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Table 5 Frequencies of sensory gain and loss in CRPS based on QST

From: Pain mechanisms in complex regional pain syndrome: a systematic review and meta-analysis of quantitative sensory testing outcomes

Study

 

CDT

WDT

TSL

CPT

HPT

PPT

MPT

MPS

WUR

MDT

VDT

PHS

DMA

Maier et al. [69]

Gain

2.7%

2.5%

2.7%

30.5%

40.1%

66.3%

28.7%

46.6%

13.1%

9.5%

1.5%

9.4%

24.1%

Loss

32.5%

26.6%

26.9%

5.2%

7.7%

3.3%

10%

6.2%

2.7%

35.2%

35.4%

–

–

Gierthmühlen[15]

Gain

3.2%

2.1%

3.1%

31.7%

43.7%

66.6%

28.8%

42.8%

14.6%

11.3%

1.7%

6.4%

23.9%

Loss

29.6%

24.9%

24%

3.7%

6.4%

3.5%

8.9%

9.2%

2.3%

30.9%

32.5%

–

–

Reimer [14]

Gain

0%

0%

5.3%

36.8%

36.8%

100%

5.3%

42.1%

5.3%

5.3%

5.3%

5.3%

26.3%

Loss

31.6%

26.3%

26.3%

10.5%

5.3%

0%

5.3%

5.3%

6.7%

31.6%

42.1%

–

–

Kemler, [44]

Gain

0%

0%

–

77%

63%

85%

–

–

–

0%

–

–

–

Loss

36%

27%

–

0%

0%

0%

–

–

–

74%

–

–

–

Dietz et al. [65]

Gain

8%

6.5%

5%

50%

43%

37%

60%

44%

19%

19.5%

–

9.5%

18%

Loss

46%

42%

50%

30%

22.5%

25%

17.5%

13.5%

14.3%

64%

59.5%

–

–

Kumowski, [53]

Gain

–

–

–

17%

22%

–

33%

–

–

–

–

–

–

Loss

25%

21%

33%

–

–

–

–

–

–

–

–

–

–

  1. CRPS complex regional pain syndrome, CDT cold detection threshold, CPT cold pain threshold, DMA dynamic mechanical allodynia, HPT heat pain threshold, MDT mechanical detection threshold, MPS mechanical pain sensitivity, MPT mechanical pain threshold; PHS, paradoxical heat sensation, PPT pressure pain threshold, QST quantitative sensory testing; TSL, thermal sensory limen, VDT, vibration detection threshold; WDT, warm detection threshold; WUR, wind-up ratio