Fig. 1

PPI network. A Input the screened targets and disease targets into the Venn diagram creation software and obtain 117 common targets, which were applied as the targets of drugs. The following pathway enrichment analysis was performed. B, C To construct the PPI network, the frequent targets and diseases were entered into the String. D Topological analysis shows the top 20 key targets. E–J In this study, the core genes were screened by MCODE analysis. Import the PPI network into Cytoscape 3.8.0, open the MCODE module for core target screening and gene cluster analysis