Fig. 6From: Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacologyQuercetin significantly regulated the proliferation of osteoblasts through mediation of FOS. Osteoblasts were exposed to FAC, FAC + DMSO, FAC + si-FOS, FAC + oe-FOS or FAC + oe-FOS + quercetin. A The protein level of FOS in osteoblasts was assessed by western blot. B The expressions of p-mTOR, PI3K, AKT, p-AKT, p-PI3K, mTOR, Bax, Bcl-2 and Caspase-3 in osteoblasts were tested by western blot. C The viability of osteoblasts was assessed by CCK8 assay. D The apoptosis of osteoblasts was assessed by flow cytometry. *P < 0.05 compared to model. #P < 0.05 compared to oe-FOSBack to article page