Fig. 1From: Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the kneeEffect of bevacizumab on cartilage degradation in the presence and absence of interleukin (IL)-1β. Concentrations of markers in culture media were measured by enzyme-linked immunosorbent assay. A Matrix metalloproteinase (MMP)-2, B MMP-3, C MMP-9, D MMP-13, E tissue inhibitor of metalloproteinase (TIMP)-1, F TIMP-2, and G cartilage oligomeric matrix protein (COMP). Values are given as means and standard deviation. *P < 0.05 versus IL-1β(-)/bevacizumab 0 ng/ml and †P < 0.05 versus IL-1β(+)/bevacizumab 0 ng/mlBack to article page