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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Correlation analysis of differentially expressed long non-coding RNA HOTAIR with PTEN/PI3K/AKT pathway and inflammation in patients with osteoarthritis and the effect of baicalin intervention

Fig. 3

The optimal stimulation concentration of PBMCs (3:1, 48 h), baicalin (50 ug/ml, 48 h), and si-lncRNA HOTAIR 2# was screened and lncRNA HOTAIR silencing facilitated the viability of OA-CHs. A PBMCs: OA-CHs screening of the optimal concentration. B Baicalin screening of the optimal concentration. C Screening of si-lncRNA HOTAIR. D Effect of lncRNA HOTAIR on the viability of OA-CHs was tested by CCK-8 assay. E LncRNA HOTAIR expression in OA-CHs was measured by RT-qPCR. PC, PBMCs: OA-CHs. pc, pcDNA3.1. All tests were repeated three times and results were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001

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