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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology

Fig. 6

Quercetin significantly regulated the proliferation of osteoblasts through mediation of FOS. Osteoblasts were exposed to FAC, FAC + DMSO, FAC + si-FOS, FAC + oe-FOS or FAC + oe-FOS + quercetin. A The protein level of FOS in osteoblasts was assessed by western blot. B The expressions of p-mTOR, PI3K, AKT, p-AKT, p-PI3K, mTOR, Bax, Bcl-2 and Caspase-3 in osteoblasts were tested by western blot. C The viability of osteoblasts was assessed by CCK8 assay. D The apoptosis of osteoblasts was assessed by flow cytometry. *P < 0.05 compared to model. #P < 0.05 compared to oe-FOS

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