Author | Year | Reference standard | Type of nuclear medicine methods | Injected dose (MBp) | Time between injection and image acquisition | Threshold |
---|---|---|---|---|---|---|
Paez, et al. | 2021 | biopsy or follow-up for at least 6Â months | PET/CT | NA | NA | Score 3 and 4 |
Segawa, et al. | 2021 | biology or clinical observation | PET/CT | up to 370Â MBq | 60Â min | 5.0 for SUVmax |
Brown, et al. | 2020 | microbiology assessment | PET/CT | 200Â MBq | 60Â min | NA |
Altini, et al. | 2020 | resolution or significant improvement of constitutional symptoms | PET/CT | 2.5–3 MBq/kg | 60 min | NA |
Frenkel, et al. | 2019 | clinical and bacteriological findings | PET/CT | 296–555 MBq | 60–90 min | NA |
Follenfant, et al. | 2019 | observation of pus surrounding the implant during a new surgery and/or the identification of a microorganism from cultures of bone tissue or blood | PET/CT | NA | 60Â min | NA |
Kouijzer, et al. | 2018 | IDSA guideline, imaging and clinical findings | PET/CT | 3.3Â MBq/kg | 60Â min | NA |
Yu, et al. | 2018 | bacterial cultures and outcomes after cessation or withholding of antibiotic therapy | PET/CT | 550Â MBq | 60Â min | NA |
Smids, et al. | 2017 | a microorganism was isolated and/or imaging follow-up showing response to antibiotic therapy | PET/CT | 200Â MBq | 60Â min | NA |
Fahnert, et al. | 2016 | histopathologic evaluation of surgery or biopsy specimens or clinical follow-up | PET | 4 MBq/kg; range, 149–410 MBq | 75 min (60–105 min) | SUVmax ratio of 2.1 |
Fuster, et al. | 2015 | micrological documentation in cultures of image-guided spinal puncture fluid or blood | PET/CT | 4.07Â MBq/kg | 60Â min | SUVmax ratio of 2.2 |
Skanjeti, et al. | 2012 | a long diagnostic work-up including spinal MRI, blood cultures or vertebral biopsy | PET | 222–370 MBq | 60 min | NA |
Seifen, et al. | 2012 | biopsy, blood culture and a one-year clinical follow-up | PET/CT | 4 MBq/kg; range, 253–493 MBq | 60 min | NA |
Ohtori, et al. | 2010 | symptoms, x-ray imaging, MRI, blood data, and results of biopsies from the first examination to final follow-up | PET | NA | NA | NA |
De Winter, et al. | 2003 | histopathology, microbiology and/or intraoperative visual assessment or minimum follow-up of 12 months | PET | 370 MBq | 60–90 min | NA |
Strumpe, et al. | 2002 | cultures from the bone biopsies or blood, clinical and laboratory findings | PET | 300–400 MBq | 30–40 min | NA |
Gratz, et al. | 2002 | biopsy, histology, culture, clinical and laboratory findings | PET | 296Â MBq | 60Â min | NA |
Schimitz, et al. | 2001 | histopathological examination | PET | 200–400 MBq | 45 min | NA |