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Table 1 Comparison of HPOC versus titanium at 6- and 12-weeks follow-up (MD: mean difference)

From: Silica coated high performance oxide ceramics promote greater ossification than titanium implants: an in vivo study

Endpoint

6 weeks

12 weeks

Ceramic

Titanium

MD

P

Ceramic

Titanium

MD

P

Lateral

BIC (%)

3.0 ± 2.6

3.1 ± 3.9

− 0.1

0.5

2.8 ± 3.5

3.9 ± 3.7

− 1.0

0.3

OIC (%)

0.9 ± 1.7

0.0 ± 0.3

0.9

0.07

1.6 ± 2.1

0.4 ± 0.1

1.1

0.09

Distal

BIC (%)

13.2 ± 6.6

11.5 ± 2.1

1.7

0.2

13.9 ± 7.6

13.6 ± 7.7

0.2

0.5

OIC (%)

5.8 ± 2.5

1.6 ± 3.5

4.2

0.003

5.6 ± 4.6

5.0 ± 3.6

0.6

0.4

Medial

BIC (%)

5.6 ± 3.7

5.3 ± 3.1

0.2

0.4

8.2 ± 4.5

7.1 ± 3.5

1.1

0.3

OIC (%)

2.2 ± 1.5

− 0.3 ± 1.9

2.5

0.003

2.8 ± 2.3

1.4 ± 1.4

1.3

0.1

Proximal

BIC (%)

12.0 ± 6.2

10.8 ± 8.7

1.2

0.4

12.6 ± 6.2

11.6 ± 3.9

1.0

0.4

OIC (%)

5.0 ± 0.0

5.0 ± 0.9

0.0

1.0

5.0 ± 0.0

4.3 ± 2.4

0.7

0.1

Overall

BIC (%)

0.3 ± 0.1

0.3 ± 0.1

0.0

0.4

0.4 ± 0.1

0.3 ± 0.7

0.0

0.2

OIC (%)

13.9 ± 3.8

6.3 ± 1.7

7.6

0.0001

14.9 ± 7.7

11.1 ± 6.1

3.8

0.2

BIC (%)

0.6 ± 0.2

0.6 ± 0.6

0.0

0.5

0.3 ± 0.1

0.4 ± 0.4

0.0

1.0

  1. There is evidence of greater osteoid ossification in the ceramics group compared to the titanium cohort only at 6 weeks in the distal (P = 0.003), medial (P = 0.003) sides and at the overall level analysis (P = 0.0001)
  2. No other difference between the two implants has been evidenced in the other endpoints at both 6 or 12 weeks