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Table 2 Comparison of the tested markers in the two groups

From: Combination of albumin-to-globulin ratio and plasma fibrinogen is a sensitive tool for preoperative screening of infected nonunion in patients undergoing reoperation after open reduction and internal fixation: a retrospective study

 

Infected group (n, 74)

Aseptic group (n, 201)

p value

WBC (109/μL)

  

0.002*

Median

6.9

6.1

 

Interquartile range

5.8–8.4

5.2–7.4

 

CRP (mg/L)

  

 < 0.001*

Median

14.1

3.6

 

Interquartile range

5.4–29.7

2.5–5.4

 

ESR (mm/h)

  

 < 0.001*

Median

17.0

9.0

 

Interquartile range

12.0–28.5

5.0–16.5

 

NLR

  

0.016*

Median

2.9

2.0

 

Interquartile range

2.0–4.1

1.6–2.5

 

MLR

  

 < 0.001*

Median

0.3

0.2

 

Interquartile range

0.2–0.4

0.2–0.3

 

PLR

  

 < 0.001*

Median

179.3

114.4

 

Interquartile range

123.0–233.4

90.3–156.7

 

PC (109/L)

  

 < 0.001*

Median

296.0

209.0

 

Interquartile range

201.3–384.3

181.0–261.5

 

Plasma D-dimer (mg/L)

  

 < 0.001*

Median

1.1

0.4

 

Interquartile range

0.5–3.1

0.2–0.8

 

Plasma fibrinogen (mg/L)

  

 < 0.001*

Median

3.8

2.7

 

Interquartile range

2.9–5.2

2.3–3.2

 

Albumin (g/L)

  

 < 0.001*

Median

38.5

41.8

 

Interquartile range

35.1–40.5

40.5 = 43.3

 

Globulin (g/L)

  

 < 0.001*

Median

32.7

26.9

 

Interquartile range

28.4–37.6

23.9–29.6

 

AGR

  

 < 0.001*

Median

1.1

1.6

 

Interquartile range

1.0–1.5

1.4–1.8

 
  1. WBC white blood cell, CRP C-reactive protein, ESR erythrocyte sedimentation rate, PC platelet count, MLR monocyte-to-lymphocyte ratio, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, AGR albumin-to-globulin ratio
  2. All p values calculated using Mann–Whitney U test
  3. *p < 0.05 indicates statistical significance