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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Myricetin alleviated hydrogen peroxide-induced cellular senescence of nucleus pulposus cell through regulating SERPINE1

Fig. 1

MYR inhibited HO-induced cellular senescence. A MTT assays were used to detect the toxicity of NPCs treated with HO or MYR. *P < 0.5 VS control group. B The effect of MYR on the survival of HO-treated NPCs by MTT assay. C SA-β-Gal staining was used to detect senescence levels of NPCs treated with HO alone or co-treated with HO and MYR. D Expression levels of senescence markers (p21, p16) in NPCs treated with HO alone or co-treated with HO and MYR were detected by Western blot. E ELISA was performed to detect the expression levels of IL-6 and IL-8 in NPCs treated with HO alone or co-treated with HO and MYR. HO hydrogen peroxide, MYR Myricetin, NPCs nucleus pulposus cells

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