Table 1 Main characteristics of the included studies
Author | Year | Region | Design | Blind (= 0 if NR, = 1 if Y) | Inclusion interval | Number of patients | Patients’ demographics (male/female) | Age, yrs | Type of infection | Number of infected patients |
|---|---|---|---|---|---|---|---|---|---|---|
Paez, et al. | 2021 | Austria | P | 1 | 2013.12–2017.12 | 44 | NA | NA | Postoperative spondylodiscitis | 30 |
Segawa, et al. | 2021 | Japan | R | 1 | 2008.12–2018.07 | 50 | 12/38 | 65.5 ± 17.4 | Postoperative spondylitis | 29 |
Brown, et al. | 2020 | UK | R | 0 | 2012–2017 | 49 | 16/33 | 33(17–70) | Postoperative spondylitis | 24 |
Altini, et al. | 2020 | Italy | R | 0 | 2013.04–2018.10 | 56 | 39/17 | 18–90 | Spondylodiscitis | 48 |
Frenkel, et al. | 2019 | Israel | R | 0 | 2011.01.01–2013.12.31 | 9 | 5/4 | 59.2 ± 16.4 | Postoperative hardware-related spondylitis | 5 |
Follenfant, et al. | 2019 | France | R | 1 | 2010.4–2018.7 | 44 | 22/22 | 25–75 | Postoperative hardware-related spondylitis | 22 |
Kouijzer, et al. | 2018 | Netherlands | P | 0 | 2015.11–2016.12 | 32 | 22/10 | 66.8(43–92) | Vertebral osteomyelitis | 20 |
Yu, et al. | 2018 | Canada | P | 1 | 2011–2015 | 149 | 94/55 | NA | Pyogenic spondylitis | 43 |
Smids, et al. | 2017 | Netherlands | R | 0 | 2006.01–2013.08 | 68 | 35/33 | NA | Spondylodiscitis | 49 |
Fahnert, et al. | 2016 | Germany | P | 1 | 2014.03–2015.08 | 28 | 10/18 | NA | Spondylodiscitis | 12 |
Fuster, et al. | 2015 | Spain | P | 1 | 2008.12–2012.02 | 26 | 14/12 | 59 ± 17 | Spondylodiscitis | 18 |
Skanjeti, et al. | 2012 | Italy | R | 0 | 2005.05–2010.04 | 24 | 13/11 | 56.9 ± 17.8 | Spondylodiscitis | 14 |
Seifen, et al. | 2012 | Austra | R | 1 | 2006.05–2010.10 | 38 | 20/18 | 67 ± 14 | Spondylodiscitis | 22 |
Ohtori, et al. | 2010 | Japan | P | 1 | NR | 18 | 14/4 | 66 ± 10.6 | Pyogenic spondylitis | 11 |
De Winter, et al. | 2003 | Belgium | P | 1 | 1999.02–2001.06 | 57 | 27/30 | 13–74 | Postoperative spondylitis | 15 |
Strumpe, et al. | 2002 | Switherland | P | 1 | 2000.05–2000.10 | 30 | 11/19 | 54(27–80) | Spondylodiscitis | 5 |
Gratz, et al. | 2002 | Germany | P | 1 | 1999.06–2000.12 | 16 | 9/7 | 59 (25–78) | Spondylitis | 12 |
Schimitz, et al. | 2001 | Germany | R | 1 | NR | 16 | 10/6 | 15–85 | Spondylodiscitis | 12 |