78.74 ± 6.88

D: 25, 36.7%

1-year mortality

    

S: 196

 

S: 124, 63.3%

 

Choi [2021]

South Korea

Retrospective cohort

Postoperative CRP

D: 43

D: 82.5 ± 5.8

D: 27, 62.8%

1-year mortality

    

S: 220

S: 80.0 ± 7.2

S: 163, 74.1%

 

Colino [2018]

Spain

Prospective cohort

Preoperative CRP

D: 118

D: 88.1 ± 6.5

D: 86, 76.9%

1-year mortality

    

S: 391

S: 84.8 ± 6.9

S: 317, 81.1%

 

Gulin [2015]

Croatia

Prospective cohort

Preoperative CRP

D: 67

D: 86.0 (82.0–89.0)

D: 47, 70.1%

1-year mortality

    

S: 169

S: 79.0 (73.0–85.3)

S: 130, 76.9%

 

Gumieiro [2013]

Brazil

Prospective cohort

Preoperative CRP

D: 11

D: 82.5 ± 6.8

D: 8, 72.7%

6-month mortality

    

S: 71

S: 80.0 ± 7.39

S: 54, 76.1%

 

Kim [2016]

Korea

Retrospective cohort

Preoperative CRP

D: 109

D: 80.2 ± 8.0

D: 73, 67%

1-year mortality

   

Postoperative CRP

S: 663

S: 79.3 ± 7.1

S: 507, 76.5%

 

McLeod [2022]

United Kingdom

Retrospective cohort

Preoperative CRP

D: 94

D: 80.9 ± 9.6

D: 70, 74.5%

1-year mortality

    

S: 235

S: 82.5 ± 10.0

S: 174, 74%

 

Sedlář [2015]

Czechia

Prospective cohort

Preoperative CRP

D: 64

D: 82 ± 8

D: 47, 73.4%

5-year mortality

   

Postoperative CRP

S: 40

S: 76 ± 8

S: 28, 70%

 

Zhou [2021]

China

Retrospective cohort

Postoperative CRP

D: 26

N/A

D: 10, 38.5%

1-year mortality

    

S: 98

 

S: 63, 64.3%

 

Short-term mortality (≤ 30 days)

Bae [2021]

Korea

Retrospective cohort

Preoperative CRP

D: 19

D: 82.5 ± 10.1

D: 9, 47.4%

Intrahospital mortality

    

S: 443

S: 74.0 ± 16.3

S: 311, 70.2%

 

Balta [2022]

Turkey

Retrospective cohort

Preoperative CRP

D: 30

83.09 ± 8.52

D: 19, 63.3%

30‑day mortality

    

S: 135

 

S: 76, 56.3%

 

Çiçek [2021]

Turkey

Retrospective cohort

Preoperative CRP

D: 30

D: 84.4 ± 6.2

D: 22, 73.3%

Intrahospital mortality

    

S: 247

S: 81.7 ± 7.5

S: 181, 73.3%

 

Niessen [2018]

Belgium

Retrospective cohort

Preoperative CRP

D: 16

D: 85.3 ± 9.1

N/A

Intrahospital mortality

    

S: 318

S: 83.6 ± 7.4

  
  1. CRP, C-reactive protein; D, death group; max, maximum; min, minimum; N/A, not available; S, survival group; SD, standard deviation
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X